723 research outputs found

    A&T Today, Woolworth\u27s Revisited

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    A&T Today covering the reunion of the A&T Four in 1973. The cover is a picture of the original sit-in participants - Jibreel Khazan (Ezell Blair, Jr.), Franklin McCain, Joseph McNeil, and David Richmond - at the F.W. Woolworth\u27s. The table of contents includes an editor\u27s note about the reunion. The one-page article, Woolworth\u27s Revisited , discusses the details of the reunion at the F.W. Woolworth\u27s.https://digital.library.ncat.edu/atfour/1005/thumbnail.jp

    Alzheimer's disease in humans and other animals; a consequence of post-reproductive lifespan and longevity rather than ageing

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    Research in the author’s laboratories is supported by the NIHR, MRC, ARUK, Alzheimer’s Society, Wellcome Trust and the EUIntroduction Alzheimer's disease and diabetes mellitus are linked by epidemiology, genetics, and molecular pathogenesis. They may also be linked by the remarkable observation that insulin signaling sets the limits on longevity. In worms, flies, and mice, disrupting insulin signaling increases life span leading to speculation that caloric restriction might extend life span in man. It is our contention that man is already a long-lived organism, specifically with a remarkably high postfertility life span, and that it is this that results in the prevalence of Alzheimer's disease and diabetes. Methods We review evidence for this hypothesis that carries specific predictions including that other animals with exceptionally long postreproductive life span will have increased risk of both diabetes and Alzheimer's disease. Results and Conclusions We present novel evidence that Dolphin, like man, an animal with exceptional longevity, might be one of the very few natural models of Alzheimer's disease.PostprintPeer reviewe

    Disease, development, and defining indigenous identity : the emergence of machupo virus in post-revolutionary Bolivia

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    One of the four Latin American Hemorrhagic Fevers, Machupo virus, emerged in 1959 as a hemorrhagic disease in the lowlands of eastern Bolivia. The primary factor in the emergence of Machupo virus into the human population was the development of the eastern lowlands, brought about by Bolivia’s National Revolution in 1952. The Movimiento Nacionalista Revolucionario (MNR) government encouraged mass migration to eastern Bolivia in the form of resettlement programs in an attempt to stimulate the development of agriculture. By 1959 when Machupo virus first emerged, the MNR had distributed over 400,000 parcels of uncultivated land under the Agrarian Reform Act. The resultant clearing of uncultivated lands by the indigenous population was the primary factor in the emergence of Machupo virus. The United States government, in response to the burgeoning communist threat in the middle of the twentieth century, provided direction, technological assistance, and economic aid in the colonization and development of Eastern Bolivia, the region endemic to Machupo virus. Focus shifted from indigenous resettlement to immigration in order to provide a population the West perceived as capable of successful agricultural development. This shift was in response to the image of Indians provided for the West in the accounts of nineteenth-century travel writers who explored the economic advantages of the eastern lowlands. Travel writers ascribed an identity to the indigenous population resulting in a status of less than second-class citizenship in the eyes of the West, limiting them to subsistence agriculture, which contributed to the emergence of Machupo virus

    Jane Austen’s Persuasion and Wentworth’s unconscious constancy ; and, “Nay, Mama, if he is not to be animated by Cowper!”: Jane Austen, William Cowper, and Marianne Dashwood’s evocative sensibility

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    In Persuasion, Jane Austen uses Frederick Wentworth, a fundamentally unique Austen hero, to revise the eighteenth century theories of mind she has relied on in her earlier novels. Specifically, her depiction of his memory both recalls and undermines Enlightenment traditions. In her first three novels, Austen depicts memories that function along the lines of theories set forth by John Locke and Samuel Johnson. Colonel Brandon, for example, manifests Locke's theory of association in his conscious, habitual connection of Marianne with his lost love Eliza. Brandon's melancholic recollections also align with Johnson's description of afflictive, unresolvable regrets that can continually invade the mind. Moreover, manifold Austen characters rely on Johnson's formulation of memory's primarily moral use; at pivotal moments in their development, characters as disparate as Marianne and Darcy look back on their past actions to assess their behavior, discover their shortcomings, and derive the impetus to change. Though Austen continues to employ these models in her depiction of Wentworth, she also subjects them to significant revisions that resemble depictions of memory by contemporary Romantic writers. Wentworth, locked in contradiction, attempts to expel painful regrets of Anne with a Johnsonian reliance on logic and industriousness. In the process, however, he continually reassesses Anne's past significance to him, violating the eighteenth-century conviction of memory's static fixity and invoking William Wordsworth's depictions of memories that can change and grow beyond their original contexts. Similarly, he engages in Johnson's process of reviewing and learning from his past behavior, only to evince a serious misremembering in the midst of his moral reform. This depiction of memory evokes Byron's work in the Turkish Tales, and it is characteristic of the novel, manifested in Mrs. Musgrove's unexpected surge of grief for her dead son, in Anne's "retentive feelings" for Wentworth, and in Wentworth's breakdown on the Cobb. Austen continues to rely on eighteenth-century models, but she revises them in ways that recall Romantic writers like Wordsworth and Byron. In Wentworth's character and in Persuasion as a whole, Austen engages in a unique experiment that utilizes and even amalgamates the divergent traditions. ...AND... Jane Austen's particular enjoyment of the poetry of William Cowper, though often treated as a critical commonplace, is rarely taken into account in discussions of her work. However, Austen's references to the poet in her novels suggest that Cowper, whether read aloud by Edward Ferrars or quoted from memory by Fanny Price, remained a serious influence, both in theme and in craft. In Sense and Sensibility in particular, Austen places Cowper at the crux of Marianne's cultivated sensibility and her relation to the outside world. Though Marianne's reliance on literary convention in her enacted sensibility is often treated by critics as proof of her affectation and of the ultimate inadequacy of her worldview, a closer look at Austen's evocations of Cowper's poetry in Marianne's habits and attitudes shows a more complex picture. While Marianne's habits and passions evoke a variety of literary precedents, an examination of the character's connections to Cowper offers a unique perspective on her connection to rural nature and on her responses to suffering. Austen's character "reads" and enacts Cowper's ideas not merely to form fallacious conclusions and indulge in deleterious habits, but also to enrich and expand her inner life. Ultimately, Austen uses Cowper's fond and nuanced description of a rural, domestic life in communion with nature to give Marianne the resources to handle dislocation and suffering, and she evokes his model of irreparably isolating pain in Marianne's breakdown, depicting her sensibility as a complex and ambiguous trait that can turn in upon itself to isolate her from others, can effect a larger protest against her disenfranchisement, and can ultimately give her the tools to heal

    Hell, maybe it's you, Adam: the mimetics of troubled identifications in Paradise Lost

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    Adam, as does every male character in this text, is only listening to himself speak, not Eve. Indeed, Eve is merely a projection of Adam – a mirror, as it were, of his own thoughts and fears. Milton has placed many of these miscommunication mirrors throughout the text, and the celestial light of misunderstanding bounces continually in all directions. It is my contention that there is a trinity of triangles occurring in each instance of verbal exchange in Paradise Lost – a series of prisms of mirrors. Each instance of triangular mirroring is one of three types. There is, firstly, a recurrent mirroring that happens at the directly conversational level, involving three gendered subject positions: a masculine self, a feminized other, and God’s textual law. We’ll call this tripartite template the rhetorical mirroring. The images repeat, as this creates mirroring that occurs at another level, for the three characters who each play the same role in the tripartite scenario: God, Satan, and Adam. These three males each occupy the masculine position of the template, and share specific commonalities in their dispositions toward their respective others, as if they are all mirror images of one another. This we will call masculine mirroring. The third level of mirroring occurs existentially during the act of reading -- by setting up for the reader an identification with Adam, Milton therefore turns a mirror on the reader, and offers a text that works as a cipher. These three planes, the rhetorical mirror, the masculine mirror, and the narrative mirror, further make up a metatextual triangular prism. In a prismatic reading of the text, we can see how we project our own images and phantoms, but hopefully we’ll also see how the true colors of that mysterious light that is our own is reflected back to us, revealing our own constituent hues

    Painting and collage : search, surface, and surprise

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    Search from a painter's point of view is a pre-condition of personal creativity. If I knew all the ways of searching, I would be more than one person and that, of course, is impossible. The painter is ONE, one who moves in the direction of his choice. Search is technical. Search is spiritual. Search is fundamental. Search is inevitable in the life of a painter. Often when a form is determined and a color harmony is established, in the revelation of a painting, there is a month of July celebration in the painter's heart. In my life this celebration may last ten minutes. The statement which the painting is making is a success. I see the painting. The painting sees me

    When is the appropriate time to pursue nurse practitioner practice legislation? : a case study

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    In the United States, many states have revised their nurse practice acts to include provisions that promote full practice authority for nurse practitioners. Such revisions reflect the expanded qualifications and abilities of nurse practitioners and provide a mechanism by which to better utilize the full scope of nurse practitioner services that are available to address growing demands for access to health care. Although the research literature is beginning to describe strategies that states have used to successfully achieve regulatory changes to full practice authority for nurse practitioners, no published study identified in the literature has explored how stakeholders within a state decide on the appropriate time to pursue such legislation. This is the first known study to use an embedded single case study design, guided by the Kingdon (2011) policy stream model, to provide a detailed account of how stakeholders for nurse practitioner full practice authority in one stated determined the appropriate time to pursue legislative changes to nurse practitioner scope of practice regulations. Qualitative data analysis was guided by Yin (2014), and used theoretical propositions, the development of a case description, pattern matching, and explanation building. Findings from the study addressed the research question by revealing four themes which included the components considered by the study state’s stakeholders as they determined the appropriate time to pursue legislation to change nurse practitioner scope of practice regulations. Study findings can be used as a reference to increase the competency with which the nursing profession pursues the policy process for full practice authority legislation, and can be used by stakeholders in other states as a guide for the assessment components to consider when making decisions to pursue related legislation

    Discovering through the act of making

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    My drawing subject is the human form. I focus on my own body in my large scale, and text-related pieces. I also work from direct observation and invention. I am actively searching for ways to express my gender identity and sexuality. With the drawing, collage and free writing, I broaden my notions of what it means to reconstruct while I simultaneously deconstructing the human form. Creating the form in public reveals how it's created. The materials and public performance further aid me in my quest to establish and maintain my identity(s) as a gay black male. I am attempting to dissect and explore each facet of what it means to be a gay person and a person of color in the 21st century
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