Stepwise assembly of heterometallic, heteroleptic "triblock Janus-type" metal-organic polyhedra

Increasing the chemical complexity of metal-organic cages (MOCs) or polyhedra (MOPs) demands control over the simultaneous organization of diverse organic linkers and metal ions into discrete caged structures. Herein, we show that a pre-assembled complex of the archetypical cuboctahedral MOP can be used as a template to replicate such caged structure, one having a "triblock Janus-type" configuration that is both heterometallic and heteroleptic. We present a novel strategy to assemble diverse metal ions and organic linkers into metal-organic polyhedra (MOPs). It involves use of a pre-assembled complex of a parent MOP to replicate this cage with a multicomponent character

Stepwise assembly of heterometallic, heteroleptic "triblock Janus-type" metal-organic polyhedra

Increasing the chemical complexity of metal-organic cages (MOCs) or polyhedra (MOPs) demands control over the simultaneous organization of diverse organic linkers and metal ions into discrete caged structures. Herein, we show that a pre-assembled complex of the archetypical cuboctahedral MOP can be used as a template to replicate such caged structure, one having a "triblock Janus-type" configuration that is both heterometallic and heteroleptic.This work was supported by the Spanish MINECO (project RTI2018-095622-B-I00), the Catalan AGAUR (project 2021 SGR 00458), the CERCA Program/Generalitat de Catalunya, and the MCIN/AEI/10.13039/501100011033. ICN2 is supported by the Severo Ochoa program from the Spanish MINECO (grant SEV-2017-0706). The project that gave rise to these results received the support of a fellowship (LCF/BQ/PR20/11770011) from “la Caixa” Foundation (ID 100010434). C.v.B. thanks the Austrian Science Fund (FWF), Erwin Schrödinger fellowship for supporting the project J 4637.Peer reviewe