Preferences for potential innovations in non-invasive colorectal cancer screening: A labeled discrete choice experiment for a Dutch screening campaign

<div><p></p><p><b>Background.</b> The introduction of innovative non-invasive screening tests (e.g. tests based on stool and blood samples or both) may be a solution to increase colorectal cancer (CRC) screening uptake. However, preferences for these non-invasive screening tests have not been investigated in great detail yet. The purpose of this article therefore is to elicit individuals’ preferences for different non-invasive screening tests in a Dutch screening campaign context.</p><p><b>Material and methods</b>. We investigate preferences by means of a labeled discrete choice experiment. Data of 815 individuals, aged 55–75 years, are used in the analysis.</p><p><b>Results</b>. Multinomial logit model analysis showed that the combi-test is generally preferred over the blood-test and the (currently available) stool-test. Furthermore, besides the large effect of screening test type, there are significant differences in preference depending on participants’ socio-demographic background. Finally, the analysis showed a significant positive effect on screening test choice for the attributes sensitivity, risk reduction, and level of evidence and a non-significant effect for the attribute unnecessary follow-up test.</p><p><b>Conclusion</b>. Introducing new non-invasive screening tests that are based on a combination of stool and blood samples (or blood sample only) has the potential to increase CRC screening participation compared to the current standard stool-based test.</p></div

Results Systematic review sustainability

For this review, 4219 items were retrieved and screened based on title and abstract, 185 studies were assessed based on full text reading and 14 studies were selected for analyses. This data file contains the endnote file with all items and the classification

Stepwise procedure of CS quality indicator development.

<p>Stepwise procedure of CS quality indicator development.</p