600 research outputs found

    Apocalypse in a Minor Key

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    Study of Supportive Housing in Illinois: First Interim Report

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    In particular, the study focuses on the change in service use and the cost of services used by Illinois supportive housing residents 2 years before entering supportive housing and 2 years after. This study will inform policymakers, funders, and others about the importance and cost effectiveness of supportive housing in Illinois

    Sparrowhawk movement, calling, and presence of dead conspecifics differentially impact blue tit (Cyanistes caeruleus) vocal and behavioral mobbing responses

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    Funding: UK NERC (NE/J018694/1), Royal Society (RG2012R2), M.J. Murdock Charitable Trust (2014199), University of St Andrews 600th Year Scholarship, University of St Andrews St Leonard's Fee Scholarship.Many animals alter their anti-predator behavior in accordance to the threat level of a predator. While much research has examined variation in mobbing responses to different predators, few studies have investigated how anti-predator behavior is affected by changes in a predator’s own state or behavior. We examined the effect of sparrowhawk (Accipiter nisus) behavior on the mobbing response of wild blue tits (Cyanistes caeruleus) using robotic taxidermy sparrowhawks. We manipulated whether the simulated predator moved its head, produced vocalizations, or held a taxidermy blue tit in its talons. When any sparrowhawk model was present, blue tits decreased foraging and increased anti-predator behavior and vocalizations. Additionally, each manipulation of the model predator’s state (moving, vocalizing, or the presence of a dead conspecific) impacted different types of blue tit anti-predator behavior and vocalizations. These results indicate that different components of mobbing vary according to the specific state of a given predator—beyond its presence or absence—and suggest that each might play a different role in the overall mobbing response. Last, our results indicate that using more life-like predator stimuli—those featuring simple head movements and audio playback of vocalizations—changes how prey respond to the predator; these ‘robo-raptor’ models provide a powerful tool to provide increased realism in simulated predator encounters without sacrificing experimental control.Publisher PDFPeer reviewe

    Bridging the Gap from New Graduate to Practicing Occupational Therapist: An Educational Resource in Orthopedics

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    OT is pivotal in the rehabilitation and recovery of individuals with orthopedic conditions (Nelson, 2010). However, as a new graduate occupational therapist, there is limited support as they make the transition to clinical practice (Turpin et al., 2021). New graduates receive support through professional mentorship and peer support but are often focused on the safe practice of basic skills rather than on best practices (Opoku et al., 2021). New graduates would feel more confident in clinical judgment and decision-making with additional support from mentors and accessible up-to-date resources (Adam et al., 2013). Purpose: Develop an accessible resource for new occupational therapists entering the orthopedic setting.https://soar.usa.edu/otdcapstonesfall2023/1009/thumbnail.jp

    The Iowa Homemaker vol.11, no.1

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    On a Milan Church Wall By Edna Rhoades A. A. Dame Fashion to the Front By Helen Penrose Please Ma – Lemme Have a Dog By Prudence Tomlinson If Today is Wash Day By Thelma Carlso

    Phospholipase D promotes Arcanobacterium haemolyticum adhesion via lipid raft remodeling and host cell death following bacterial invasion

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    <p>Abstract</p> <p>Background</p> <p><it>Arcanobacterium haemolyticum </it>is an emerging bacterial pathogen, causing pharyngitis and more invasive infections. This organism expresses an unusual phospholipase D (PLD), which we propose promotes bacterial pathogenesis through its action on host cell membranes. The <it>pld </it>gene is found on a genomic region of reduced %G + C, suggesting recent horizontal acquisition.</p> <p>Results</p> <p>Recombinant PLD rearranged HeLa cell lipid rafts in a dose-dependent manner and this was inhibited by cholesterol sequestration. PLD also promoted host cell adhesion, as a <it>pld </it>mutant had a 60.3% reduction in its ability to adhere to HeLa cells as compared to the wild type. Conversely, the <it>pld </it>mutant appeared to invade HeLa cells approximately two-fold more efficiently as the wild type. This finding was attributable to a significant loss of host cell viability following secretion of PLD from intracellular bacteria. As determined by viability assay, only 15.6% and 82.3% of HeLa cells remained viable following invasion by the wild type or <it>pld </it>mutant, respectively, as compared to untreated HeLa cells. Transmission electron microscopy of HeLa cells inoculated with <it>A. haemolyticum </it>strains revealed that the <it>pld </it>mutant was contained within intracellular vacuoles, as compared to the wild type, which escaped the vacuole. Wild type-infected HeLa cells also displayed the hallmarks of necrosis. Similarly inoculated HeLa cells displayed no signs of apoptosis, as measured by induction of caspase 3/7, 8 or 9 activities.</p> <p>Conclusions</p> <p>These data indicate that PLD enhances bacterial adhesion and promotes host cell necrosis following invasion, and therefore, may be important in the disease pathogenesis of <it>A. haemolyticum </it>infections.</p

    Docosahexaenoic acid (DHA) and arachidonic acid (ARA) balance in developmental outcomes

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    The DHA Intake and Measurement of Neural Development (DIAMOND) trial represents one of only a few studies of the long-term dose-response effects of LCPUFA-supplemented formula feeding during infancy. The trial contrasted the effects of four formulations: 0.00% docosahexaenoic acid (DHA)/0.00% arachidonic acid (ARA), 0.32% DHA/0.64% ARA, 0.64% DHA/0.64% ARA, and 0.96% DHA/0.64% ARA against a control condition (0.00% DHA/0.00% ARA). The results of this trial have been published elsewhere, and show improved cognitive outcomes for infants fed supplemented formulas, but a common finding among many of the outcomes show a reduction of benefit for the highest DHA dose (i.e., 0.96% DHA/0.64% ARA, that is, a DHA: ARA ratio 1.5:1.0). The current paper gathers and summarizes the evidence for the reduction of benefit at this dose, and in an attempt to account for this reduced benefit, presents for the first time data from infants' red blood cell (RBC) assays taken at 4 and 12 months of age. Those assays indicate that blood DHA levels generally rose with increased DHA supplementation, although those levels tended to plateau as the DHA-supplemented level exceeded 0.64%. Perhaps more importantly, ARA levels showed a strong inverted-U function in response to increased DHA supplementation; indeed, infants assigned to the formula with the highest dose of DHA (and highest DHA/ARA ratio) showed a reduction in blood ARA relative to more intermediate DHA doses. This finding raises the possibility that reduced ARA may be responsible for the reduction in benefit on cognitive outcomes seen at this dose. The findings implicate the DHA/ARA balance as an important variable in the contribution of LCPUFAs to cognitive and behavioral development in infancy

    The Iowa Homemaker vol.4, no.7

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    Table of Contents Accomplish Your Work by Scheduling Your Time by Gertrude Lynn, page 3 A Vision Come True by Eveleth Pederson, page 4 Norwegian Cookery by Ethel Rayness, page 4 Flowers as Decoration by Sarah Palon, page 5 Glimpses Into Child Problems by Helen Herr, page 6 “That School Girl Complexion” by Mrs. Linda S. Brown, page 7 Attractive, Tho Inexpensive Hangings by Grace Heidbreder, page 7 “Women’s Place In The Home?” by Eleanor Murray, page 8 Silverware by Edna Carlson, page 9 Successful Cake Baking by Pauline Peacock, page 10 Who’s There and Where by Helen Putnam, page 11 Editorial Page, page 12 Eternal Question, page 13 Homemaker as Citizen, page 1
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