Software for the analysis of mutations at the human hprt gene

A computerized database containing DNA sequence information regarding human HPRT mutants has been created. The database itself is in the dBASE format and contains information on about 1500 mutants. In addition, an IBM PC compatible software package to analyze the information in the database has been developed. Both the database and software are freely available via the Internet

Fidelity of Thermococcus litoralis DNA polymerase (Vent TM ) in PCR determined by denaturing gradient gel electrophoresis

DNA synthesis fidelities of two thermostable DNA polymerases, Thermus aquaticus (Taq) and Thermococcus litoralis (Tli, also known as Ven

Volatile compared with total intravenous anaesthesia in patients undergoing high-risk cardiac surgery: a randomized multicentre study

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Phomopsis bougainvilleicola prepatellar bursitis in a renal transplant recipient

Prepatellar bursitis is typically a monomicrobial bacterial infection. A fungal cause is rarely identified. We describe a 61-year-old man who had received a renal transplant 21 months prior to presentation whose synovial fluid and surgical specimens grew Phomopsis bougainvilleicola, a pycnidial coelomycete

Meromorphic traveling wave solutions of the complex cubic-quintic Ginzburg-Landau equation

We look for singlevalued solutions of the squared modulus M of the traveling wave reduction of the complex cubic-quintic Ginzburg-Landau equation. Using Clunie's lemma, we first prove that any meromorphic solution M is necessarily elliptic or degenerate elliptic. We then give the two canonical decompositions of the new elliptic solution recently obtained by the subequation method.Comment: 14 pages, no figure, to appear, Acta Applicandae Mathematica

Overcoming the mobility penalty introduced by dipole disorder in small-molecule HTM films

The importance of the hole-transport material (HTM) in perovskite solar cells (PSCs) is now very well-established, with state-of-the-art materials such as Spiro-OMeTAD attracting significant attention in the last decade. The high cost of such materials still limits the commercialisation of these HTMs. To tackle this, the amide linker has recently been introduced into HTM systems via EDOT-Amide-TPA, utilising condensation chemistry as a cheap and effective route to HTMs. EDOT-Amide-TPA is capable of a variety of intermolecular interactions such as dipole-dipole interactions and hydrogen bonding, both of which are beneficial for enhancing the film morphology and improving charge transport. However, the interplay between these different interactions is not trivial, and understanding how they affect each other is paramount to inform new HTM designs whilst minimising material waste. To date, studies investigating the combined effects of different intermolecular interactions within the HTL on the charge transport properties of these materials are lacking. Furthermore, dipole disorder within the film introduces a mobility ‘penalty’: mobility decreases with stronger overall dipole due to energetic disorder within the film, which hinders charge hopping. In this work, we investigate three amide-based HTM analogs with differing intermolecular interaction capabilities, and show that this penalty can be compensated by a preferentially increased dipole ordering, likely achieved through intermolecular hydrogen bonding. This effectively cancels out the dipole disorder while retaining the beneficial effects on the molecular packing. Our aim is that this work provides a good foundation for navigating the complex interplay between hydrogen bonding, dipole moments, conductivity, and film formation in small-molecule HTM

On elliptic solutions of the cubic complex one-dimensional Ginzburg-Landau equation

The cubic complex one-dimensional Ginzburg-Landau equation is considered. Using the Hone's method, based on the use of the Laurent-series solutions and the residue theorem, we have proved that this equation has neither elliptic standing wave nor elliptic travelling wave solutions. This result amplifies the Hone's result, that this equation has no elliptic travelling wave solutions.Comment: LaTeX, 12 page