ДОКАЗИ ТОЧНИХ НАУК ЩОДО ІСНУВАННЯ РОЗУМНОГО ЗАДУМУ. (EVIDENCE FROM THE EXACT SCIENCES FOR INTELLIGENT DESIGN.)

Визначається та обговорюється парадигма Розумного Задуму. Наводяться докази точного доопрацювання фундаментальних постійних величин та передумов стандартної моделі Великого Вибуху, яка підтримувала ідею виникнення планети, що створює умови для життя людини. Розумний Задум як вищу наукову парадигму, як обговорюється у цій статті, можливо найбільш вичерпно показати на прикладі молекулярної біології. (The intelligent design (ID) paradigm is defined and discussed. Representative evidence of precise fine tuning in fundamental constants and initial conditions for the standard model of the Big Bang, to produce a planet which can support human life is presented. ID as a superior scientific paradigm will probably be fully shown in molecular biology we argue.

The Absorption of Sound in Suspensions and Emulsions. I. Water Fog in Air

The suspended particles are approximated by spheres and the diffraction problem for a fluid sphere in a fluid medium is solved taking into consideration viscosity and thermal conduction. The results are discussed numerically for water droplets in air and a satisfactory agreement with Knudsen's attenuation measurements in water fog is found

Does psychedelic therapy have a transdiagnostic action and prophylactic potential?

Addressing global mental health is a major twenty-first century challenge. Current treatments have recognised limitations; in this context, new ones that are prophylactic and effective across diagnostic boundaries would represent a major advance. The view that there exists a core of transdiagnostic overlap between psychiatric disorders has re-emerged in recent years, and evidence that psychedelic therapy holds promise for a range of psychiatric disorders supports the position that it may be trans diagnostically effective. Here we propose that psychedelic therapy's core, trans diagnostically relevant action, lies in its ability to increase neuronal and mental plasticity, thus enhancing the potential for change, which we consider to be a key to its therapeutic benefits. Moreover, we suggest that enhanced plasticity via psychedelics, combined with a psychotherapeutic approach, can aid healthy adaptability and resilience, protective factors for long-term well-being. We present candidate neurological , and psychological markers of this plasticity and link them with a predictive processing model of the action of psychedelics. We propose that a model of psychedelic induced plasticity combined with an adequate therapeutic context has prophylactic and transdiagnostic potential, implying that it could have abroad, positive impact on public health

Understanding the Relationship Between Resources in Institutional Characteristics and Student Mobilization in Higher Education Institutions

In 2015, a national student organization called the Black Liberation Collective, composed of local student organizations at multiple institutions, initiated, led protests, and issued demands to institutions across the United States. The student organizations that mobilized occurred at institutions with more resources including higher endowments, tuition, and faculty wages. This study used cross-sectional data on 4-year public and private not-for-profit institutions from the Integrated Postsecondary Education Data System to investigate the institutional characteristics that predict student organizations that protested. Evidence indicates that institutions that are more selective and have larger enrollment sizes with higher percentages of undergraduate Black students and lower percentages of Pell Grant recipients have a greater likelihood of student organizations mobilizing on their campuses

Correction to: The hidden therapist: evidence for a central role of music in psychedelic therapy.

The article The hidden therapist: evidence for a central role of music in psychedelic therapy, written by Mendel Kaelen, Bruna Giribaldi, Jordan Raine, Lisa Evans, Christopher Timmerman, Natalie Rodriguez, Leor Roseman, Amanda Feilding, David Nutt, Robin Carhart-Harris, was originally published electronically on the publisher's internet portal

Sustained, multifaceted improvements in mental well-being following psychedelic experiences in a prospective opportunity sample

In the last 15 years, psychedelic substances, such as LSD and psilocybin, have regained legitimacy in clinical research. In the general population as well as across various psychiatric populations, mental well-being has been found to significantly improve after a psychedelic experience. Mental well-being has large socioeconomic relevance, but it is a complex, multifaceted construct. In this naturalistic observational study, a comprehensive approach was taken to assessing well-being before and after a taking a psychedelic compound to induce a “psychedelic experience.” Fourteen measures of well-being related constructs were included in order to examine the breadth and specificity of change in well-being. This change was then analysed to examine clusters of measures changing together. Survey data was collected from volunteers that intended to take a psychedelic. Four key time points were analysed: 1 week before and 2 weeks, 4 weeks, and 2 years after the experience (N = 654, N = 315, N = 212, and N = 64, respectively). Change on the included measures was found to cluster into three factors which we labelled: 1) “Being well”, 2) “Staying well,” and 3) “Spirituality.” Repeated Measures Multivariate Analysis of Variance revealed all but the spirituality factor to be improved in the weeks following the psychedelic experience. Additional Mixed model analyses revealed selective increases in Being Well and Staying Well (but not Spirituality) that remained statistically significant up to 2 years post-experience, albeit with high attrition rates. Post-hoc examination suggested that attrition was not due to differential acute experiences or mental-health changes in those who dropped out vs. those who did not. These findings suggest that psychedelics can have a broad, robust and sustained positive impact on mental well-being in those that have a prior intention to use a psychedelic compound. Public policy implications are discussed

Psilocybin with psychological support improves emotional face recognition in treatment-resistant depression

RATIONALE: Depressed patients robustly exhibit affective biases in emotional processing which are altered by SSRIs and predict clinical outcome. OBJECTIVES: The objective of this study is to investigate whether psilocybin, recently shown to rapidly improve mood in treatment-resistant depression (TRD), alters patients' emotional processing biases. METHODS: Seventeen patients with treatment-resistant depression completed a dynamic emotional face recognition task at baseline and 1 month later after two doses of psilocybin with psychological support. Sixteen controls completed the emotional recognition task over the same time frame but did not receive psilocybin. RESULTS: We found evidence for a group × time interaction on speed of emotion recognition (p = .035). At baseline, patients were slower at recognising facial emotions compared with controls (p < .001). After psilocybin, this difference was remediated (p = .208). Emotion recognition was faster at follow-up compared with baseline in patients (p = .004, d = .876) but not controls (p = .263, d = .302). In patients, this change was significantly correlated with a reduction in anhedonia over the same time period (r = .640, p = .010). CONCLUSIONS: Psilocybin with psychological support appears to improve processing of emotional faces in treatment-resistant depression, and this correlates with reduced anhedonia. Placebo-controlled studies are warranted to follow up these preliminary findings

Readiness for Reform in Middle Schools Adopting PowerTeaching for Mathematics Instruction

Federal policy makers and school leaders increasingly recognize middle school math as a turning point in students’ academic success, especially in predicting high school graduation rates. New i3 scale-up grants allow large-scale implementation of proven reforms that increase student achievement. PowerTeaching (PT) is one such reform that centers on cooperative learning. A five year technologically-facilitated scale-up of PowerTeaching will bring the reform to 185 high-needs middle schools nationwide. In this pilot phase of the project, we will examine eight schools’ readiness for reform. Teacher questionnaires, interviews with school leaders, PT coaches and teachers, coaching feedback, and walk-through observation data will be used to determine school characteristics that impacted the initial implementation of the PT model and promote formative evaluation efforts

DMT alters cortical travelling waves

Psychedelic drugs are potent modulators of conscious states and therefore powerful tools for investigating their neurobiology. N,N, Dimethyltryptamine (DMT) can rapidly induce an extremely immersive state of consciousness characterized by vivid and elaborate visual imagery. Here, we investigated the electrophysiological correlates of the DMT-induced altered state from a pool of participants receiving DMT and (separately) placebo (saline) while instructed to keep their eyes closed. Consistent with our hypotheses, results revealed a spatio-temporal pattern of cortical activation (i.e. travelling waves) similar to that elicited by visual stimulation. Moreover, the typical top-down alpha-band rhythms of closed-eyes rest were significantly decreased, while the bottom-up forward wave was significantly increased. These results support a recent model proposing that psychedelics reduce the ‘precision-weighting of priors’, thus altering the balance of top-down versus bottom-up information passing. The robust hypothesis-confirming nature of these findings imply the discovery of an important mechanistic principle underpinning psychedelic-induced altered states