Local null controllability of the N-dimensional Navier-Stokes system with N-1 scalar controls in an arbitrary control domain

In this paper we deal with the local null controllability of the N-dimensional Navier-Stokes system with internal controls having one vanishing component. The novelty of this work is that no condition is imposed on the control domain

MOJAVE: Monitoring of Jets in AGN with VLBA Experiments. IV. The Parent Luminosity Function of Radio-Loud Blazars

(Abridged) We use a complete sample of active galactic nuclei (AGN) selected on the basis of relativistically beamed 15 GHz radio flux density to derive the parent radio luminosity function (RLF) of bright radio-selected blazar cores. We use a maximum likelihood method to fit a beamed RLF to the observed data and thereby recover the parameters of the intrinsic (unbeamed) RLF. We analyze two subsamples of the MOJAVE sample: the first contains only objects of known FR II class, with a total of 103 sources, and the second subsample adds 24 objects of uncertain FR class for a total of 127 sources. Both subsamples exclude four known FR I radio galaxies and two gigahertz-peaked spectrum sources. We obtain good fits to both subsamples using a single power law intrinsic RLF with pure density evolution function. We find that a previously reported break in the observed MOJAVE RLF actually arises from using incomplete bins (because of the luminosity cutoff) across a steep and strongly evolving RLF, and does not reflect a break in the intrinsic RLF. The derived space density of the parent population of the FR II sources from the MOJAVE sample (with L>1.3e25 W/Hz) is approximately 1600/Gpc^3.Comment: 31 pages, 7 figures and 2 tables. Accepted for publication in ApJ. Changes: classification of sources based on radio morphology instead of optical classes; added the parameters of the RLF of the FR II sources; added more explanations; added a table listing the sample sources; added 2 extra figures related to the observed break in the RLF; updated reference

Competition, efficiency and collective behavior in the "El Farol" bar model

The El Farol bar model, proposed to study the dynamics of competition of agents in a variety of contexts (W. B. Arthur, Amer. Econ. Assoc. Pap. and Proc. 84, 406 (1994)) is studied. We characterize in detail the three regions of the phase diagram (efficient, inefficient and better than random) of the simplest version of the model (D. Challet and Y.-C. Zhang, Physica A, 246, 407 (1997)). The efficient region is shown to have a rich structure, which is investigated in some detail. Changes in the payoff function enhance further the tendency of the model towards a wasteful distribution of resources.Comment: 7 pages Latex, 7 Postscript figures; changed reference, acknowledgments included. Accepted for publication in Europen Physics Journal

ACM/IEEE-CS information technology curriculum 2017: A status update

The IT2008 Curriculum Guidelines for Undergraduate Degree Programs in Information Technology has been showing its age, and in 2014, the ACM Education Board agreed to oversee the creation of a revision, now being referred to as IT2017. Much progress has been made, and a version 0.6 will be ready by Oct 2016. All proposed panel members are members of the IT2017 Task Group

Improving Dental Care to the Elderly in a Nursing Home

The project is about the collaboration between Peninsula Health Care District (PHCD) and Apple Tree Dental (ATD) in a team approach to address the current issues of improving dental care of frail and elderly patients in nursing home facilities. The specific aim is to improve dental care of clients at the San Mateo County nursing home facility by 100% by May, 2015. The methods use in this project was the adaptation and implementation of existing dental/oral health assessment tools, that is nurse driven for patient assessment upon admission to the nursing facility. The process includes staff education regarding the adapted assessment tool and the identification of champions to provide for residents self-care deficits. The activities completed, were several meetings were held by the CNL student, ATD director and Registered Dental Hygienist (RDH) and the preceptor. The assessment tool was approved by PHCD and ATD. It was evaluated by 2 nurse champions and modifications were made. The implementation of the tool has not been initiated in the nursing home due to the fact that the nursing facility has not signed the contract with ATD. ATD opened their center and there were 8 staff members attended the short educational session about improving dental care for the elderly in nursing home facilities. The activities not completed were, the assessment tool was not for dental care assessment for the elderly in the nursing home facilities. If it was used as planned, the improvement of dental care in the nursing home would increase at least 75% with compliancy of the patient and staff members. It would have been an effective assessment tool in the emergency room, the ICU or the medical surgical floors. The nurses will fill out the assessment and make the recommendations of referring the elderly patients to ATD upon discharge. Continued education, feedback and continued gathering of data would be necessary to determine the effectiveness of the tool

Geomicrobiology of the ocean crust : the phylogenetic diversity, abundance, and distribution of microbial communities inhabiting basalt and implications for rock alteration processes

Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution June 2007Basaltic ocean crust has the potential to host one of the largest endolithic communities on Earth. This portion of the biosphere, however, remains largely unexplored. In this study, we utilize molecular biological, microscopic, and geochemical tools to gain a better understanding of the geomicrobiology of the ocean crust. Specifically, we examine the phylogenetic diversity of microorganisms inhabiting basaltic lavas, the activities and abundances of these microorganisms, the spatial extent of the biosphere, and the potential effect that microbial activity has on the geochemistry of the ocean crust and overlying water column. Our study demonstrates that young, fresh volcanic lavas near mid-ocean ridges host an incredibly diverse and dense population of microorganisms dominated by Bacteria, quite distinct from the microbial communities found in surrounding deep seawater and hydrothermal vents. Furthermore, these communities may contribute to the elemental cycling of Fe, S, Mn, N, and C in this environment. The inability to definitively identify microorganisms in drill-cores of old (> 15 Ma) ocean crust, however, implies that these once prolific communities may become scarce as the crust ages and moves further away from the ridge axis. Finally, we provide evidence suggesting that these communities are fueled by oxidative alteration reactions occurring in the basaltic crust.Funding for this project came from: RIDGE 2000 Grant #OCE-0241791 awarded to Katrina J. Edwards and Wolfgang Bach, the NASA Astrobiology Institute - Cycle 3 CAN-02-OSS-02 awarded to Katrina J. Edwards, USSSP ODP Post-cruise funding Grant #TX A&M F001724 awarded to Cara M. Santelli and Katrina J. Edwards, and a Schlanger Ocean Drilling Fellowship awarded to Cara M. Santelli

Table of Contents & Masthead

Journal of the National Association of Administrative Law Judiciary, NAALJ, Contents, editorial board, Pepperdine University, Caruso School of La

Approaches and Considerations Towards a Safe and Effective Adeno-Associated Virus Mediated Therapeutic Intervention for GM1-Gangliosidosis: A Dissertation

GM1 gangliosidosis is a lysosomal storage disorder caused by a deficiency in the catabolizing enzyme β-galactosidase (βgal). This leads to accumulation of GM1-ganglioside (GM1) in the lysosome inducing ER stress and cell death. GM1 gangliosidosis is primarily a disorder of the central nervous system (CNS) with peripheral organ involvement. In this work we report two major findings, 1) systemic treatment of GM1 gangliosidosis with an adenoassociated virus (AAV9) encoding mouse-βgal (mβgal) in a GM1 gangliosidosis mouse model (βGal-/-), and 2) an investigation into an intracranial injection of a therapeutic AAVrh8 encoding mβgal. Systemic treatment of GM1 gangliosidosis with AAV9 resulted in a moderate expression of enzyme in the CNS, reduction of GM1 storage, significant retention of motor function and a significant increase in lifespan. Interestingly, the therapeutic effect was more robust in females. Intracranial injections of AAVrh8 vector expressing high levels of βgal resulted in enzyme spread throughout the brain, significant retention of motor function and a significant increase in lifespan. Histological alterations were also found at the injection site in both βGal-/- and normal animals. We constructed a series of vectors with a range of decreasing enzyme expression levels to investigate the cause for the unanticipated result. Microarrays were performed on the injection site and we showed that a lower expressing AAVrh8-mβgal vector mitigated the negative response. Intracranial injection of this newly developed vector was shown to clear lysosomal storage throughout the CNS of βGal-/- mice. Taken together, these studies indicate that a combined systemic and fine-tuned intracranial approach may be the most effective in clearing lysosomal storage completely in the CNS while providing therapeutic benefit to the periphery

Prognostic Indicators of Cardiovascular Risk in Renal Disease

Although the annual mortality rate for end-stage renal disease (ESRD) is decreasing, likely due to an increase in kidney transplantation rate, the survival probability for ESRD patients from day one of dialysis has not changed, and is still poor with a 5-year survival rate of approximately 34%. This is contributed to by a high prevalence of cardiovascular disease, which is the leading cause of death in ESRD patients. In order to improve survival outcomes, patients at high risk of cardiovascular related mortality need to be identified. Heart rate variability (HRV), baroreceptor sensitivity, and baroreceptor reflex effectiveness index can be used to assess heart rate control and may predict cardiovascular mortality. This paper will discuss how HRV, baroreceptor sensitivity, and baroreceptor reflex effectiveness index are altered in renal disease and the utility of these indices as markers of cardiac risk in this patient population