126 research outputs found
On the spectral problem of N=4 SYM with orthogonal or symplectic gauge group
We study the spectral problem of N=4 SYM with gauge group SO(N) and Sp(N). At
the planar level, the difference to the case of gauge group SU(N) is only due
to certain states being projected out, however at the non-planar level novel
effects appear: While 1/N-corrections in the SU(N) case are always associated
with splitting and joining of spin chains, this is not so for SO(N) and Sp(N).
Here the leading 1/N-corrections, which are due to non-orientable Feynman
diagrams in the field theory, originate from a term in the dilatation operator
which acts inside a single spin chain. This makes it possible to test for
integrability of the leading 1/N-corrections by standard (Bethe ansatz) means
and we carry out various such tests. For orthogonal and symplectic gauge group
the dual string theory lives on the orientifold AdS5xRP5. We discuss various
issues related to semi-classical strings on this background.Comment: 25 pages, 3 figures. v2: Minor clarifications, section 5 expande
Form factors of chiral primary operators at two loops in ABJ(M)
archiveprefix: arXiv primaryclass: hep-th reportnumber: NORDITA-2013-34 slaccitation: %%CITATION = ARXIV:1305.2422;%%archiveprefix: arXiv primaryclass: hep-th reportnumber: NORDITA-2013-34 slaccitation: %%CITATION = ARXIV:1305.2422;%%archiveprefix: arXiv primaryclass: hep-th reportnumber: NORDITA-2013-34 slaccitation: %%CITATION = ARXIV:1305.2422;%
Wave functions and correlation functions for GKP strings from integrability
We develop a general method of computing the contribution of the vertex
operators to the semi-classical correlation functions of heavy string states,
based on the state-operator correspondence and the integrable structure of the
system. Our method requires only the knowledge of the local behavior of the
saddle point configuration around each vertex insertion point and can be
applied to cases where the precise forms of the vertex operators are not known.
As an important application, we compute the contributions of the vertex
operators to the three-point functions of the large spin limit of the
Gubser-Klebanov-Polyakov (GKP) strings in spacetime, left unevaluated
in our previous work [arXiv:1110.3949] which initiated such a study. Combining
with the finite part of the action already computed previously and with the
newly evaluated divergent part of the action, we obtain finite three-point
functions with the expected dependence of the target space boundary coordinates
on the dilatation charge and the spin.Comment: 80 pages, 7 figures, v2: typos and minor errors corrected, a
reference added, v3: typos and a reference corrected, published versio
Beyond the Planar Limit in ABJM
In this article we consider gauge theories with a U(N)X U(N) gauge group. We
provide, for the first time, a complete set of operators built from scalar
fields that are in the bi fundamental of the two groups. Our operators
diagonalize the two point function of the free field theory at all orders in
1/N. We then use this basis to investigate non-planar anomalous dimensions in
the ABJM theory. We show that the dilatation operator reduces to a set of
decoupled harmonic oscillators, signaling integrability in a nonplanar large N
limit.Comment: v2: minor revisison
An algebraic approach to the scattering equations
We employ the so-called companion matrix method from computational algebraic geometry, tailored for zero-dimensional ideals, to study the scattering equations. The method renders the CHY-integrand of scattering amplitudes computable using simple linear algebra and is amenable to an algorithmic approach. Certain identities in the amplitudes as well as rationality of the final integrand become immediate in this formalism
Mitochondrial Priming by CD28
T cell receptor (TCR) signaling without CD28 can elicit primary effector T cells, but memory T cells generated during this process are anergic, failing to respond to secondary antigen exposure. We show that, upon T cell activation, CD28 transiently promotes expression of carnitine palmitoyltransferase 1a (Cpt1a), an enzyme that facilitates mitochondrial fatty acid oxidation (FAO), before the first cell division, coinciding with mitochondrial elongation and enhanced spare respiratory capacity (SRC). microRNA-33 (miR33), a target of thioredoxin-interacting protein (TXNIP), attenuates Cpt1a expression in the absence of CD28, resulting in cells that thereafter are metabolically compromised during reactivation or periods of increased bioenergetic demand. Early CD28-dependent mitochondrial engagement is needed for T cells to remodel cristae, develop SRC, and rapidly produce cytokines upon restimulation—cardinal features of protective memory T cells. Our data show that initial CD28 signals during T cell activation prime mitochondria with latent metabolic capacity that is essential for future T cell responses
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation
How cells adapt metabolism to meet demands is an active area of interest across biology. Among a broad range of functions, the polyamine spermidine is needed to hypusinate the translation factor eukaryotic initiation factor 5A (eIF5A). We show here that hypusinated eIF5A (eIF5AH) promotes the efficient expression of a subset of mitochondrial proteins involved in the TCA cycle and oxidative phosphorylation (OXPHOS). Several of these proteins have mitochondrial targeting sequences (MTSs) that in part confer an increased dependency on eIF5AH. In macrophages, metabolic switching between OXPHOS and glycolysis supports divergent functional fates stimulated by activation signals. In these cells, hypusination of eIF5A appears to be dynamically regulated after activation. Using in vivo and in vitro models, we show that acute inhibition of this pathway blunts OXPHOS-dependent alternative activation, while leaving aerobic glycolysis-dependent classical activation intact. These results might have implications for therapeutically controlling macrophage activation by targeting the polyamine-eIF5A-hypusine axis
Flavour singlets in gauge theory as permutations
50 pages, v2: typos corrected, v3: to appear in JHEPJHEP is an open-access journal funded by SCOAP3 and licensed under CC BY 4.
Quivers as calculators: counting, correlators and Riemann surfaces
86 figures (84 pages + Appendices
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