“We are much closer here”: exploring the use of WhatsApp as a learning environment in a secondary school mathematics class

In this study, we examined a mathematics teacher’s communicative acts on an instant messaging tool, WhatsApp, and its role in creating a sustained learning environment between secondary-school students and a teacher in Turkey. The interactions of a mathematics teacher and his students (n = 38) over two years were explored. The WhatsApp group increased interaction in out-of-school hours. Analysis of the teacher’s communicative acts was the leading force that encouraged the group to continue to interact. The teacher portrayed an informal and sincere presentation of himself on social media. A constructive communication style between teacher and students was fostered by connecting through WhatsApp in out-of-school hours, when the teacher’s informal communicative acts have facilitated their learning. © 2021, The Author(s), under exclusive licence to Springer Nature B.V

Semantic Shift to Pragmatic Meaning in Shared Decision Making: Situation Theory Perspective

The way humans establish communication depends on the generation and conveyance of meaning. Linguistically, meaning in information is dependent on the meaning that is ascribed to signifiers in the context of the communication. These signifiers can include items such as words, phrases, signs, and symbols. Conveyance of meaning may, however, imprecise and prone to error. The meaning of information in communication may arise from a change in the context in which a signifier is placed (intrinsic), or a change in the paradigm with which the signifier and context are perceived (extrinsic). In simple situations, where paradigms are reconcilable, semantic shift is solely intrinsic. In complex situations, where differing paradigms will generally lead to irreconcilable perspectives (paradoxes and dualities); the semantic shift will be both intrinsic and extrinsic. Decisions are based on an individual\u27s (or individuals\u27 shared) understanding and understanding is in turn contingent on perspective. Decision making will, therefore, be affected by discrepancies in meaning. It is critical to understand the nature of the discrepancies where shared awareness is necessary to enable group decisions. The theoretical construct presented recognizes that (1) a semantic shift may be required where multiple perspectives based on different paradigms come into play and (2) a semantic shift may introduce error, inefficiency, noise or redundancy. Therefore, individual limits can be recognized via shared awareness, which can be studied with situation theory. © 2015 WIT Press

Subtle pH differences trigger single residue motions for moderating conformations of calmodulin

This study reveals the essence of ligand recognition mechanisms by which calmodulin (CaM) controls a variety of Ca2+ signaling processes. We study eight forms of calcium-loaded CaM each with distinct conformational states. Reducing the structure to two degrees of freedom conveniently describes main features of the conformational changes of CaM via simultaneous twist-bend motions of the two lobes. We utilize perturbation-response scanning (PRS) technique, coupled with molecular dynamics simulations. PRS is based on linear response theory, comprising sequential application of directed forces on selected residues followed by recording the resulting protein coordinates. We analyze directional preferences of the perturbations and resulting conformational changes. Manipulation of a single residue reproduces the structural change more effectively than that of single/pairs/triplets of collective modes of motion. Our findings also give information on how the flexible linker acts as a transducer of binding information to distant parts of the protein. Furthermore, by perturbing residue E31 located in one of the EF hand motifs in a specific direction, it is possible to induce conformational change relevant to five target structures. Independently, using four different pKa calculation strategies, we find this particular residue to be the charged residue (out of a total of 52), whose ionization state is most sensitive to subtle pH variations in the physiological range. It is plausible that at relatively low pH, CaM structure is less flexible. By gaining charged states at specific sites at a pH value around 7, such as E31 found in the present study, local conformational changes in the protein will lead to shifts in the energy landscape, paving the way to other conformational states. These findings are in accordance with Fluorescence Resonance Energy Transfer (FRET) measured shifts in conformational distributions towards more compact forms with decreased pH. They also corroborate mutational studies and proteolysis results which point to the significant role of E31 in CaM dynamics

Comparison of the maternal and neonatal effects of bupivacaine plus fentanyl and ropivacaine plus fentanyl during cesarean delivery

Purpose: The aim of the present study was to compare the anesthetic efficacy, and fetal and maternal effects of 7.5 mg (1 ml) intrathecal 0.75% hyperbaric ropivacaine + 25 ìg (0.5 ml) fentanyl versus 5 mg (l ml) intrathecal 0.5% hyperbaric bupivacaine + 25 ìg (0.5 ml) fentanyl in elective cesarean delivery.Materials and Methods: The study included 40 ASA I–II cases scheduled for cesarean delivery that were randomized into two groups of 20 cases each. Cases in the RF group were administered 0.75% hyperbaric ropivacaine + 25 ìg (0.5 ml) fentanyl and those in the BF group were administered 5 mg (l ml) hyperbaric bupivacaine + 25 ìg (0.5 ml)fentanyl into the spinal space. The time until spinal anesthesia in the T4 dermatome, overall duration of analgesia, hemodynamic parameters, Apgar score of newborns at 1–5 min, fetal blood gas values (pH, PO2, PCO2, HCO3., and BE), maternal side effects, the degree of motor block, maternal need for ephedrine, objective pain scale score, and patient satisfaction were recorded in each group.Results: There were no significant differences between the groups in terms of the parameters evaluated (P > 0.05).Conclusion: In elective cesarean delivery, the combinations of bupivacaine + fentanyl or ropivacaine + fentanyl exhibited similar anesthetic efficacy, and fetal and maternal effects.Key words: Bupivacaine, cesarean, opioid, ropivacain

Agency Theory and Corporate Governance in China: A Meta-Analysis

Do agency theory-based “good corporate governance” principles indeed apply to China? A straightforward answer to this question is lacking, because evidence is inconclusive across studies. We endeavor to fill this gap by conducting the first meta-analysis on the China literature with two focuses. First, we assess the impact of (i) board independence, (ii) board leadership structure, and (iii) managerial incentives on firm performance, as these elements have been central to both agency theory as well as to Chinese corporate governance reforms. Second, we extend current theorizing by showing support for the temporal hypothesis, which states that over time, with the improvement in the quality of market institutions and development of financial markets, the monitoring mechanisms become more important whereas the incentive mechanisms lose their significance. In conclusion, in the world’s second-largest economy, agency theory is not only applicable but is also found to be more strongly supported than in its original context

Double Spin Asymmetries of Inclusive Hadron Electroproduction From a Transversely Polarized He-3 Target

We report the measurement of beam-target double spin asymmetries (ALT) in the inclusive production of identified hadrons, →e + 3He↑ → h + X, using a longitudinally polarized 5.9-GeV electron beam and a transversely polarized 3He target. Hadrons (π±, K±, and proton) were detected at 16 ° with an average momentum ( Ph ) = 2.35 GeV/c and a transverse momentum (pT) coverage from 0.60 to 0.68 GeV/c. Asymmetries from the He-3 target were observed to be nonzero for π± production when the target was polarized transversely in the horizontal plane. The π+ and π- asymmetries have opposite signs, analogous to the behavior of ALT in semi-inclusive deep-inelastic scattering

A New Approach to Learning How to Teach: medical students as instructional designers

As students at the David Geffen School of Medicine at UCLA, the student authors were given the opportunity to develop their own creative projects which would be used to teach future medical students. They chose their own topics, planned and researched their projects, and then implemented the projects in interactive digital Adobe Flash files. In the first project they created interactive case-based radiology teaching files. In the second project they integrated photographic images into the existing illustrative anatomy files. Students in subsequent years have learned from these files on computers both at home and in the school's anatomy lab. The experience of creating the files served as an opportunity for hands-on learning for the student authors, both of the material and of the practice of teaching. In this paper they describe why they undertook these projects, what exactly they did, and the impact their creation had on them. The projects demonstrate that student-driven educational materials are both possible and beneficial. Furthermore, their experience has allowed them to conclude that faculty at other medical schools should consider providing students with opportunities to develop their own creative projects that contribute to the curriculum

Precision Measurement of the Neutron Twist-3 Matrix Element d(2)(n): Probing Color Forces

Double-spin asymmetries and absolute cross sections were measured at large Bjorken x (0.25 ≤ x ≤ 0.90), in both the deep-inelastic and resonance regions, by scattering longitudinally polarized electrons at beam energies of 4.7 and 5.9 GeV from a transversely and longitudinally polarized 3He target. In this dedicated experiment, the spin structure function g(2)(3He) was determined with precision at large x, and the neutron twist-3 matrix element d(2)(n) was measured at \u3c Q2\u3e of 3.21 and 4.32 GeV2/c2, with an absolute precision of about 10-5. Our results are found to be in agreement with lattice QCD calculations and resolve the disagreement found with previous data at \u3c Q2\u3e = 5 GeV2/c2. Combining d(2)(n) and a newly extracted twist-4 matrix element f(2)(n), the average neutron color electric and magnetic forces were extracted and found to be of opposite sign and about 30 MeV/fm in magnitude