Granulomatous pyoderma preceding chronic recurrent multifocal osteomyelitis triggered by vaccinations in a two-year-old boy: a case report

<p>Abstract</p> <p>Introduction</p> <p>Chronic recurrent multifocal osteomyelitis is a rare, systemic, aseptic, inflammatory disorder that involves different sites. Pathogenesis of chronic recurrent multifocal osteomyelitis is currently unknown.</p> <p>Case presentation</p> <p>A two-year-old Caucasian boy, diagnosed with chronic recurrent multifocal osteomyelitis with granulomatous pyoderma following routine vaccinations is presented for the first time in the literature.</p> <p>Conclusion</p> <p>We conclude that antigen exposures might have provoked this inflammatory condition for our case. Skin and/or bone lesions following vaccinations should raise suspicion of an inflammatory response such as chronic recurrent multifocal osteomyelitis only after thorough evaluation for chronic infection, autoimmune, immunodeficiency or vasculitic diseases.</p

Grain and seed protein functionality

Editado por Jiménez-López, José Carlos (CSIC

Steroid utilization in eosinophilic jejunitis: Beneficial or harmful?

PubMed ID: 19418064Purpose: Eosinophilic jejunitis is a rare disorder of undetermined origin, which is characterized by infiltration of eosinophils in the intestine. The aim of this study is to evaluate steroid therapy effect in patient treated for eosinophilic jejunitis to share our experience with other colleagues. Methods: We report a patient with symptoms of small bowel obstruction whose diagnosis was confirmed by previous operation owing to a well-known pathology due to an unusual reason, perforation, which was masqueraded by therapeutic drugs. Result: This clinical entity is usually encountered between the third and fifth decades. Stomach and small intestine are the most affected organs; however, it can affect any part of the gastrointestinal system. Abdominal pain and obstructive symptoms concomitant with weight loss are the common presenting complaints. According to current knowledge, avoiding unnecessary resection unless it is inevitable is an acceptable option for the management of eosinophilic jejunitis disease. Conclusion: Recent data suggest that eosinophils may directly damage the gastrointestinal tract wall in eosinophilic gastroenteritis. A few limited literatures about this disease strongly recommends steroid therapy for treatment. Furthermore, beneficial or harmful effects of steroids in eosinophilic jejunitis and its treatment details are discussed and reviewed. © 2009 Springer-Verlag

Unexpected Benefit of the Positron Emission Tomography/Computed Tomography Using F-18-Fluorodeoxyglucose: Report of a Case

WOS: 000389341300002PubMed ID: 27994328The positron emission tomography/computed tomography (PET/CT) has been a new tool utilized in the diagnosis and staging of various cancers. However, common worldwide utilization of the PET/CT includes some economic, legal, and ethic controversies. Although PET/CT scanning can detect colorectal premalignant lesions in an early treatable stage, most governments' health care system does not pay for it as a screening test because of its economic burden. Thus, people are forced to make vital decisions about their health because of health policies of their governments. Here, we present an unusual case and discuss the utilization of PET/CT for detection of incidental neoplasms