Case report of an exercise training and nutritional intervention plan in a patient with A350P mutation in DES gene.

Performing a supplementation intervention with creatine and protein, in conjunction with low-intensity endurance and resistance exercise is safe and has a positive effect on the quality of life in a patient with desminopathy

Case report of an exercise training and nutritional intervention plan in a patient with A350P mutation in DES gene.

Performing a supplementation intervention with creatine and protein, in conjunction with low-intensity endurance and resistance exercise is safe and has a positive effect on the quality of life in a patient with desminopathy

Effects of A High Intensity Interval Session on Mucosal Immune Function and Salivary Hormones in Male and Female Endurance Athletes.

Although the effects of high intensity interval training (HIIT) on health and sports performance are well documented, the effects of this training type on mucosal immune function remain unclear. The aim of this study was to assess the impact of an acute HIIT session on salivary immune and endocrine marker levels (immunoglobulin A (sIgA), alpha amylase (sAA), cortisol (C), and testosterone (T)) in male and female endurance athletes. Twenty subjects (ten males and ten females) underwent ten bouts of treadmill running using a 4 min:2 min work:rest ratio at ~90% of peak oxygen uptake (VO). Saliva samples were collected 5 min before and 20 min post-exercise. During work intervals, female participants had a higher HR than male participants (+4.0 ± 5%; p = 0.008). Rating of perceived exertion (RPE) increased throughout the duration of the HIIT session in both males and females (main time effect: p < 0.001), but was higher in males than females (+17 ± 4%; time x gender main effect: p < 0.001). Lactate concentrations were similar in both males and females. Exercise increased the concentration of salivary IgA (males: +24 ± 6%, p = 0.004; females: +27 ± 3%, p = 0.03), salivary alpha-amylase (males: +44 ± 22%, p = 0.036; females: +71 ± 26%, p = 0.026) and salivary cortisol (males: +41 ± 24%, p = 0.015; females: +55 ± 24%, p = 0.005). Testosterone levels and the Testosterone/Cortisol ratio remained stable in both males and females. These findings suggest that the physiological stress produced by a HIIT session does not affect immune function and does not disturb the anabolic/catabolic balance

Basal Mild Dehydration Increase Salivary Cortisol After a Friendly Match in Young Elite Soccer Players

A soccer match induce changes in physiological stress biomarkers as testosterone (T), cortisol (C), and testosterone:cortisol (T:C) ration. Hydration state may also modulate these hormones, and therefore may alter the anabolic/catabolic balance in response to soccer match. The role of hydration status before the match in this biomarkers has not yet been reported. The aim of this study was to compare the salivary T, C, and the T:C ratio responses after two friendly matches in well-hydrated and mild-dehydrated (MD) elite young male soccer player. Seventeen players (age, 16.8 ± 0.4 years; VO2max 57.2 ± 3.6 ml/kg−1/min−1) were divided into two teams. Before the matches the athletes were assessed for hydration level by the urine specific gravity method and divided for the analysis into well-hydrated (WH; n = 9; USG &lt; 1.010 g/mL−1) and mild-dehydrated (MD; n = 8; USG 1.010 to 1.020 g/mL−1) groups. Hormones were collected before and after each match by saliva samples. The mean (HRmean) and maximal (HRmax) heart rate were measured throughout the matches. A two-way ANOVA was used to compare T, C, and T:C between and within groups. Similar HRmean (WH, 83.1 ± 4.7%; MD, 87.0 ± 4.1; p = 0.12) and HRmax (WH, 93.2 ± 4.4%; MD, 94.7 ± 3.7%; p = 0.52) were found for both groups during the matches. No differences were found before the matches in the T (p = 0.38), C (p = 66), nor T:C (p = 0.38) between groups. No changes within groups were found after matches in neither group for T (WH, p = 0.20; MD, p = 0.36), and T:C (WH, p = 0.94; MD, p = 0.63). Regarding the C, only the MD group showed increases (28%) after the matches (MD, p = 0.03; WH, p = 0.13). In conclusion MD group exacerbate the C response to friendly matches in elite young male soccer players, suggesting that dehydration before match may be an added stress to be considered

Análisis preliminar del efecto de la edad y la escolaridad en adultos sanos en el rendimiento del Sydney Language Battery (Sydbat) en español de Chile

There are 3 variants of primary progressive aphasia (APP), which are distinguished according to the predominantly altered linguistic domain: non-fluent, logopenic, and semantic. A tool that helps in its classification is the Sydney Language Battery (Sydbat), which is not validated in Chile. The objective of this work is to analyze the possible relationship between age, years of schooling and performance obtained in the Sydbat subtests in healthy adults. 38 healthy adults participated in the test. The average age was 56.8 years (SD = 8.3) and they had a mean of 13.8 years of schooling (SD = 3.9). They all came from the Metropolitan Region. Pearson and Spearman correlations were performed to explore the correlation between subtest performance, age, and schooling. Considering the variability in performance in the subtests, univariate and multivariate models were performed. Significant correlations were found between age and the comprehension subtest (pExisten 3 variantes de afasia progresiva primaria (APP), que se distinguen según el dominio lingüístico predominantemente alterado: no fluente, logopénica y semántica. Una herramienta que ayuda a su clasificación es el Sydney Language Battery (Sydbat), el cual no se encuentra validado en Chile. El objetivo del presente trabajo es analizar la posible relación entre edad, años de escolaridad y rendimiento obtenido en las subpruebas del Sydbat en adultos sanos. Participaron 38 adultos sanos a los que se les aplicó el test. El promedio de edad fue 56,8 años (DE = 8,3) y tenían una media de 13,8 años de escolaridad (DE = 3,9). Todos provenían de la Región Metropolitana. Se realizaron correlaciones de Pearson y Spearman, para explorar la correlación entre el rendimiento en las subpruebas, la edad y la escolaridad. Considerando la variabilidad en el rendimiento en las subpruebas, se realizaron modelos uni y multivariados. Se encontraron correlaciones significativas entre edad y la subprueba comprensión (