5,026 research outputs found

    Reply - Aortic Reservoir Pressure - not overstretching but testing

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    Is Injury an Occupational Hazard for Horseracing Staff?

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    Occupational health is a key priority for the horseracing industry, yet little research on occupational injuries exists. This study investigated the prevalence and the effect of injury in British horseracing staff during a 12-month period. An online retrospective survey was answered by 352 participants, identifying self-reported injury prevalence, injury management practices and attitudes towards workplace injury reporting. Chi Squared tests for independence were undertaken. A total of 310 (88.1%) staff reported injuries; risk factors for injury type included self-perceived job security, working hours, and perceived job control. Physical limitations, loss of confidence, workplace changes, and lifestyle implications were reported as consequences of injury. A total of 75.3% (n = 134) of staff were likely to seek time-off following fractures, but only 48.6% (n = 86) would take time-off for concussion. Attitudes towards injury management were influenced by financial circumstances, perceived staff shortages, previous injury experiences, and perceived employer expectations. The high self-reported injury prevalence could result in decreased workforce efficiency, poor physical health, and negative implications on retention and career longevity. The perception of invisible injuries, i.e., concussion, and subsequent management, should be of immediate concern to racing organizations. This paper identifies recommendations to enhance the safety and wellbeing of horseracing staff

    Dynamo Processes in the T Tauri star V410 Tau

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    We present new brightness and magnetic images of the weak-line T Tauri star V410 Tau, made using data from the NARVAL spectropolarimeter at Telescope Bernard Lyot (TBL). The brightness image shows a large polar spot and significant spot coverage at lower latitudes. The magnetic maps show a field that is predominantly dipolar and non-axisymmetric with a strong azimuthal component. The field is 50% poloidal and 50% toroidal, and there is very little differential rotation apparent from the magnetic images. A photometric monitoring campaign on this star has previously revealed V-band variability of up to 0.6 magnitudes but in 2009 the lightcurve is much flatter. The Doppler image presented here is consistent with this low variability. Calculating the flux predicted by the mapped spot distribution gives an peak-to-peak variability of 0.04 magnitudes. The reduction in the amplitude of the lightcurve, compared with previous observations, appears to be related to a change in the distribution of the spots, rather than the number or area. This paper is the first from a Zeeman-Doppler imaging campaign being carried out on V410 Tau between 2009-2012 at TBL. During this time it is expected that the lightcurve will return to a high amplitude state, allowing us to ascertain whether the photometric changes are accompanied by a change in the magnetic field topology.Comment: 12 pages, 11 figures, accepted by MNRA

    Automatic correction of hand pointing in stereoscopic depth

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    In order to examine whether stereoscopic depth information could drive fast automatic correction of hand pointing, an experiment was designed in a 3D visual environment in which participants were asked to point to a target at different stereoscopic depths as quickly and accurately as possible within a limited time window (≤300 ms). The experiment consisted of two tasks: "depthGO" in which participants were asked to point to the new target position if the target jumped, and "depthSTOP" in which participants were instructed to abort their ongoing movements after the target jumped. The depth jump was designed to occur in 20% of the trials in both tasks. Results showed that fast automatic correction of hand movements could be driven by stereoscopic depth to occur in as early as 190 ms.This work was supported by the Grants from the National Natural Science Foundation of China (60970062 and 61173116) and the Doctoral Fund of Ministry of Education of China (20110072110014)

    Fibrin Glue Acutely Blocks Distal Muscle Contraction after Confirmed Polyethylene Glycol Nerve Fusion: An Animal Study.

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    BACKGROUND: Polyethylene glycol (PEG) is a synthetic, biodegradable, and hyperosmotic material promising in the treatment of acute peripheral nerve injuries. Our team set out to investigate the impact of fibrin glue upon PEG fusion in a rat model. METHODS: Eighteen rats underwent sciatic nerve transection and PEG fusion. Electrophysiologic testing was performed to measure nerve function and distal muscle twitch. Fibrin glue was applied and testing repeated. Due to preliminary findings, fibrin glue was applied to an uncut nerve in five rodents and testing was conducted before and after glue application. Mann-Whitney U tests were used to compare median values between outcome measures. A Shapiro-Wilk test was used to determine normality of data for each comparison, significance set at a P value less than 0.05. RESULTS: PEG fusion was confirmed in 13 nerves with no significant change in amplitude (P \u3c 0.001), and conduction velocity (P = 0.023). Stimulation of the nerve after application of fibrin glue did not produce distal muscle twitch. Five uncut nerves with fibrin glue application blocked distal muscle contraction following stimulation. CONCLUSIONS: Our data suggest that fibrin glue alters the nerve\u27s function. The immediate confirmation of PEG fusion via distal muscle twitch is blocked with application fibrin glue in this experimental model. Survival and functional outcome studies are necessary to understand if this has implications on the long-term functional outcomes

    Mechanical equilibrium of hot, large‐scale magnetic loops on T Tauri stars

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    The most extended, closed magnetic loops inferred on T Tauri stars confine hot, X‐ray‐emitting plasma at distances from the stellar surface beyond the X‐ray‐bright corona and closed large‐scale field, distances comparable to the corotation radius. Mechanical equilibrium models have shown that dense condensations, or ‘slingshot prominences’, can rise to great heights due to their density and temperatures cooler than their environs. On T Tauri stars, however, we detect plasma at temperatures hotter than the ambient coronal temperature. By previous model results, these loops should not reach the inferred heights of tens of stellar radii where they likely no longer have the support of the external field against magnetic tension. In this work, we consider the effects of a stellar wind and show that indeed hot loops that are negatively buoyant can attain a mechanical equilibrium at heights above the typical extent of the closed corona and the corotation radius.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90589/1/j.1365-2966.2012.20434.x.pd

    Ex vivo culture of adult CD34+ stem cells using functional highly porous polymer scaffolds to establish biomimicry of the bone marrow niche

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    Haematopoiesis, the process of blood production, occurs from a tiny contingent of haematopoietic stem cells (HSC) in highly specialised three-dimensional niches located within the bone marrow. When haematopoiesis is replicated using in vitro two-dimensional culture, HSCs rapidly differentiate, limiting self-renewal. Emulsion-templated highly porous polyHIPE foam scaffolds were chosen to mimic the honeycomb architecture of human bone. The unmodified polyHIPE material supports haematopoietic stem and progenitor cell (HSPC) culture, with successful culture of erythroid progenitors and neutrophils within the scaffolds. Using erythroid culture methodology, the CD34+ population was maintained for 28 days with continual release of erythroid progenitors. These cells are shown to spontaneously repopulate the scaffolds, and the accumulated egress can be expanded and grown at large scale to reticulocytes. We next show that the polyHIPE scaffolds can be successfully functionalised using activated BM(PEG)2 (1,8-bismaleimido-diethyleneglycol) and then a Jagged-1 peptide attached in an attempt to facilitate notch signalling. Although Jagged-1 peptide had no detectable effect, the BM(PEG)2 alone significantly increased cell egress when compared to controls, without depleting the scaffold population. This work highlights polyHIPE as a novel functionalisable material for mimicking the bone marrow, and also that PEG can influence HSPC behaviour within scaffolds

    Searching for New Physics Through AMO Precision Measurements

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    We briefly review recent experiments in atomic, molecular, and optical physics using precision measurements to search for physics beyond the Standard Model. We consider three main categories of experiments: searches for changes in fundamental constants, measurements of the anomalous magnetic moment of the electron, and searches for an electric dipole moment of the electron.Comment: Prepared for Comments on AMO Physics at Physica Script

    Helioseismology of Sunspots: A Case Study of NOAA Region 9787

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    Various methods of helioseismology are used to study the subsurface properties of the sunspot in NOAA Active Region 9787. This sunspot was chosen because it is axisymmetric, shows little evolution during 20-28 January 2002, and was observed continuously by the MDI/SOHO instrument. (...) Wave travel times and mode frequencies are affected by the sunspot. In most cases, wave packets that propagate through the sunspot have reduced travel times. At short travel distances, however, the sign of the travel-time shifts appears to depend sensitively on how the data are processed and, in particular, on filtering in frequency-wavenumber space. We carry out two linear inversions for wave speed: one using travel-times and phase-speed filters and the other one using mode frequencies from ring analysis. These two inversions give subsurface wave-speed profiles with opposite signs and different amplitudes. (...) From this study of AR9787, we conclude that we are currently unable to provide a unified description of the subsurface structure and dynamics of the sunspot.Comment: 28 pages, 18 figure
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