UR-347 Blockchain in Ethereum

Earthereum is a cryptocurrency token built on the Ethereum blockchain utilizing an ERC-20 contract and implemented with Solidity in Remix and deploying using MetaMask. The mission of Earthereum is developing an ecologically-friendly utility for cryptocurrencies

Cell Division Resets Polarity and Motility for the Bacterium Myxococcus xanthus

Links between cell division and other cellular processes are poorly understood. It is difficult to simultaneously examine division and function in most cell types. Most of the research probing aspects of cell division has experimented with stationary or immobilized cells or distinctly asymmetrical cells. Here we took an alternative approach by examining cell division events within motile groups of cells growing on solid medium by time-lapse microscopy. A total of 558 cell divisions were identified among approximately 12,000 cells. We found an interconnection of division, motility, and polarity in the bacterium Myxococcus xanthus. For every division event, motile cells stop moving to divide. Progeny cells of binary fission subsequently move in opposing directions. This behavior involves M. xanthus Frz proteins that regulate M. xanthus motility reversals but is independent of type IV pilus “S motility.” The inheritance of opposing polarity is correlated with the distribution of the G protein RomR within these dividing cells. The constriction at the point of division limits the intracellular distribution of RomR. Thus, the asymmetric distribution of RomR at the parent cell poles becomes mirrored at new poles initiated at the site of division

Prison Gerrymandering Report 2021

The purpose of the redistricting process should be to create districts that accurately reflect the communities they represent and to distribute political power across those communities. But counting incarcerated individuals at the facility where they are incarcerated, rather than their home addresses, artificially bolsters the political power of certain communities on the backs of individuals who are not truly part of those communities, while simultaneously reducing the political voices of their home communities. In Texas, there are dramatic implications, with a handful of rural regions gaining a disproportionate share of the political power over other rural regions and diminishing the true population count in certain urban areas. This under-representation only exacerbates existing problems with Census undercounts and socio economic disparities which have a root in racial discrimination. It also deviates from how Texas law treats incarcerated populations in every other context, creating a conflict with the Texas constitution that needs to be addressed.Traditionally, the United States Census Bureau has counted incarcerated individuals at the facility where they are housed, but the Bureau has made clear that this historical practice has persisted only for administrative reasons, not for legal or policy ones. Recently, the Census Bureau has evolved in its treatment of incarcerated populations, and, for the first time, will make it practical for states on tight timelines to assign incarcerated individuals to their home communities. Many states across the nation are taking advantage of this opportunity to correct for the distortions created by prison gerrymandering. In order to more accurately reflect the state's population, Texas legislators should take advantage of the Census Bureau's new tools and work with state agencies to identify those prisoners who, rightfully, should be counted at an address in their permanent community

One Versus Two Handedness: Directional Preference in a Silent-Failure Scenario

This study focused on the direction drivers of a self-driving car will turn to avoid a crash at a T-intersection. We hypothesized that drivers would steer differently when they drive using both hands and when they use their dominant hand only. Specifically, we hypothesized that participants would favor the direction of their dominant hand (if they use their dominant hand only) and that there with be no directional preference if driving with both hands.. To test this hypothesis, we implemented a driving simulator study. We asked the participants to use either both their hands or only their dominant hand to avoid a crash. We are currently analyzing the data. Keywords: one-handed, two-handed, automated vehicle, silent takeover, directional preferenc

Modeling multiple ecosystem services, biodiversity conservation, commodity production, and tradeoffs at landscape scales

Nature provides a wide range of benefits to people. There is increasing consensus about the importance of incorporating these ecosystem services into resource management decisions, but quantifying the levels and values of these services has proven difficult. We use a spatially explicit modeling tool, Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST), to predict changes in ecosystem services, biodiversity conservation, and commodity production levels. We apply InVEST to stakeholder-defined scenarios of land-use/land-cover change in the Willamette Basin, Oregon. We found that scenarios that received high scores for a variety of ecosystem services also had high scores for biodiversity, suggesting there is little tradeoff between biodiversity conservation and ecosystem services. Scenarios involving more development had higher commodity production values, but lower levels of biodiversity conservation and ecosystem services. However, including payments for carbon sequestration alleviates this tradeoff. Quantifying ecosystem services in a spatially explicit manner, and analyzing tradeoffs between them, can help to make natural resource decisions more effective, efficient, and defensible. © The Ecological Society of America

Type IV pili interactions promote intercellular association and moderate swarming of Pseudomonas aeruginosa

Pseudomonas aeruginosa is a ubiquitous bacterium that survives in many environments, including as an acute and chronic pathogen in humans. Substantial evidence shows that P. aeruginosa behavior is affected by its motility, and appendages known as flagella and type IV pili (TFP) are known to confer such motility. The role these appendages play when not facilitating motility or attachment, however, is unclear. Here we discern a passive intercellular role of TFP during flagellar-mediated swarming of P. aeruginosa that does not require TFP extension or retraction. We studied swarming at the cellular level using a combination of laboratory experiments and computational simulations to explain the resultant patterns of cells imaged from in vitro swarms. Namely, we used a computational model to simulate swarming and to probe for individual cell behavior that cannot currently be otherwise measured. Our simulations showed that TFP of swarming P. aeruginosa should be distributed all over the cell and that TFP−TFP interactions between cells should be a dominant mechanism that promotes cell−cell interaction, limits lone cell movement, and slows swarm expansion. This predicted physical mechanism involving TFP was confirmed in vitro using pairwise mixtures of strains with and without TFP where cells without TFP separate from cells with TFP. While TFP slow swarm expansion, we show in vitro that TFP help alter collective motion to avoid toxic compounds such as the antibiotic carbenicillin. Thus, TFP physically affect P. aeruginosa swarming by actively promoting cell-cell association and directional collective motion within motile groups to aid their survival.National Institutes of HealthIndiana Clinical and Translational Sciences Institut

No Evidence That Salt Water Ingestion Kills Adult Mosquitoes (Diptera: Culicidae)

Various products and insecticides are available that purport to reduce wild populations of adult mosquitoes. Recently, several manufacturers and general public comments on the internet have promoted devices that claim that ingestion of salt will significantly reduce populations of wild mosquitoes to near zero; there are no known scientific efficacy data that support these claims. We tested the survival of nine mosquito species of pest and public health importance across four adult diets: Water Only, Sugar Water Only (8.00%), Salt Water Only (1.03%), and Sugar + Salt Water. Species included the following: Aedes aegypti (L.), Aedes albopictus (Skuse), Aedes dorsalis (Meigen), Aedes notoscriptus (Skuse), Aedes vigilax (Skuse), Anopheles quadrimaculatus (Say), Culex pipiens (L.), Culex quinquefasciatus (Say), and Culex tarsalis (Coquillett). Male and female mosquitoes were placed in cages and allowed to feed on liquid diets under controlled environmental conditions for 1 wk. For seven of the nine species, adult survival was significantly higher in the presence (Sugar Water, Sugar + Salt Water) versus the absence (Water Only, Salt Only) of sugar, with no indication that salt had any effect on survival. Anopheles quadrimaculatus showed intermediate survival in Sugar + Salt to either Sugar Only or no sugar diets, whereas Aedes dorsalis showed low survival in Salt Only versus other diets. Based on our data and coupled with the fact that mosquitoes have physiological and behavioral adaptations that allow them to avoid or process excess salt (as found in blood meals), we conclude that there is no scientific foundation for salt-based control methods of mosquitoes