2,188 research outputs found
Bank Of Holly Springs, Holly Springs, Miss.
https://egrove.olemiss.edu/ms_pcards/1089/thumbnail.jp
High Energy Physics from High Performance Computing
We discuss Quantum Chromodynamics calculations using the lattice regulator.
The theory of the strong force is a cornerstone of the Standard Model of
particle physics. We present USQCD collaboration results obtained on Argonne
National Lab's Intrepid supercomputer that deepen our understanding of these
fundamental theories of Nature and provide critical support to frontier
particle physics experiments and phenomenology.Comment: Proceedings of invited plenary talk given at SciDAC 2009, San Diego,
June 14-18, 2009, on behalf of the USQCD collaboratio
Building Brains for Bodies
We describe a project to capitalize on newly available levels of computational resources in order to understand human cognition. We will build an integrated physical system including vision, sound input and output, and dextrous manipulation, all controlled by a continuously operating large scale parallel MIMD computer. The resulting system will learn to "think'' by building on its bodily experiences to accomplish progressively more abstract tasks. Past experience suggests that in attempting to build such an integrated system we will have to fundamentally change the way artificial intelligence, cognitive science, linguistics, and philosophy think about the organization of intelligence. We expect to be able to better reconcile the theories that will be developed with current work in neuroscience
Hawking radiation and thermodynamics of dynamical black holes in phantom dominated universe
The thermodynamic properties of dark energy-dominated universe in the
presence of a black hole are investigated in the general case of a varying
equation-of-state-parameter . We show that all the thermodynamics
quantities are regular at the phantom divide crossing, and particularly the
temperature and the entropy of the dark fluid are always positive definite. We
also study the accretion process of a phantom fluid by black holes and the
conditions required for the validity of the generalized second law of
thermodynamics. As a results we obtain a strictly negative chemical potential
and an equation-of-state parameter Comment: 22 pages,3 figure
Further education improves cognitive reserve and triggers improvement in selective cognitive functions in older adults: The Tasmanian Healthy Brain Project
Introduction The strong link between early-life education and subsequent reduced risk of dementia suggests that education in later life could enhance cognitive function and may reduce age-related cognitive decline and protect against dementia. Methods Episodic memory, working memory, executive function, and language processing performances were assessed annually over 4 years in 359 healthy older adults who attended university for a minimum of 12 months (intervention) and were compared against 100 healthy adult controls. Results Multiple group latent growth curve modeling revealed a significant improvement in language processing capacity over time in the intervention group. No changes were detected for episodic memory, working memory, or executive function. Discussion These results suggest that complex mental stimulation resulting from late-life further education results in improved crystallized knowledge but no changes to fluid cognitive functions. Ā© 2017 The Author
Ex post aggregate real rates of return in Canada: 1947-1976
Cover title"June 1981."Series statement handwritten on cover"This is a draft of a study to be published by the Economic Council of Canada. It is made available to participants in the Rates of Return Conference on the strict understanding that it is not to be circulated or quoted without permission from the Economic Council of Canada."Includes bibliographical references (p. 77-80
B cell phenotypes in patients with rheumatoid arthritis relapsing after rituximab: expression of B cell-activating factor-binding receptors on B cell subsets
Serum levels of B cellāactivating factor (BAFF) rise following rituximab (RTX) therapy in patients with rheumatoid arthritis (RA). Initiation of naive B cell return to the periphery and autoreactive B cell expansion leading to relapse after RTX may therefore be linked to interactions between BAFF and BAFFābinding receptors (BBR). Relationships between serum BAFF and BBR expression [(BAFFR, calcium signal modulating cyclophilic ligand interactor (TACI) and B cell maturation antigen (BCMA)] were determined on B cell subsets, defined using immunoglobulin (Ig)D/CD38. Twenty preāRTX and 18 RA patients relapsing after B cell depletion were included. Results were analysed with respect to timing of relapse up to 7 months after peripheral B cell return (ā„ 5 B cells/Ī¼l) and to serum BAFF levels. After B cell return, B cell populations from relapsing patients had significantly lower BAFFR+ expression compared to HC and preāRTX patients. The percentage of BAFFR+ B cells increased with time after B cell return and was correlated inversely with serum BAFF levels. BAFFR expression remained reduced. The percentage of TACI+ memory B cells were lower in RA patients after RTX compared with healthy controls (HC). BCMA expression (% and expression) did not differ between patients and HC. Relapse following B cell return appeared largely independent of the percentage of BAFFR+ or percentage of BCMA+ B cells or serum BAFF levels. The lower percentage of TACI+ memory B cells may reduce inhibitory signalling for B cell differentiation. In patients relapsing at longer periods after B cell return, recovery of the B cell pool was more complete, suggesting that selection or expansion of autoreactive B cells may be needed to precipitate relapse
Does the Cambridge Automated Neuropsychological Test Battery (CANTAB) Distinguish Between Cognitive Domains in Healthy Older Adults?
The Cambridge Neuropsychological Test Automated Battery (CANTAB) is a semiautomated computer interface for assessing cognitive function. We examined whether CANTAB tests measured specific cognitive functions, using established neuropsychological tests as a reference point. A sample of 500 healthy older (M = 60.28 years, SD = 6.75) participants in the Tasmanian Healthy Brain Project completed battery of CANTAB subtests and standard paper-based neuropsychological tests. Confirmatory factor analysis identified four factors: processing speed, verbal ability, episodic memory, and working memory. However, CANTAB tests did not consistently load onto the cognitive domain factors derived from traditional measures of the same function. These results indicate that five of the six CANTAB subtests examined did not load onto single cognitive functions. These CANTAB tests may lack the sensitivity to measure discrete cognitive functions in healthy populations or may measure other cognitive domains not included in the traditional neuropsychological battery
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