¿El bilingüismo como protección ante la demencia? Inconsistencias empíricas y nuevas propuestas metodológicas

El deterioro cognitivo durante el envejecimiento normal o patológico puede retrasarse mediante experiencias que fomentan la reserva cognitiva. En este sentido, algunos estudios indican que el bilingüismo retrasaría los síntomas de la enfermedad de Alzheimer. Sin embargo, la evidencia se basa en diseños retrospectivos que arrojan resultados contradictorios. Este trabajo analiza dichos resultados, identifica las principales variables detrás de sus discrepancias y propone alternativas metodológicas. Primero, caracterizamos los posibles factores de confusión, a saber: criterios para definir el bilingüismo, diferencias en los diseños muestrales, instrumentos empleados para estudiar las habilidades cognitivas y variables que modulan el desempeño cognitivo. Luego proponemos que estas limitaciones se podrían evitar mediante diseños experimentales y el uso de instrumentos adecuados para controlar eficazmente dichas variables. Además, sugerimos incorporar tareas que ya han demostrado patrones predecibles de desempeño contrastivo entre individuos bilingües y monolingües (desventajas bilingües en el vocabulario, efectos nulos en ciertos componentes de la memoria de trabajo y ventajas en el control inhibitorio), y otras que podrían sumar datos muy valiosos (como las tareas de interferencia proactiva). Estas consideraciones pueden arrojar luz no sólo sobre la relación entre bilingüismo y reserva cognitiva, sino también sobre mecanismos más generales de compensación cognitiva.Bilingualism and cognitive reserve: empirical inconsistencies and new methodological proposals. Cognitive decline throughout healthy or pathological aging can be slowed down by experiences which foster cognitive reserve. In this sense, some studies have suggested that bilingualism may delay the onset of Alzheimer’s disease. However, the evidence stems from retrospective approaches yielding contradictory results. The present paper addresses these findings, identifies possible lurking variables, and outlines methodological alternatives thereof. First, we characterize possible confounding factors, namely: the criteria to establish bilingualism, differences in sample design, the instruments used to examine cognitive skills, and variables known to modulate life-long cognition. Second, we propose that these limitations could be largely circumvented through experimental approaches and the use of adequate instruments to measure such variables. Moreover, future research should incorporate tasks yielding predictable patterns of contrastive performance between bilinguals and monolinguals (bilingual disadvantages in vocabulary, null effects in working memory, advantages in inhibitory control and other executive functions), and other which could offer valuable insights (e. g., proactive interference tasks). Such considerations may shed light not just on the relationship between bilingualism and cognitive reserve, but also on more general mechanisms of cognitive compensation.Fil: Calvo Garbarino, Noelia Belén. Universidad Nacional de Córdoba. Facultad de Psicología; Argentina. Universidad Nacional de San Juan. Facultad de Filosofía, Humanidades y Artes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Manoiloff, Laura Maria Victoria. Universidad Nacional de Córdoba. Facultad de Psicología; ArgentinaFil: Muñoz, Edison. Universidad de Santiago de Chile. Facultad de Humanidades; ChileFil: Contreras, Marcela. Universidad de Santiago de Chile. Facultad de Humanidades; ChileFil: Ibáñez Barassi, Agustín Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Cuyo; Argentina. Universidad Adolfo Ibañez; Chile. Universidad Autónoma del Caribe; ColombiaFil: García, Adolfo Martín. Instituto de Neurología Cognitiva. Laboratorio de Psicología Experimental y Neurociencia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentin

Commentary: Attentional control and the self: The Self-Attention Network (SAN)

The Self-Attention Network (SAN) model (Humphreys & Sui, 2015) is a recent neurocognitive model to account for self-biases in the allocation of attention. It emerges from psychological, neuropsychological, and neuroimaging evidence on three phenomena: own-name effects, own-face effects, and self-biases in associative matching. Specifically, it posits that our responses to self-related stimuli are differentially subserved by a network comprising three nodes: (i) a general-purpose top-down attentional control network which involves the dorsolateral prefrontal cortex and the intra-parietal sulcus; (ii) a self-representation hub located in the ventromedial prefrontal cortex (vmPFC), and (iii) a bottom-up orientating mechanism which depends on the posterior superior temporal sulcus (pSTS). Accordingly, attentional shifts upon hearing our own name or seeing our own face would rely on interactions among such nodes, mimicking perceptual-saliency effects and determining emergent behavior.Though attractive, this proposal features two major caveats. First, the evidence for own-name effects is inconsistent and undermined by psycholinguistic confounds. Second, the node proposed to subserve self-specific information lacks neurofunctional specificity. Here we discuss both issues and advance relevant methodological recommendations.Fil: García, Adolfo Martín. Universidad Nacional de Cuyo. Facultad de Educación Elemental y Especial; Argentina. Universidad Diego Portales; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Huepe, David. Universidad Diego Portales; ChileFil: Martínez Pernía, David. Universidad Diego Portales; ChileFil: Morales, Juan P.. Universidad Diego Portales; ChileFil: Huepe, Daniela. Universidad Diego Portales; ChileFil: Hurtado, Esteban. Universidad Diego Portales; ChileFil: Calvo Garbarino, Noelia Belén. Universidad Nacional de Córdoba. Facultad de Psicología; ArgentinaFil: Ibanez Barassi, Agustin Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Cuyo. Facultad de Educación Elemental y Especial; Argentina. Universidad Diego Portales; Chile. Centre of Excellence in Cognition and its Disorders; Australi

Rethinking the neural basis of prosody and non-literal language: Spared pragmatics and cognitive compensation in a bilingual with extensive right-hemisphere damage

Above and beyond the critical contributions of left perisylvian regions to language, the neural networks supporting pragmatic aspects of verbal communication in native and non-native languages (L1s and L2, respectively) have often been ascribed to the right hemisphere (RH). However, several reports have shown that left-hemisphere activity associated with pragmatic domains (e.g., prosody, indirect speech, figurative language) is comparable to or even greater than that observed in the RH, challenging the proposed putative role of the latter for relevant domains. Against this background, we report on an adult bilingual patient showing preservation of pragmatic verbal skills in both languages (L1: Spanish, L2: English) despite bilateral damage mainly focused on the RH. After two strokes, the patient sustained lesions in several regions previously implicated in pragmatic functions (vast portions of the right fronto-insulo-temporal cortices, the bilateral amygdalae and insular cortices, and the left putamen). Yet, comparison of linguistic and pragmatic skills with matched controls revealed spared performance on multiple relevant tasks in both her L1 and L2. Despite mild difficulties in some aspects of L2 prosody, she showed no deficits in comprehending metaphors and idioms, or understanding indirect speech acts in either language. Basic verbal skills were also preserved in both languages, including verbal auditory discrimination, repetition of words and pseudo-words, cognate processing, grammaticality judgments, equivalent recognition, and word and sentence translation. Taken together, the evidence shows that multiple functions of verbal communication can be widely spared despite extensive damage to the RH, and that claims for a putative relation between pragmatics and the RH may have been overemphasized in the monolingual and bilingual literature. We further discuss the case in light of previous reports of pragmatic and linguistic deficits following brain lesions and address its relation to cognitive compensation in bilingual patients.Fil: Calvo Garbarino, Noelia Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Abrevaya, Sofia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Martínez Cuitiño Carricaburo, María Macarena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Steeb, Brenda Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Zamora, Dolores Jazmín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Sedeño, Lucas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Ibanez Barassi, Agustin Mariano. Universidad Autónoma del Caribe; Colombia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Adolfo Ibañez; Chile. Australian Research Council; AustraliaFil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Cuyo; Argentin

Rethinking the neural basis of prosody and non-literal language: Spared pragmatics and cognitive compensation in a bilingual with extensive right-hemisphere damage

Above and beyond the critical contributions of left perisylvian regions to language, the neural networks supporting pragmatic aspects of verbal communication in native and non-native languages (L1s and L2, respectively) have often been ascribed to the right hemisphere (RH). However, several reports have shown that left-hemisphere activity associated with pragmatic domains (e.g., prosody, indirect speech, figurative language) is comparable to or even greater than that observed in the RH, challenging the proposed putative role of the latter for relevant domains. Against this background, we report on an adult bilingual patient showing preservation of pragmatic verbal skills in both languages (L1: Spanish, L2: English) despite bilateral damage mainly focused on the RH. After two strokes, the patient sustained lesions in several regions previously implicated in pragmatic functions (vast portions of the right fronto-insulo-temporal cortices, the bilateral amygdalae and insular cortices, and the left putamen). Yet, comparison of linguistic and pragmatic skills with matched controls revealed spared performance on multiple relevant tasks in both her L1 and L2. Despite mild difficulties in some aspects of L2 prosody, she showed no deficits in comprehending metaphors and idioms, or understanding indirect speech acts in either language. Basic verbal skills were also preserved in both languages, including verbal auditory discrimination, repetition of words and pseudo-words, cognate processing, grammaticality judgments, equivalent recognition, and word and sentence translation. Taken together, the evidence shows that multiple functions of verbal communication can be widely spared despite extensive damage to the RH, and that claims for a putative relation between pragmatics and the RH may have been overemphasized in the monolingual and bilingual literature. We further discuss the case in light of previous reports of pragmatic and linguistic deficits following brain lesions and address its relation to cognitive compensation in bilingual patients.Fil: Calvo Garbarino, Noelia Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Abrevaya, Sofia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Martínez Cuitiño Carricaburo, María Macarena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Steeb, Brenda Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Zamora, Dolores Jazmín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Sedeño, Lucas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Ibanez Barassi, Agustin Mariano. Universidad Autónoma del Caribe; Colombia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Adolfo Ibañez; Chile. Australian Research Council; AustraliaFil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Cuyo; Argentin

La renovación de la palabra en el bicentenario de la Argentina : los colores de la mirada lingüística

El libro reúne trabajos en los que se exponen resultados de investigaciones presentadas por investigadores de Argentina, Chile, Brasil, España, Italia y Alemania en el XII Congreso de la Sociedad Argentina de Lingüística (SAL), Bicentenario: la renovación de la palabra, realizado en Mendoza, Argentina, entre el 6 y el 9 de abril de 2010. Las temáticas abordadas en los 167 capítulos muestran las grandes líneas de investigación que se desarrollan fundamentalmente en nuestro país, pero también en los otros países mencionados arriba, y señalan además las áreas que recién se inician, con poca tradición en nuestro país y que deberían fomentarse. Los trabajos aquí publicados se enmarcan dentro de las siguientes disciplinas y/o campos de investigación: Fonología, Sintaxis, Semántica y Pragmática, Lingüística Cognitiva, Análisis del Discurso, Psicolingüística, Adquisición de la Lengua, Sociolingüística y Dialectología, Didáctica de la lengua, Lingüística Aplicada, Lingüística Computacional, Historia de la Lengua y la Lingüística, Lenguas Aborígenes, Filosofía del Lenguaje, Lexicología y Terminología

Grounding translation and interpreting in the brain: what has been, can be, and must be done

This paper offers an overview of neurocognitive research on translation and interpreting, an area whose history spans almost 100 years. First, we identify the main milestones in the development of this field, considering empirical breakthroughs (based on neuropsychological and neuroscientific evidence) as well as theoretical and institutional advances. Second, we review three areas of inquiry for which abundant evidence is already available, namely: (i) the circuits involved in backward and forward translation, (ii) the mechanisms engaged depending on variables of the translation unit, and (iii) the neurocognitive impact of expertise in simultaneous interpreting. Third, we discuss the field’s prospects for development, identifying key possibilities and methodological limitations. Finally, we enumerate the principal requirements for the consolidation of the neurocognitive approach (e.g. interdisciplinary training, greater collaboration between translation studies scholars and neuroscientists, increased funding, and presence in high-impact journals). In sum, we intend to show that knowledge about the cerebral basis of translation and interpreting has been growing over the decades and that conditions are appropriate for this promising space to assert itself as a full-fledged research arena.Fil: Muñoz, Edinson. Universidad de Santiago de Chile; ChileFil: Calvo Garbarino, Noelia Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Cuyo. Facultad de Educación Elemental y Especial; ArgentinaFil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Cuyo. Facultad de Educación Elemental y Especial; Argentin

A core avenue for transcultural research on dementia: on the cross-linguistic generalization of language-related effects in Alzheimer's disease and Parkinson's disease

Objective: Language is a key source of cross-cultural variability, which may have both subtle and major effects on neurocognition. However, this issue has been largely overlooked in two flourishing lines of research assessing the relationship between language-related neural systems and dementia. This paper assesses the limitations of the evidence on (i) the neuroprotective effects of bilingualism in Alzheimer´s disease and (ii) specific language deficits as markers of Parkinson´s disease. Design: First, we outline the rationale behind each line of research. Second, we review available evidence and discuss the potential impact of cross-linguistic factors. Third, we outline ideas to foster progress in both fields and, with it, in cross-cultural neuroscience at large. Results: On the one hand, studies on bilingualism suggest that sustained use of more than one language may protect against Alzheimer´s disease symptoms. On the other hand, insights from the embodied cognition framework point to syntactic and action-verb deficits as early (and even preclinical) markers of Parkinson´s disease. However, both fields share a key limitation that lies at the heart of cultural neuroscience: the issue of cross-linguistic generalizability. Conclusion: Relevant evidence for both research trends comes from only a handful of (mostly Indo-European) languages, which are far from capturing the full scope of structural and typological diversity of the linguistic landscape worldwide. This raises questions on the external validity of reported findings. Greater collaboration between linguistic typology and cognitive neuroscience seems crucial as a first step to assess the impact of transcultural differences on language-related effects across neurodegenerative diseases.Fil: Calvo Garbarino, Noelia Belén. Universidad Nacional de San Juan. Facultad de Filosofía, Humanidades y Artes; Argentina. Universidad Nacional de Córdoba. Facultad de Psicología; Argentina. Instituto de Neurología Cognitiva. Laboratorio de Psicología Experimental y Neurociencia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Ibáñez Barassi, Agustín Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Autónoma del Caribe; Colombia. Universidad Adolfo Ibañez; Chile. Australian Research Council; AustraliaFil: Muñoz, Edinson. Universidad de Santiago de Chile; ChileFil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Cuyo; Argentin

Bilingualism and cognitive reserve: A critical overview and a plea for methodological innovations

The decline of cognitive skills throughout healthy or pathological aging can be slowed down by experiences which foster cognitive reserve (CR). Recently, some studies on Alzheimer's disease have suggested that CR may be enhanced by life-long bilingualism. However, the evidence is inconsistent and largely based on retrospective approaches featuring several methodological weaknesses. Some studies demonstrated at least 4 years of delay in dementia symptoms, while others did not find such an effect. Moreover, various methodological aspects vary from study to study. The present paper addresses contradictory findings, identifies possible lurking variables, and outlines methodological alternatives thereof. First, we characterize possible confounding factors that may have influenced extant results. Our focus is on the criteria to establish bilingualism, differences in sample design, the instruments used to examine cognitive skills, and the role of variables known to modulate life-long cognition. Second, we propose that these limitations could be largely circumvented through experimental approaches. Proficiency in the non-native language can be successfully assessed by combining subjective and objective measures; confounding variables which have been distinctively associated with certain bilingual groups (e.g., alcoholism, sleep disorders) can be targeted through relevant instruments; and cognitive status might be better tapped via robust cognitive screenings and executive batteries. Moreover, future research should incorporate tasks yielding predictable patterns of contrastive performance between bilinguals and monolinguals. Crucially, these include instruments which reveal bilingual disadvantages in vocabulary, null effects in working memory, and advantages in inhibitory control and other executive functions. Finally, paradigms tapping proactive interference (which assess the disruptive effect of long-term memory on newly learned information) could also offer useful data, since this phenomenon seems to be better managed by bilinguals and it becomes conspicuous in early stages of dementia. Such considerations may shed light not just on the relationship between bilingualism and CR, but also on more general mechanisms of cognitive compensation.Fil: Calvo Garbarino, Noelia Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudio sobre Cultura y Sociedad. Centro de Investigaciones de la Facultad de Psicología - Grupo Vinculado CIPSI; Argentina. Universidad Nacional de San Juan; ArgentinaFil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Cuyo. Facultad de Educación Elemental y Especial; Argentina. Universidad Diego Portales; ChileFil: Manoiloff, Laura Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudio sobre Cultura y Sociedad. Centro de Investigaciones de la Facultad de Psicología - Grupo Vinculado CIPSI; ArgentinaFil: Ibáñez Barassi, Agustín Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Australian Research Council. Centre of Excellence in Cognition and its Disorders; Australia. Universidad Diego Portales; Chil