An evaluation of antimicrobial stewardship in community pharmacy

This study investigated several aspects of antimicrobial stewardship by gathering information from community pharmacists and members of the public. The aim was to identify how community pharmacists implement antimicrobial stewardship guidelines and influence patients on the use of antibiotics. This study required and received approval from the University of Huddersfield Ethics Committee. Information and opinions of community pharmacists in the Kirklees and Calderdale areas, and surrounding local areas, and of members of the public in Huddersfield town centre, were gathered using two different questionnaires. These focused on initiatives regarding antibiotic resistance, development of the competencies required for medicines optimisation and antimicrobial stewardship, patient education by pharmacists, monitoring of antibiotic prescribing and pharmacy access to records. The results obtained were then analysed. The study consisted of 50 participating pharmacists and 100 participating members of the public. It was identified that eight pharmacists had undertaken recent professional development regarding antimicrobial stewardship, 11 had made an Antibiotic Guardian pledge and eight monitored antibiotic prescribing. It was also discovered that, when handing out a prescription for antibiotics, five pharmacists (all of whom work in an independent pharmacy) always questioned the indication and seven always provided extra self-care information. Finally, 92 members of the public selected that they would be comfortable allowing their indication (the condition that the antibiotic is being used to treat) to be provided on prescriptions for antibiotics, and 83 selected that they would be comfortable with pharmacies having access to medical records. This study suggests that increased awareness is necessary of the resources that are available to pharmacists regarding antibiotic resistance initiatives and monitoring of antimicrobial prescribing. In addition, an improvement is required concerning patient education by community pharmacists. Finally, the public should be appropriately educated regarding patient confidentiality and the benefits of pharmacies having access to patient information

Depression in Collegiate Runners and Soccer Players: Relationships with Serum 25-Hydroxyvitamin D, Ferritin and Fractures

International Journal of Exercise Science 14(5): 1099-1111, 2021. The main purpose of this study was to evaluate relationships between depression versus serum 25-hydroxyvitamin D (vitamin D), serum ferritin (ferritin), and fractures across a competitive season. The authors conducted a prospective observational study (both pre- and post-season testing) on 51 collegiate soccer and cross-country athletes from a Midwest University. Our main outcome measure was depression, measured using the Center for Epidemiological Studies Depression Scale (CES-D). A CES-D score ≥ 16 represented the threshold value for clinical depression. Secondary outcome variables included vitamin D, ferritin, and fractures. Two athletes (3.9%; one female) pre-season while seven athletes (13.7%; five females) post-season demonstrated clinically relevant depression (CES-D score ≥ 16). Depression scores increased from pre- to post-season (6.0 to 8.9; p = 0.009; effect size = 0.53; n = 51). A medium effect noted for depressed athletes vs. non-depressed athletes (n = 7; post-season) to have lower pre-season serum vitamin D (38.4 vs. 50.2 ng/ml; p = 0.15; effect size = 0.68) with a small overall correlation effect (r = -0.08; p = 0.58). A medium correlation effect was noted between post-season ferritin vs. depression scores (r = -0.45; p = 0.01) in the female cohort only. Six athletes (11.8%) sustained fractures and had lower depression scores vs. non-injured athletes (4 vs. 10; p = 0.04; effect size = 1.08) post-season. Depression scores increased over a competitive season, especially in females. Small correlation effects were observed between depression and vitamin D. A medium correlation effect was noted between depression and low ferritin levels, in female athletes only. A large effect was noted between athletes sustaining fractures during the season and depression, post-season, with injured athletes being less depressed than non-injured athletes

Creating and Evaluating Multi-Document Sentence Extract

This paper discusses passage extraction approaches to multidocument summarization that use available information about the document set as a whole and the relationships between the documents to build on single document summarization methodology. Multi-document summarization differs from single in that the issues of compression, speed, redundancy and passage selection are critical in the formation of useful summaries, as well as the user's goals in creating the summary. Our approach addresses these issues by using domain-independent techniques based mainly on fast, statistical processing, a metric for reducing redundancy and maximizing diversity in the selected passages, and a modular framework to allow easy parameterization for different genres, corpora characteristics and user requirements. We examined how humans create multi-document summaries as well as the characteristics of such summaries and use these summaries to evaluate the performance of various multidocument summarization algorithms