Implementation of a Human Trafficking Educational Module for College Students: Pre/Post Design

This research study aimed to implement an educational module and to determine the effectiveness of that module on increasing the awareness of human trafficking and risk factors for incoming freshman students at a medium-size, Southern university from September 2021 through November 2021. Two hundred students consented and participated in the study by completing the pretest and posttest to indicate their knowledge of human trafficking before and after being presented an online educational module. The pre and posttest included 10 questions with 24 possible responses. An average of 12.34 correct responses were provided on the pretest and 19.13 were correct responses on the posttest. This data indicates a 58.6% improvement in awareness of human trafficking risk factors. A one-tailed pair-wise student’s t-test and a single factor ANOVA were used to compare pretest scores with posttest scores both resulting in a p value of \u3c 0.001. The results of the study support the original hypothesis that students will have greater knowledge and awareness of human trafficking, as evidenced by a positive change in pretest to posttest scores, after completing the educational module on human trafficking. Limitations were found in the study as some students did not complete both the pre and posttest. The researchers believe this could be addressed through a stepwise testing module where one has to complete the first step to proceed to the next

PD-1 gene polymorphism in children with subacute sclerosing panencephalitis

Subacute sclerosing panencephalitis (SSPE) is a progressive inflammatory and degenerative disorder of the central nervous system. Several factors influence the risk of chronic brain infection with the mutant measles virus. However, to date, no pathogenic mechanism that may predispose to SSPE has been determined. Studies have indicated that specific polymorphisms in certain host genes are probably involved in impairing the ability of host immune cells to eradicate the measles virus in SSPE patients. Programmed cell death protein 1 (PD-1), a member of the CD28 family, is a negative regulator of the immune system. The purpose of our study was to investigate whether PD-1 gene polymorphisms affect susceptibility to the development of SSPE in Turkish children. In total, 109 subjects (54 SSPE patients and 55 healthy controls) were genotyped for the PD-1.9 C/T (rs2227982) single-nucleotide polymorphism (SNP). The distributions of T alleles in the PD-1.9 polymorphism in SSPE patients and healthy controls were 2.8 and 10.9%, respectively. There was a statistically significant difference between the groups; the 95% confidence interval (CI) was 0.06 to 0.85 and the odds ratio (OR) was 0.23 (?2 test). Thus, we identified an association between SSPE and the PD-1 rs2227982 gene polymorphism; the frequency of T alleles was higher in controls than in SSPE patients. © Georg Thieme Verlag KG Stuttgart. New York