28 research outputs found

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    Bile acids and probiotics could help treating diabetes

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    On the exact analytical solution of some families of equilibrium critical thickness transcendental equations

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    The problem of finding an exact analytical closed-form solution of some families of transcendental equations, which describe the equilibrium critical thickness of misfit dislocation generation in epitaxial thin films, is studied in some detail by the Special Trans Functions Theory (STFT). A novel STFT mathematical approach with an analytical closed-form solution is presented. Structure of the STFT exact solutions, numerical results and graphical simulations confirm the validity of the basic principle of the STFT. The proposed STFT analytical approach shows qualitative improvement in theoretical sense (a novel gradient coefficient genesis), and, in accuracy when compared to the conventional analytical and numerical methods

    Review of batteries reliability in electric vehicle and E-mobility applications

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    Electric mobility (E-Mobility) has expedited transportation decarbonization worldwide. Lithium-ion batteries (LIBs) could help transition gasoline-powered cars to electric vehicles (EVs). However, several factors affect Li-ion battery technology in EVs’ short-term and long-term reliability. Li-ion batteries’ sensitivity and non-linearity may make traditional dependability models unreliable. This state-of-the-art article investigated power fade (PF) and capacity fade (CF) as leading reliability indicators that help analyze battery reliability under various ambient temperatures and discharge C-rates. Trends in LIBs applications for EVs and E-mobility are discussed. Furthermore, qualitative analysis and risk management were conducted to identify the reliable and unreliable zones of battery operation based on these indicators and the degradation circumstances implemented in recent publications. Besides, the influence of degrading circumstances on reliability indicators over the battery’s lifespan, such as a high C-rate at a low temperature throughout the battery's lifetime, has been presented in a comprehensive investigated case study in this work

    On the Exact Analytical Formulas of Leakage Current-Based Supercapacitor Model Operating in Industrial Applications

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    The resistance–capacitance (RC) model is one of the most applicable circuits for modeling the charging and discharging processes of supercapacitors (SCs). Although this circuit is usually used in the electric and thermal investigation of the performance of SCs, it does not include leakage currents. This paper presents exact analytical formulas of leakage-current-based supercapacitor models that can be used in industrial applications, i.e., constant-power-based applications. In the proposed model, current and voltage are represented as a solution of nonlinear equations that are solved using the standard Newton method. The proposed expressions’ accuracy is compared with the results obtained using traditional numerical integration methods with leakage current formulation and other methods, found in the literature, with no leakage current formulation. The results confirm that including leakage current represents a more accurate and realistic manner of modeling SCs. The results show that the derived expressions are precise, allowing the generation of results that closely match those obtained using traditional numerical-based methods. The derived expressions can be used to investigate SCs further and achieve more accurate and efficient regulation and control of SCs in different applications

    A novel exact analytical solution based on kloss equation towards accurate speed‐time characteristics modeling of induction machines during no‐load direct startups

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    The acceleration time of induction machines (IMs) is essential for proper protection‐relay settings of the machine to prevent voltage sags in local power areas. In this paper, mathematical modeling of IMs’ speed‐time characteristics during no‐load direct startup has been presented. Un-like the approaches presented in the literature, the proposed approach includes the bearing losses, in which two expressions of the speed‐time characteristics of IMs during no‐load direct startup are derived. The first expression was derived based on the Kloss equation used for representing the torque, and the second expression was derived based on the torque expression determined from the Thevenin equivalent circuit of the machine. The derived expressions’ accuracy was validated using laboratory measurement and computer simulation approaches. The results obtained show a good agreement between the measured and simulated speed‐time characteristics of two IMs. Fi-nally, the proposed formulations can provide a simple analytical base to enable accurate IM mod-eling

    Field Current Waveform-Based Method for Estimation of Synchronous Generator Parameters Using Adaptive Black Widow Optimization Algorithm

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    This article presents a novel method for identification of synchronous generator parameters that is based on sudden short-circuit test data and a novel metaheuristic algorithm, called the adaptive black widow optimization algorithm. Unlike traditional methods defined by IEEE and International Electrotechnical Commission (IEC) standards, which rely on the armature current oscillogram, the method proposed in this article uses the field current waveform during the short-circuit test. Moreover, the standard graphical method for extraction of the generator parameters is replaced by an effective metaheuristic algorithm. The proposed algorithm tends to minimize the normalized sum of squared errors (NSSE) between simulation and experimental results. The applicability and accuracy of the proposed optimization technique are verified using experimentally obtained results from a 100-MVA synchronous generator at the Bajina Basta hydropower plant

    Complex Machine-Learning Algorithms and Multivariable Logistic Regression on Par in the Prediction of Insufficient Clinical Response to Methotrexate in Rheumatoid Arthritis

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    The goals of this study were to examine whether machine-learning algorithms outper-form multivariable logistic regression in the prediction of insufficient response to methotrexate (MTX); secondly, to examine which features are essential for correct prediction; and finally, to in-vestigate whether the best performing model specifically identifies insufficient responders to MTX (combination) therapy. The prediction of insufficient response (3-month Disease Activity Score 28-Erythrocyte-sedimentation rate (DAS28-ESR) > 3.2) was assessed using logistic regression, least absolute shrinkage and selection operator (LASSO), random forest, and extreme gradient boosting (XGBoost). The baseline features of 355 rheumatoid arthritis (RA) patients from the “treatment in the Rotterdam Early Arthritis CoHort” (tREACH) and the U-Act-Early trial were combined for analyses. The model performances were compared using area under the curve (AUC) of receiver operating characteristic (ROC) curves, 95% confidence intervals (95% CI), and sensitivity and specificity. Fi-nally, the best performing model following feature selection was tested on 101 RA patients starting tocilizumab (TCZ)-monotherapy. Logistic regression (AUC = 0.77 95% CI: 0.68–0.86) performed as well as LASSO (AUC = 0.76, 95% CI: 0.67–0.85), random forest (AUC = 0.71, 95% CI: 0.61 = 0.81), and XGBoost (AUC = 0.70, 95% CI: 0.61–0.81), yet logistic regression reached the highest sensitivity (81%). The most important features were baseline DAS28 (components). For all algorithms, models with six features performed similarly to those with 16. When applied to the TCZ-monotherapy group, logistic regression’s sensitivity significantly dropped from 83% to 69% (p = 0.03). In the current dataset, logistic regression performed equally well compared to machine-learning algorithms in the prediction of insufficient response to MTX. Models could be reduced to six features, which are more conducive for clinical implementation. Interestingly, the prediction model was specific to MTX (combination) therapy response
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