Fault fictions : systematic biases in the conceptualization of fault zones

Mental models (i.e. a human’s internal representation of the real world) have an important role in the way a human understands and reasons about uncertainties, explores potential options, and makes decisions. However, they are susceptible to biases. Issues associated with mental models have not yet received much attention in geosciences, yet systematic biases can affect the scientific process of any geological investigation; from the inception of how the problem is viewed, through selection of appropriate hypotheses and data collection/processing methods, to the conceptualisation and communication of results. This article draws on findings from cognitive science and system dynamics, with knowledge and experiences of field geology, to consider the limitations and biases presented by mental models in geoscience, and their effect on predictions of the physical properties of faults in particular. We identify a number of biases specific to geological investigations and propose strategies for debiasing. Doing so will enhance how multiple data sources can be brought together, and minimise controllable geological uncertainty to develop more robust geological models. Critically, we argue that there is a need for standardised procedures that guard against biases, permitting data from multiple studies to be combined and communication of assumptions to be made. While we use faults to illustrate potential biases in mental models and the implications of these biases, our findings can be applied across the geoscience discipline

Multiparameter MR Imaging in the 6-OPRI

BACKGROUND AND PURPOSE: Inherited prion diseases represent over 15% of human prion cases and are a frequent cause of early onset dementia. The purpose of this study was to define the distribution of changes in cerebral volumetric and microstructural parenchymal tissues in a specific inherited human prion disease mutation combining VBM with VBA of cerebral MTR and MD. MATERIALS AND METHODS: VBM and VBA of cerebral MTR and MD were performed in 16 healthy control participants and 9 patients with the 6-OPRI mutation. An analysis of covariance consisting of diagnostic grouping with age and total intracranial volume as covariates was performed. RESULTS: On VBM, there was a significant reduction in gray matter volume in patients compared with control participants in the basal ganglia, perisylvian cortex, lingual gyrus, and precuneus. Significant MTR reduction and MD increases were more anatomically extensive than volume differences on VBM in the same cortical areas, but MTR and MD changes were not seen in the basal ganglia. CONCLUSIONS: Gray matter and WM changes were seen in brain areas associated with motor and cognitive functions known to be impaired in patients with the 6-OPRI mutation. There were some differences in the anatomic distribution of MTR-VBA and MD-VBA changes compared with VBM, likely to reflect regional variations in the type and degree of the respective pathophysiologic substrates. Combined analysis of complementary multiparameter MR imaging data furthers our understanding of prion disease pathophysiology

Interpreting mismatches between linguistic and genetic patterns among speakers of Tanimuka (Eastern Tukanoan) and Yukuna (Arawakan)

Horizon 2020(H2020)818854Descriptive and Comparative Linguistic

The social lives of isolates (and small language families): the case of the Northwest Amazon

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