15 research outputs found
Antibody to hepatitis C virus in blood donors found positive for other agents. II. Anti-HIV-1
Immunoregolatory T cell subsets in HIV and EBV infections: analysis with anti-2H4 and anti-4B4 antibodies
Multicentric electronic-based surveillance of treatment-limiting adverse events under HAART in the clinical setting. The italian MASTER clinical data base
Frequency of GBV-C viremia in Italian people with different risk factors for infection: implications for understanding GBV-C transmission.
Co-infezione HIV-HCV e dislipidemie in corso di terapia antiretrovirale ad elevata efficacia (HAART)
Transmission of HIV-associated tuberculosis to healthcare workers
OBJECTIVE:
A retrospective investigation was made to compare the occupational risk of tuberculosis in personnel assisting human immunodeficiency virus (HIV)-infected and uninfected subjects with active tuberculosis.
DESIGN:
We retrospectively reviewed 6 years of hospital activity in 3 units where HIV-infected patients with tuberculosis are hospitalized and in 2 units where non-HIV-infected tuberculosis patients are hospitalized. The risk of occupational tuberculosis in healthcare workers who assisted HIV-infected and non-HIV-infected patients with tuberculosis was investigated.
PARTICIPANTS:
The risk of occupational tuberculosis in healthcare workers was studied by considering the numbers of potential source cases (hospitalized patients with tuberculosis) in the two conditions investigated (HIV-positive and HIV-negative). Both potential source cases and cases of tuberculosis in healthcare workers had to be microbiologically proven in order to be considered.
RESULTS:
Seven cases of tuberculosis occurred in persons who cared for 85 HIV-infected subjects with tuberculosis, while only 2 cases occurred in staff members who took care of 1,079 HIV-negative tuberculosis patients over the same period (relative risk = 44.4; 95% confidence interval = 8.5-438).
CONCLUSIONS:
Tuberculosis seems no longer to be a neglectable risk in healthcare workers assisting patients with HIV infection. Further study is urgently needed to see whether such unexpectedly high dissemination of tuberculosis also is demonstrable in the community