6,253 research outputs found
Investigación en curso : Estudio exploratorio del estado de la producción intelectual Argentina desde el control bibliográfico nacional
La investigación se desarrolla en el marco del Programa de Reconocimiento Institucional de Investigaciones PRI 2015-2016, de la Facultad de Filosofía y Letras de la Universidad de Buenos Aires. Los miembros del equipo son: Irma Luz García, Mercedes Portugal, Nora Román, Claudia Crea y AlejandraVallespir. Es de carácter exploratoria y descriptiva y tiene como objetivo principal presentar la situación de la producción intelectual del país exclusivamente desde el control bibliográfico nacional, teniendo en cuenta las normativas legales, instrumentos y organismos involucrados en el registro, depósito y difusión de dicha producción. La problemática del control bibliográfico nacional y en particular, la correspondiente a la bibliografía nacional argentina, ha sido tratada por diversos autores sin ser ninguna de ellas investigaciones formales empíricas: Becu (1945), Ausa (1975), Galeotti (1985), Aguado de Costa, (1985), Sabor (1986), Pauliello de Chocholous (1986), Barber, Tripaldi y Pisano (1999). El último antecedente identificado sobre la problemática es una ponencia Romanos (2004). Estos trabajos presentan antecedentes, emprendimientos y recursos tendientes a mitigar la ausencia de control bibliográfico nacional, mencionando vacíos legales y normativos y proponiendo posibles soluciones. Los objetivos específicos que formulamos son: identificar los organismos públicos o privados que se encargan del registro y depósito; relevar y analizar los instrumentos de registro de los organismos considerando lo que la normativa vigente marca; analizar el funcionamiento de los mecanismos de depósito legal; relevar y analizar las características de los recursos/herramientas de difusión de los registros; identificar nuevas formas de acceso/depósito a la producción intelectual y explorar la relación con las tradicionales vigentes
Professional burnout among Catholic religious sisters in Italy : an empirical enquiry exploring the protective role of quality of community life
This study set out to examine three questions regarding the prevalence and correlates of burnout among a sample of 194 Catholic religious sisters in Italy who completed the Maslach Burnout Inventory alongside the Big Five Factor model of personality and the Index of Community Satisfaction. Regarding the prevalence of burnout, the data demonstrated that the mean scale scores of these sisters on emotional exhaustion, depersonalization, and personal accomplishment all came within the normal range proposed by the test manual. Regarding the personality correlates of burnout, the data demonstrated that the two key personality predictors of higher burnout scores among these sisters were high neuroticism scores and low agreeableness scores. High openness scores also predicted higher personal accomplishment, but were unrelated to differences in emotional exhaustion or in depersonalization. Regarding predictors of community life, after taking individual differences in age and personality into account, higher levels of community satisfaction were associated with lower levels of emotional exhaustion and lower levels of depersonalization, but unrelated to levels of personal accomplishment. This finding suggests that, a good quality of community life among religious sisters may enhance resilience against burnout, while a poor quality of community life among religious sisters may exacerbate burnout
Introduzione e commento a Carnelutti
Il lavoro è un commento ed una introduzione al parere redatto dal prof. Francesco Carnelutti, conservato in un carteggio del febbraio del 1930, reperibile presso l’archivio di Stato di Trieste negli atti generali della prefettura di Trieste ed inserito nella Busta 705/548. Il prof. Francesco Carnelutti si sofferma anche sulla situazione giuridica dei caolari esistenti sulle “motte” e li ritiene accessione della facoltà di pesca e precari, in base ad un ragionamento che si sofferma su due punti distinti. Preme notare come egli avendo negato l’esistenza dell’uso civico , quale logica conseguenza, non configuri nessun diritto di indennità spettante ai pescatori gradesi.. Si osserva come nel medesimo carteggio, si ritrovi, invece, una conclusione un po’ diversa alla diatriba riguardante il Fossalon
EZH2 Single Nucleotide Variants (SNVs): Diagnostic and Prognostic Role in 10 Solid Tumor Types
The enhancer of zeste homolog 2 (EZH2) gene encodes a histone methyltransferase that is a catalytic subunit of the Polycomb repressive complex 2 (PRC2) group of proteins that act to repress gene expression. The EZH2 locus is rarely mutated in solid tumors and there is no comprehensive study of EZH2 single nucleotide variants (SNVs) associated with cancer susceptibility, prognosis and response to therapy. Here, for the first time, we review the functional roles of EZH2 DNA variants and propose a putative etiological role in 10 various solid tumors including: esophageal, hepatocellular, oral, urothelial, colorectal, lung and gastric cancers. In particular, we found that the C allele of the EZH2 variant rs3757441 is associated with increased EZH2 RNA expression and poorer prognosis (advanced stage) in at least two malignancies such as colorectal and hepatocellular carcinoma. This suggests that the C allele may be a functional risk variant in multiple malignant tumors. We therefore propose that the rs3757441 single nucleotide variant (SNV) be genotyped and real-time PCR assays be performed in large cohort studies in order to confirm this preliminary finding that could be useful for clinical practice
Integrating practice based and neuroscientific perspectives on the impact of digital technology on contemporary narrative dramaturgy, investigated through live simulation exercises
University of Technology, Sydney. Faculty of Arts and Social Sciences.The collision of the dramatic and narrative arts with digital technology has seen the emergence of distinct narrative experiences incorporating new attributes such as interactivity and participant’s agency within the unfolding of the work. The disruption caused by these innovations and attributes has been hotly debated in many creative industry forums and further reinforced in theoretical discussions focussing on narrative and interactivity, a case in point being the ‘story versus game’ debates waged between the narratologists and the ludologists.
As a director and deviser of live performance, my own use of digital technology in productions throughout the 1990s generated concomitant dramaturgical dilemmas regarding the changing structure of narrative and the shifting role of the audience. From the outset of my investigations into these challenges it was clear there was a critical problem to be addressed. Temporality, and the ordering of experience and events in time, provides the foundation of storytelling and narrative dramaturgy. While conventional story structure is predicated on a reflective, re-telling of experience, games and many emerging forms appear to be contingent on a form of lived experience and enactment.
This doctorate examines particular aspects of narrative understanding as it is affected by the emergence of these new modes of dramaturgy and performance. Given that the new developments seemed to be challenging western dramatic conventions, in particular the key Aristotelian tenet of representation, I guided my research with this question: ‘How is this technological disruption renegotiating our traditional Aristotelian sense of time and presence?’
This thesis investigates the question from a neuroscientific perspective, integrating practice-based understandings and creative experimentation with neurobiological insights from Antonio Damasio, Francisco Varela and Benjamin Libet. It does so under the supposition that the shifts in narrative composition might in fact be reflective of how we process information. Further, it puts forward the proposal that we might enhance our understanding of contemporary narrative experiences by considering a model of dramaturgy that is informed by this understanding of the brain’s processing mechanisms.
In order to test this proposal I firstly set up a live simulation as an example of a technologized and interactive performed narrative, and then I distil four creative micro narratives from that simulation. I then analyse and discuss the micro narratives as forms of neurobiological sense making, potentially indicative of a compositional structure based on an alternate, neurobiological temporal dynamic.
The creative experiment and research findings (delivered in the exegesis) suggest the emergence of a new dramaturgical aesthetic and poetic of time; one that is predicated on a neurobiological dramaturgy distinguished by subjectivity, embodiment, enactment and above all, ‘presentness’
Attaccamento a Dio, attaccamento ai genitori e ai pari e atteggiamento religioso in un gruppo di adolescenti italiani
Numerosi contributi in letteratura descrivono il rapporto che un credente cattolico ha con Dio facendo riferimento ai concetti della teoria dell’attaccamento di Bowlby. In questa prospettiva le principali caratteristiche degli stili di attaccamento ai genitori e ai pari possono riproporsi nella relazione con Dio. Nel presente lavoro è stata indagata in un gruppo di 992 adolescenti cattolici la relazione tra gli stili di attaccamento ai genitori, ai pari e a Dio e il grado di influenza
di questi stili sull’atteggiamento religioso. Dai risultati emerge che le dimensioni insicure dell’attaccamento con i genitori e con i pari sono predittive di un attaccamento altrettanto insicuro e ansioso con Dio. Bassi livelli di attaccamento evitante o ansioso con Dio si riflettono in atteggiamenti positivi verso la religione e una maggiore partecipazione ai riti religiosi. I dati tendono a confermare l’ipotesi che il legame con Dio è influenzato dallo stile di attaccamento che il credente ha instaurato con i genitori e i pari. Tuttavia, dai risultati emerge che bassi livelli in alcune dimensioni dell’attaccamento (Comunicazione e Fiducia) tendono ad essere compensate nella relazione con Dio
Psychological temperament and the Catholic priesthood : an empirical enquiry among priests in Italy
This study draws on psychological type theory that has its origins in the work of Jung (1971) and psychological temperament theory as proposed by Keirsey and Bates (1978) to explore the psychological preferences and profile of Catholic priests serving in Italy. Data provided by 155 priests demonstrated an overwhelming preference for sensing and judging (SJ at 76 %), followed by intuition and feeling (NF at 12 %), intuition and thinking (NT at 8 %), and sensing and perceiving (SP at 5 %). In their study of styles of religious leadership, Oswald and Kroeger (1988) characterize the SJ preference as ‘the conserving serving pastor.’ The implications of these findings are discussed for leadership strengths and weaknesses in the Catholic Church
<b><i>Topoisomerase 1</i></b> Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patients
Objective: Topoisomerase 1 (topo-1) is an important target for the treatment of metastatic colorectal cancer (CRC). The aim of the present study was to evaluate the correlation between topo-1 single-nucleotide polymorphisms (SNPs) and clinical outcome in metastatic CRC (mCRC) patients.
Methods: With the use of specific software (PROMO 3.0), we performed an in silico analysis of topo-1 promoter SNPs; the rs6072249 and rs34282819 SNPs were included in the study. DNA was extracted from 105 mCRC patients treated with FOLFIRI ± bevacizumab in the first line. SNP genotyping was performed by real-time PCR. Genotypes were correlated with clinical parameters (objective response rate, progression-free survival, and overall survival).
Results: No single genotype was significantly associated with clinical variables. The G allelic variant of rs6072249 topo-1 SNP is responsible for GC factor and X-box-binding protein transcription factor binding. The same allelic variant showed a nonsignificant trend toward a shorter progression-free survival (GG, 7.5 months; other genotypes, 9.3 months; HR 1.823, 95% CI 0.8904-3.734; p = 0.1).
Conclusion: Further analyses are needed to confirm that the topo-1 SNP rs6072249 and transcription factor interaction could be a part of tools to predict clinical outcome in mCRC patients treated with irinotecan-based regimens
Openness to mystical experience and psychological type : a study among Italians
This study examines Ross’ thesis that intuitive types are more open than sensing types to mystical experience among a sample of 1,155 Italians who completed the Francis Psychological Type Scales alongside the Mystical Orientation Scale. The data supported Ross’ thesis. Intuitive types recorded a significantly higher mean score than sensing types on the index of mystical orientation. Ranking the sixteen complete types according to their mean mystical orientation scores located INFPs with the highest scores and ISTJs with the lowest scores
Experimental Comparison of the MIG and Friction Stir Welding Processes for AA 6005 Aluminium Alloy
In this study, the mechanical properties of welded joints of AA 6005 aluminum alloy
obtained with friction stir welding (FSW) and conventional metal inert gas welding (MIG) are
studied. FSW welds were carried out on a semi-automatic milling machine. The performance of
FSW and MIG welded joints were identified using tensile and bending impact tests, as far as the
environmental aspects are also included in the discussion. The joints obtained with FSW and MIG
processes were also investigated in their microstructure. The results indicate that, the microstructure
of the friction stir weld is different from that of MIG welded joint. The weld nugget consists of
small grains in FSW than those found in MIG weld. Taking into consideration the process
conditions and requirements, FSW and MIG processes were also compared with each other to
understand the advantages and disadvantages of the processes for welding applications of studied
Al alloy. Better tensile and bending strength were obtained with FSW welded joints
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