Helping families: childcare, early education and the work-life balance

Since Labour came to power in May 1997, there have been substantial increases in spending aimed at helping families with formal childcare, early education and the work-life balance. We look at the effects of these reforms and at the proposals of the parties in this area

The Compton-thick quasar at the heart of the high-redshift giant radio galaxy 6C 0905+39

Our XMM-Newton spectrum of the giant, high-redshift (z=1.88) radio galaxy 6C 0905+39 shows that it contains one of the most powerful, high-redshift, Compton-thick quasars known. Its spectrum is very hard above 2 keV. The steep XMM spectrum below that energy is shown to be due to extended emission from the radio bridge using Chandra data. The nucleus of 6C 0905+39 has a column density of 3.5 (+1.4,-0.4) X 10^24 cm^-2 and absorption-corrected X-ray luminosity of 1.7 (+0.9,-0.1) X 10^45 erg/s in the 2-10 keV band. A lower redshift active galaxy in the same field, SDSS J090808.36+394313.6, may also be Compton-thick.Comment: 5 pages, 5 figures, accepted to MNRA

The lone parent pilots after 12 to 24 months: an impact assessment of in-work credit, work search premium, extended schools childcare, quarterly work focused interviews and new deal plus for lone parents

From April 2004, a set of Government policies designed to help lone parents into work have been piloted in various combinations in a number of Jobcentre Plus districts in Great Britain. The five policies are: In Work Credit (IWC), Work Search Premium (WSP), Extended Schools Childcare (ESC) and Childcare Tasters, Quarterly Work Focused Interviews (QWFIs) for lone parents whose youngest child is aged 12 or over in Local Education Authorities (LEAs) in which an ESC pilot is operating (ESQWFI), and New Deal Plus for Lone Parents (ND+fLP), hereafter collectively referred to as 'the lone parent pilots' (LPPs or 'the pilots'). The pilots were rolled out in four Phases, the first three of which are analysed in this report. This report estimates the impact of the LPPs on lone parents who have received Income Support (IS) or Jobseeker's Allowance (JSA) for at least 12 months. It uses a difference-in-differences (DiD) estimator, and makes use of lone parents in districts not operating a pilot as a comparison group. The data covers the first 12 months (Phase 3 districts) to the first 24 months (Phase 1 districts) of the pilots' operation, and so should be seen as giving the early impacts. Impacts were estimated separately for the stock of lone parents who had been on benefit for at least 12 months when the pilots began, and the flow sample of lone parents whose claim of IS/JSA reached 12 months after the pilots began

Lagrangian acceleration statistics in turbulent flows

We show that the probability densities af accelerations of Lagrangian test particles in turbulent flows as measured by Bodenschatz et al. [Nature 409, 1017 (2001)] are in excellent agreement with the predictions of a stochastic model introduced in [C. Beck, PRL 87, 180601 (2001)] if the fluctuating friction parameter is assumed to be log-normally distributed. In a generalized statistical mechanics setting, this corresponds to a superstatistics of log-normal type. We analytically evaluate all hyperflatnes factors for this model and obtain a flatness prediction in good agreement with the experimental data. There is also good agreement with DNS data of Gotoh et al. We relate the model to a generalized Sawford model with fluctuating parameters, and discuss a possible universality of the small-scale statistics.Comment: 10 pages, 2 figure

Sympathetic nerve-derived ATP regulates renal medullary vasa recta diameter via pericyte cells: a role for regulating medullary blood flow?

Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins. We have previously shown that exogenous ATP causes constriction of vasa recta via renal pericytes, acting at a variety of membrane bound P2 receptors on descending vasa recta (DVR), and therefore may be able to regulate medullary blood flow (MBF). Regulation of MBF is essential for appropriate urine concentration and providing essential oxygen and nutrients to this region of high, and variable, metabolic demand. Various sources of endogenous ATP have been proposed, including from epithelial, endothelial, and red blood cells in response to stimuli such as mechanical stimulation, local acidosis, hypoxia, and exposure to various hormones. Extensive sympathetic innervation of the nephron has previously been shown, however the innervation reported has focused around the proximal and distal tubules, and ascending loop of Henle. We hypothesize that sympathetic nerves are an additional source of ATP acting at renal pericytes and therefore regulate MBF. Using a rat live kidney slice model in combination with video imaging and confocal microscopy techniques we firstly show sympathetic nerves in close proximity to vasa recta pericytes in both the outer and inner medulla. Secondly, we demonstrate pharmacological stimulation of sympathetic nerves in situ (by tyramine) evokes pericyte-mediated vasoconstriction of vasa recta capillaries; inhibited by the application of the P2 receptor antagonist suramin. Lastly, tyramine-evoked vasoconstriction of vasa recta by pericytes is significantly less than ATP-evoked vasoconstriction. Sympathetic innervation may provide an additional level of functional regulation in the renal medulla that is highly localized. It now needs to be determined under which physiological/pathophysiological circumstances that sympathetic innervation of renal pericytes is important

Detection of X-ray emission from the host clusters of 3CR quasars

We report the detection of extended X-ray emission around several powerful 3CR quasars with redshifts out to 0.73. The ROSAT HRI images of the quasars have been corrected for spacecraft wobble and compared with an empirical point-spread function. All the quasars examined show excess emission at radii of 15 arcsec and more; the evidence being strong for the more distant objects and weak only for the two nearest ones, which are known from other wavelengths not to lie in strongly clustered environments. The spatial profiles of the extended component is consistent with thermal emission from the intracluster medium of moderately rich host clusters to the quasars. The total luminosities of the clusters are in the range 4x10^44 - 3x10^45 erg/s, assuming a temperature of 4keV. The inner regions of the intracluster medium are, in all cases, dense enough to be part of a cooling flow.Comment: 21 pages including 4 figures and 4 tables. To be published in MNRA

System and method for moving a probe to follow movements of tissue

An apparatus is described for moving a probe that engages moving living tissue such as a heart or an artery that is penetrated by the probe, which moves the probe in synchronism with the tissue to maintain the probe at a constant location with respect to the tissue. The apparatus includes a servo positioner which moves a servo member to maintain a constant distance from a sensed object while applying very little force to the sensed object, and a follower having a stirrup at one end resting on a surface of the living tissue and another end carrying a sensed object adjacent to the servo member. A probe holder has one end mounted on the servo member and another end which holds the probe