Bioactive glass-derived trabecular coating: a smart solution for enhancing osteointegration of prosthetic elements

In this work, the use of foam-like glass-ceramic scaffolds as trabecular coatings on ceramic prosthetic devices to enhance implant osteointegration is proposed. The feasibility of this innovative device was explored in a simplified, flat geometry: glass-ceramic scaffolds, prepared by polymeric sponge replication and mimicking the trabecular architecture of cancellous bone, were joined to alumina square substrates by a dense glass coating (interlayer). The role played by different formulations of starting glasses was examined, with particular care to the effect on the mechanical properties and bioactivity of the final coating. Microindentations at the coating/substrate interface and tensile tests were performed to evaluate the bonding strength between the sample's components. In vitro bioactive behaviour was assessed by soaking in simulated body fluid and evaluating the apatite formation on the surface and inside the pores of the trabecular coating. The concepts disclosed in the present study can have a significant impact in the field of implantable devices, suggesting a valuable alternative to traditional, often invasive bone-prosthesis fixatio

Success and failure of experimental active glasses in periodontal disease repair

Four different ceramic materials, both inert and active, used in granule form for bone repair, were implanted in two sheep's jaws. After 3 months from the implant, the behaviour of the materials was studied by means of SEM and X-ray microprobe on thick sections of the embedded undecalcified jaws. The unexpected success of the inert materials and the failure of the used bioactive glass opens the problem of the calibration of the degradation parameters that must be evaluated both on the massive material and also on the granules or powders