4,578 research outputs found
Eyes Wide Shut: Expanding the view of portfolio management
This conceptual paper examines our existing world-view portfolio is defined the management of that portfolios from that of project and new product development portfolios to other portfolios that exist in an organisation, such as the asset portfolio, resource portfolio and ideas portfolio. Portfolios do not exist in isolation in an organisational context, but instead overlap and interact. This paper argues that there is a need to move another step higher, and examine the relationships between portfolios of projects and related activities across an organisation in order to optimise outcomes across the organisation. We propose the need for `enterprise portfolio management and suggest that this approach has the potential to improve organisational efficiency, and in the longer term could be a source of competitive advantage
Convergence of chiral effective field theory
We formulate the expansion for the mass of the nucleon as a function of pion
mass within chiral perturbation theory using a number of different ultra-violet
regularisation schemes; including dimensional regularisation and various
finite-ranged regulators. Leading and next-to-leading order non-analytic
contributions are included through the standard one-loop Feynman graphs. In
addition to the physical nucleon mass, the expansion is constrained by recent,
extremely accurate, lattice QCD data obtained with two flavors of dynamical
quarks. The extent to which different regulators can describe the chiral
expansion is examined, while varying the range of quark mass over which the
expansions are matched. Renormalised chiral expansion parameters are recovered
from each regularisation prescription and compared. We find that the
finite-range regulators produce consistent, model-independent results over a
wide range of quark mass sufficient to solve the chiral extrapolation problem
in lattice QCD.Comment: 13 pages, 13 figures; To appear in Progress in Particle and Nuclear
Physics; presented at Erice School on Quarks in Hadrons and Nuclei, September
200
Enhanced flight performance by genetic manipulation of wing shape in Drosophila
Insect wing shapes are remarkably diverse and the combination of shape and kinematics determines both aerial capabilities and power requirements. However, the contribution of any specific morphological feature to performance is not known. Using targeted RNA interference to modify wing shape far beyond the natural variation found within the population of a single species, we show a direct effect on flight performance that can be explained by physical modelling of the novel wing geometry. Our data show that altering the expression of a single gene can significantly enhance aerial agility and that the Drosophila wing shape is not, therefore, optimized for certain flight performance characteristics that are known to be important. Our technique points in a new direction for experiments on the evolution of performance specialities in animals
Three-dimensional arrangement of elastic fibers in the human corneal stroma
This is the final version of the article. Available from the publisher via the DOI in this record.The cornea is the main refracting lens in the eye. As part of the outer tunic it has to be resilient, a property conferred by the organisation of the constituent collagen. It also has to be sufficiently elastic to regain its exact shape when deformed, in order not to distort the retinal image. The basis of this elasticity is not fully understood. The purpose of this study was to characterise in three dimensions the arrangement and distribution of elastic fibers in the human corneal stroma, using serial block face scanning electron microscopy. We have demonstrated that there exists a complex network of elastic fibers that appear to originate in the sclera or limbus. These appear as elastic sheets in the limbus and peripheral cornea immediately above the trabecular meshwork which itself appears to extend above Descemet's membrane in the peripheral stroma. From these sheets, elastic fibers extend into the cornea; moving centrally they bifurcate and trifurcate into narrower fibers and are concentrated in the posterior stroma immediately above Descemet's membrane. We contend that elastic sheets will play an important role in the biomechanical deformation and recovery of the peripheral cornea. The network may also have practical implications for understanding the structural basis behind a number of corneal surgeries.We would like to thank Dr Anthony Hayes and Mr Derek Scarborough
for help with the histology presented in this study and Dr
Sally Hayes for useful discussions concerning data interpretation.
This work was funded by a Programme Grant (503626) from the
Medical Research Council (to KMM) and an MRC studentship (to
TW). We thank the CTC Eye Bank at Bristol, UK and the HDBR at
Newcastle, UK, for supply of human corneas. The authors have no
conflicts of interest to declare
Assessment of full field digital mammography (FFDM) detected microcalcification is not hindered by low spatial resolution
Good neighbours: distribution of black-tufted marmoset (Callithrix penicillata) in an urban environment
Context Primates are one of the most charismatic and widely studied vertebrate groups. However, the study of new world primates in green patches within urban areas has been neglected. Such primates have been viewed as a source of human–animal conflict; however, their ecological importance to urban ecosystems and their role in human well being is poorly understood. Aims To increase understanding of both ecological and socioeconomical factors affecting the distribution, density and group sizes of urban marmosets in a large Brazilian city (Belo Horizonte). Methods A map of vegetation cover and land use was produced and employed to investigate the distribution of marmosets. An online questionnaire was extensively publicised, which permitted the public to report the occurrence or not of marmosets near their residences. For sites with low salary levels and low internet availability, face-to-face interviews were conducted. Additionally, field surveys were conducted in 120 green areas identified by spatial analysis as potential areas of occurrence. The human population density, salary levels and green areas were posteriorly correlated with marmoset distribution. Key results Despite the urbanisation and high human population density, green fragments within the city still housed marmoset groups. However, the presence of green areas did not always indicate primate presence. Group presence was significantly related to the size of parks or green areas and negatively related to built-up areas, and human density. Salary levels were related to more forested streets and possibly tolerance. Marmosets were classified as urban utilisers. Conclusions The human–wildlife conflict with marmoset species was relatively low, owing to marmoset avoidance of built-up areas. The interaction of marmoset species and city dwellers was mainly limited to borders of forest fragments and inside city parks, and appeared to be human motivated. Implications This study showed the importance of public involvement in wildlife studies in urban environments; clarifying the interaction between city dwellers and wild species is essential to mitigate negative interactions
New evidence on Allyn Young's style and influence as a teacher
This paper publishes the hitherto unpublished correspondence between Allyn Abbott Young's biographer Charles Blitch and 17 of Young's former students or associates. Together with related biographical and archival material, the paper shows the way in which this adds to our knowledge of Young's considerable influence as a teacher upon some of the twentieth century's greatest economists. The correspondents are as follows: James W Angell, Colin Clark, Arthur H Cole, Lauchlin Currie, Melvin G de Chazeau, Eleanor Lansing Dulles, Howard S Ellis, Frank W Fetter, Earl J Hamilton, Seymour S Harris, Richard S Howey, Nicholas Kaldor, Melvin M Knight, Bertil Ohlin, Geoffrey Shepherd, Overton H Taylor, and Gilbert Walker
Impacts of removing badgers on localised counts of hedgehogs
This is the final version of the article. Available from Public Library of Science via the DOI in this record.Experimental evidence of the interactions among mammalian predators that eat or compete with one another is rare, due to the ethical and logistical challenges of managing wild populations in a controlled and replicated way. Here, we report on the opportunistic use of a replicated and controlled culling experiment (the Randomised Badger Culling Trial) to investigate the relationship between two sympatric predators: European badgers Meles meles and western European hedgehogs Erinaceus europaeus. In areas of preferred habitat (amenity grassland), counts of hedgehogs more than doubled over a 5-year period from the start of badger culling (from 0.9 ha-1 pre-cull to 2.4 ha-1 post-cull), whereas hedgehog counts did not change where there was no badger culling (0.3-0.3 hedgehogs ha-1). This trial provides experimental evidence for mesopredator release as an outcome of management of a top predator.The study was funded by the United Kingdom Government’s Department for Environment, Food and Rural Affairs (http://www.defra.gov.uk). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
Callout analysis in relation to wild birds in a tropical city: implications for urban species management
Urbanisation is changing landscapes at an unprecedented rate, which consequently changes species compositions. We investigate problems faced by urban birds in a neotropical city by analysing the responses made to callouts by the environmental police of Belo Horizonte, Minas Gerais, Brazil from 2002 to 2008. The environment police responded to two types of callouts: solicitation, where a person called to report an issue (n = 560); and reports of hurt or injured birds (n = 399). On average, three callouts per week were made relating to urban birds, with more than half concerning birds of prey. There were significantly more callouts in the wet season, coinciding with peak breeding times for most endemic Brazilian avifauna. We found no effect of caller gender, age or associated socioeconomic factors. Most callouts resulted in birds being forwarded on to Government-managed institute for processing wildlife (n = 584). Only a relatively small number of cases resulted in the birds being released into forested areas within the city (n = 152). Sick birds were sent to veterinary clinics (n = 136) and be released if successfully treated. We suggest how this information could be used to improve urban bird species management in neotropical cities. Our data evidences different guilds to have different relationships with people and birds of prey are less well-understood. The rise in callouts during breeding supports the need for better informed species management, and avoidance of a “one size fits all” approach
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