29 research outputs found
Feeling clumsy and curious. A collective reflection on experimenting with poetry as an unconventional method
In this paper, we offer a collective, multi-vocal reflection on using poetry for research purposes. These were reflections on an online sub-plenary session organized as a workshop, which was held at the European Group for Organization Studies conference in 2021. During this workshop, the first three authors presented a step-by-step method for doing poetic inquiry and invited participants to apply it to their own empirical data or research praxis. The method was created in response to the marginalization of affect and embodiment in mainstream research in organization studies. Poetic inquiry aims to formulate specific practices of âwriting differentlyâ that assist researchers in their attempts to analyze and articulate their findings in embodied and affec-tive ways. In this paper, we describe the method and bring together multi-vocal reflections from the participants and organizers of the workshop on the affects of poetic inquiry and the (ethical) questions that it poses.Publisher PDFPeer reviewe
Museum Audio Description: The Problem of Textual Fidelity
Museums present a myriad of source texts, which are often highly ambiguous. Yet Museum Audio Description (AD) is sited in an AD tradition which advocates objectivity. In screen AD, researchers have examined multiple aspects of the translation decisions facing the describer-translator, considering the ways in which AD is shaped by the demands of the source text, the impact of AD on the recipientâs experience and how these aspects may relate to objectivity. We examine the extent to which these decisions may apply to museum AD or differ in a museum setting. We argue that the notion of the âsource textâ for museums should be expanded beyond the visual elements of museumâs collections, encompassing the wider museum visiting experience. Drawing upon research from Museum Studies and Psychology, we explore the empirical evidence that characterises the experiences of mainstream sighted visitors and discuss the implications for museum AD. If it is to offer true access to the museum experience, then museum AD must consider not only the assimilation of visual information, but also the social, cognitive and emotional elements of visits. From this perspective, the emphasis is shifted from visual to verbal translation to the creative possibilities of re-creation in museum AD
CP-225,917 and CP-263,114 Synthesis Support Studies: Testing a Radical Cyclization Strategy for Installation of the Side-Chains
The selenocarbonate (18) has been prepared and shown to react with hexabutyldistannane hydride/allyltributylstannane to give, via a radical cyclization/allylation sequence, the lactone (21) embodying vicinal and trans-related functionality likely to be appropriate for elaboration to the side-chains associated with the title compounds (1) and (2) (phomoidrides A and B)
Dermatoses topographiques
Nous rapportons le contenu de la rĂ©union PEAUâse dermatologique des Cliniques universitaires Saint-Luc du 21 novembre 2016 consacrĂ©e aux dermatoses topographiques. Le Professeur D. Tennstedt, consultant dans le service de Dermatologie des Cliniques universitaires Saint-Luc, a prĂ©sentĂ© des cas de chĂ©ilites et dĂ©taillĂ© les dermatites de contact des lĂšvres. Les Docteurs C. Peeters et A. Coster, assistantes au sein du mĂȘme service, ont montrĂ© diffĂ©rentes pathologiques spĂ©cifiques des oreilles et du nez, respectivement.[Topographic dermatosis] We report the contents of the « PEAUâse dermatologique » meeting of the Cliniques Universitaires Saint-Luc of the 21th of November 2016 concerning the topographic dermatosis. Professor D. Tennstedt, consultant at the department of Dermatology at the Cliniques Universitaires Saint-Luc, presented cases of cheilitis and detailed the contact dermatitis of the lips. Doctors Caroline Peeters and Alison Coster, intern residents of the same department, displayed a set of specific pathologies concerning the ears and the nose, respectively
Dermatologie et hépatologie
Nous rapportons le contenu de la PEAUâse dermatologique du 24 avril 2017 organisĂ©e par le service de Dermatologie des Cliniques universitaires Saint-Luc et consacrĂ©e au foie et Ă la peau. Le Professeur Y. Horsmans, HĂ©patologue et Chef du DĂ©partement de MĂ©decine Interne aux Cliniques a exposĂ© la toxicitĂ© hĂ©patique des mĂ©dicaments prescrits en dermatologie. Le Professeur D. Tennstedt, Dermatologue du Service a ensuite rappelĂ© les signes cutanĂ©s associĂ©s Ă lâinfection par le virus de lâhĂ©patite C.We report the « PEAUse dermatologique » meeting of the Dermatology department of the Cliniques universitaires Saint-Luc which took place on April 24, 2017 and dedicated to liver and skin . Professor Y . Horsmans, Hepatologist and Head of the Department of Internal Medicine, presented the liver toxicity of drugs . Professor D . Tennstedt, Dermatologist of the Department, then described the cutaneous signs associated with hepatitis C virus infection
CP-225,917 and CP-263,114 Synthesis Support Studies: Testing a Radical Cyclization Strategy for Installation of the Side-Chains
Hypersensibilité aux médicaments
Cet article traite des rĂ©actions cutanĂ©es mĂ©dicamenteuses tant immĂ©diates que retardĂ©es. Celles-ci ont Ă©tĂ© prĂ©sentĂ©es lors de la « PEAU'se dermatologique » organisĂ©e par le service de Dermatologie des Cliniques universitaires Saint-Luc Ă Bruxelles en Janvier 2017 par le Professeur J-F. Nicolas et le Docteur S. Olivier. Le Professeur Nicolas a abordĂ© dans un premier temps les aspects cliniques mais aussi physiopathologiques de ces rĂ©actions cutanĂ©es aux mĂ©dicaments. Dans un second temps, le Docteur Olivier a rapportĂ© deux cas de pustulose exanthĂ©matique aiguĂ« gĂ©nĂ©ralisĂ©e sur terbinafine ainsi quâun cas de syndrome dâhypersensibilitĂ© mĂ©dicamenteuse (DRESS) sur traitement antituberculeux.This article deals with both immediate and delayed drug-induced cutaneous reactions . They were presented by Professor J-F . Nicolas and Doctor S . Olivier at the âPEAU'se dermatologiqueâ meeting, organized by the dermatology department of the Cliniques universitaires Saint-Luc, held in January 2017, in Brussels . Professor Nicolas first addressed the clinical as well as pathophysiological aspects of these cutaneous drug-induced reactions . Doctor Olivier then presented two clinical cases of acute generalized exanthematous pustulosis due to terbinafine, along with a case of drug hypersensitivity syndrome (DRESS) due to antituberculosis agents
A Total Synthesis of the Styryllactone (+)-Goniodiol from Naphthalene
The cytotoxic natural product (+)-goniodiol (1) has been prepared in twelve steps from the enantiomerically pure cis-dihydrocatechol (2), which is readily obtained by microbial oxidation of naphthalene. Elaboration of compound (2) involves an initial oxidative cleavage to dialdehyde (7) followed by reduction to give diol (12). Conversion of compound (12) into acetal (17) required, inter alia, selective oxidation of the benzylic alcohol moiety followed by a metal-catalyzed decarbonylation of the resulting aldehyde. Allylation of compound (17) with allyltributylstannane in the presence of lithium perchlorate gave a ca. 2.7:1 mixture of alcohols (18) and (19), each of which was converted into the corresponding acrylate under standard conditions. Subjection of these ester derivatives to a ring-closing metathesis (RCM) reaction with Grubbs' first-generation catalysts gave the anticipated lactones (22) and (23). Acid-catalyzed removal of the acetonide protecting group within compound (22) then afforded (+)-goniodiol (1), while analogous deprotection of congener (23) afforded 6-epi-(+)-goniodiol (24)
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome caused by firstâline antituberculosis drugs: Two case reports and a review of the literature
BACKGROUND: Patients suffering from drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome caused by first-line antituberculosis drugs often need to be retreated rapidly. Patch tests prior to the reintroduction of antituberculosis drugs are rarely performed.
OBJECTIVES: To highlight those drugs most often involved in DRESS caused by antituberculosis drugs, illustrate the potential value of patch tests to identify these culprit(s), and provide insights into how to rapidly retreat these patients.
METHODS: A detailed description of the work-up of two illustrative patients, together with a literature review of similar cases, is provided.
RESULTS: All first-line antituberculosis drugs may cause DRESS syndrome, but rifampicin and isoniazid are most frequently involved. Patch tests can be performed sooner than usually advised in the context of DRESS syndrome, and potentially with lower test concentrations, but false-negative results are possible. Sequential reintroduction of patch test-negative drugs is feasible, although the dose and order of drugs to be readministered, as well as the use of concomitant systemic corticosteroids, remain a matter of debate.
CONCLUSION: Patch tests in the context of DRESS syndrome caused by antituberculosis drugs, despite their shortcomings, may potentially guide rapid retreatment of these patients