3,7-Bis(dialkylamino)phenothiazin-5-ium derivatives: biomedical applications and biological activity

The light-induced reactions of 3,7-bis(dialkylamino)phenothiazin-5-ium compounds with biological substrates are briefly discussed. Their biomedical applications, in particular those related with biological staining, interaction with proteins and antiviral, antibacterial and antitumour activity are reviewed.info:eu-repo/semantics/publishedVersio

Efficacy and tolerability of airway stents

The function of airway stents is to keep the tubular structures open and stable. Their insertion is essentially indicated for intrinsic obstruction or extrinsic compression of the airway, fistulae or tracheobronchomalacia. The aim of this study was to determine the tolera bility and efficacy of airway stents in situations in which their insertion was vital. A retrospective study of airway stent insertion with rigid bronchoscopy (23 patients) was carried out over a two year period (2006-2007) at the Diagnostic and Therapeutic Techniques Unit. We assessed indication, efficacy, tolerability, complications and exact insertion based on chest CT imaging. In all situations Dumon flexible silicon stents (Tracheobronxane were used, with the need for complementary techniques such as laser therapy and mechanical dilation having been previously evaluated by flexible bronchoscopy. The authors conclude that stent insertion has no complications and good tolerability in the majority of advanced stage oncological situations with indication for palliative management

Avaliação de resistência à Sigatoka-amarela em genótipos de bananeira.

A bananeira é produzida em cerca de 150 países em todos os continentes. Em 2011 a produção brasileira de banana chegou a 7.023.396 toneladas/ano, com aumento em relação aos anos anteriores. Entre os problemas fitossanitários da bananeira, a Sigatoka-amarela, causada por Mycosphaerella musicola Leach, é um dos mais importantes, haja vista a sua dispersão no país com adaptabilidade a diferentes condições climáticas e causa perdas estimadas em 50% na produção, com possibilidade de atingir 100% em alguns microclimas

[Carotid atherosclerosis and white matter hypodensities: a controversial relationship]

INTRODUCTION: White matter hypodensities of presumed vascular origin, are recognized as an important cause of morbidity with established clinical and cognitive consequences. Nonetheless, many doubts remain on its physiopathology. Our goal is to clarify the potential role of carotid atherosclerosis and other vascular risk factors in the development of white matter hypodensities of presumed vascular origin. MATERIAL AND METHODS: We included patients that underwent CT brain scan and neurosonologic evaluation within a one-month period. Full assessment of vascular risks factors was performed. We seek to find independent associations between white matter hypodensities of presumed vascular origin, carotid intima-media thickness and vascular risk factors. RESULTS: 472 patients were included, mean age was 67.32 (SD: 14.75), 274 (58.1%) were male. The independent predictors of white matter hypodensities of presumed vascular origin were age (OR: 1.067, 95% IC: 1.049 - 1.086, p < 0.001) and hypertension (OR: 1.726, 95% IC: 1.097 - 2.715, p = 0.018). No association was found between IMT (OR: 2.613, 95% IC: 0.886 - 7.708, p = 0.082) or carotid artery stenosis (OR: 1.021, 95% IC: 0.785 - 1.328, p = 0.877) and white matter hypodensities of presumed vascular origin. DISCUSSION: Only age and hypertension proved to have an independent association with white matter hypodensities of presumed vascular origin. Carotid atherosclerosis, evaluated by IMT and the degree of carotid artery stenosis, showed no association with white matter hypodensities of presumed vascular origin. Since atherosclerosis is a systemic pathology, these results suggest that alternative mechanisms are responsible for the development of white matter hypodensities of presumed vascular origin. CONCLUSION: Age and hypertension seem to be the main factors in the development of white matter hypodensities of presumed vascular origin. No association was found between carotid atherosclerosis and white matter hypodensities of presumed vascular origin

Caracterização da estrutura de uma área de Floresta Ombrófila Mista sobre Latossolo Bruno em Gurapauva, Paraná, Brasil

Resumo

Where are the vertebras?

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Bentonite from Porto Santo Island, Madeira Archipelago: surface properties studied by inverse gas chromatography

The present paper shows the importance of Inverse Gas Chromatography (IGC) for the determination of the surface properties of bentonites. These properties are dispersive surface energy, acid-base properties, surface heterogeneity, sorption isotherms, BET surface areas and heat of sorption, using different probe molecules. IGC can contribute to the interpretation, prediction and optimization of the studied materials’ properties. The paper focuses on two distinctive bentonite samples from Porto Santo Island, Madeira archipelago. In view of their potential value, achieved through their incorporation in products for dermopharmacy and dermocosmetics, particle size and particle surface properties are of fundamental importance.info:eu-repo/semantics/publishedVersio

The Beta Generalized Exponential Distribution

We introduce the beta generalized exponential distribution that includes the beta exponential and generalized exponential distributions as special cases. We provide a comprehensive mathematical treatment of this distribution. We derive the moment generating function and the $r$th moment thus generalizing some results in the literature. Expressions for the density, moment generating function and $r$th moment of the order statistics also are obtained. We discuss estimation of the parameters by maximum likelihood and provide the information matrix. We observe in one application to real data set that this model is quite flexible and can be used quite effectively in analyzing positive data in place of the beta exponential and generalized exponential distributions