7,576 research outputs found
The thickness of a liquid layer on the free surface of ice as obtained from computer simulation
Molecular dynamic simulations were performed for ice Ih with a free surface
by using four water models, SPC/E, TIP4P, TIP4P/Ice and TIP4P/2005. The
behavior of the basal plane, the primary prismatic plane and of the secondary
prismatic plane when exposed to vacuum was analyzed. We observe the formation
of a thin liquid layer at the ice surface at temperatures below the melting
point for all models and the three planes considered. For a given plane it was
found that the thickness of a liquid layer was similar for different water
models, when the comparison is made at the same undercooling with respect to
the melting point of the model. The liquid layer thickness is found to increase
with temperature. For a fixed temperature it was found that the thickness of
the liquid layer decreases in the following order: the basal plane, the primary
prismatic plane, and the secondary prismatic plane. For the TIP4P/Ice model, a
model reproducing the experimental value of the melting temperature of ice, the
first clear indication of the formation of a liquid layer appears at about -100
Celsius for the basal plane, at about -80 Celsius for the primary prismatic
plane and at about -70 Celsius for the secondary prismatic plane.Comment: 41 pages and 13 figure
Photoluminescence Stokes shift and exciton fine structure in CdTe nanocrystals
The photoluminescence spectra of spherical CdTe nanocrystals with zincblende
structure are studied by size-selective spectroscopic techniques. We observe a
resonant Stokes shift of 15 meV when the excitation laser energy is tuned to
the red side of the absorption band at 2.236 eV. The experimental data are
analyzed within a symmetry-based tight-binding theory of the exciton spectrum,
which is first shown to account for the size dependence of the fundamental gap
reported previously in the literature. The theoretical Stokes shift presented
as a function of the gap shows a good agreement with the experimental data,
indicating that the measured Stokes shift indeed arises from the electron-hole
exchange interaction.Comment: 8 pages, 4 figures, LaTe
Magnetic permeability of ( Fe Co Ge ) 88 Zr 6 B 5 Cu 1 alloys: Thermal stability in a wide temperature range.
Temperature dependence, from room temperature up to 1000 K, of the initial permeability of
Fe83−xCoxGe5Zr6B5Cu1 x=5 and 20 alloys at different stages of devitrification is reported. As
nanocrystallization progresses, room temperature decreases but high temperature one increases,
leading to an improvement of its thermal stability extended from room temperature up to 915 K,
characterized by a temperature coefficient of permeability 0.1%/K 4000 and 0.04%/K
800 for 5 and 20 at. % Co containing alloys, respectively
RNA quantification using gold nanoprobes - application to cancer diagnostics
Molecular nanodiagnostics applied to cancer may provide rapid and sensitive detection of cancer related molecular alterations, which would enable early detection even when those alterations occur only in a small percentage of cells. The use of gold nanoparticles derivatized with thiol modified oligonucleotides (Au-nanoprobes) for the detection of specific nucleic acid targets has been gaining momentum as an alternative to more traditional methodologies. Here, we present an Au-nanoparticles based approach for the molecular recognition and quantification of the BCR-ABL fusion transcript (mRNA), which is responsible for chronic myeloid leukemia (CML), and to the best of our knowledge it is the first time quantification of a specific mRNA directly in cancer cells is reported. This inexpensive and very easy to perform Au-nanoprobe based method allows quantification of unamplified total human RNA and specific detection of the oncogene transcript. The sensitivity settled by the Au-nanoprobes allows differential gene expression from 10 ng/μl of total RNA and takes less than 30 min to complete after total RNA extraction, minimizing RNA degradation. Also, at later stages, accumulation of malignant mutations may lead to resistance to chemotherapy and consequently poor outcome. Such a method, allowing for fast and direct detection and quantification of the chimeric BCR-ABL mRNA, could speed up diagnostics and, if appropriate, revision of therapy. This assay may constitute a promising tool in early diagnosis of CML and could easily be extended to further target genes with proven involvement in cancer development
Detection of the onset of nanocrystallization by calorimetric and magnetic measurements
It is generally accepted that measurements of the magnetic properties are more sensitive than measurements of the enthalpy changes in the detection of the onset of crystallization of ferromagnetic phases emerging from a paramagnetic amorphous alloy. In this work, it is shown that the formation of a very fine nanocrystalline microstructure can make this assumption incorrect. Under some circumstances, the nanocrystallization onset temperature obtained from magnetic techniques is higher than the one obtained from enthalpy changes. The phenomenon is explained in terms of the superparamagnetic behavior of the uncoupled nanocrystals at the very early stages of nanocrystallizatio
A search for dark matter among Fermi-LAT unidentified sources with systematic features in Machine Learning
Around one third of the point-like sources in the Fermi-LAT catalogs remain
as unidentified sources (unIDs) today. Indeed, these unIDs lack a clear,
univocal association with a known astrophysical source. If dark matter (DM) is
composed of weakly interacting massive particles (WIMPs), there is the exciting
possibility that some of these unIDs may actually be DM sources, emitting gamma
rays from WIMPs annihilation. We propose a new approach to solve the standard,
Machine Learning (ML) binary classification problem of disentangling
prospective DM sources (simulated data) from astrophysical sources (observed
data) among the unIDs of the 4FGL Fermi-LAT catalogue. Concretely, we
artificially build two systematic features for the DM data which are originally
inherent to observed data: the detection significance and the uncertainty on
the spectral curvature. We do it by sampling from the observed population of
unIDs, assuming that the DM distributions would, if any, follow the latter. We
consider different ML models: Logistic Regression, Neural Network (NN), Naive
Bayes and Gaussian Process, out of which the best, in terms of classification
accuracy, is the NN, achieving around 93% performance. Applying the NN to the
unIDs sample, we find that the degeneracy between some astrophysical and DM
sources can be partially solved within this methodology. Nonetheless, we
conclude that there are no DM source candidates among the pool of 4FGL
Fermi-LAT unIDs.Comment: 13 pages, 14 figures, ready for submission to MNRA
Cherenkov Telescope Array sensitivity to branon dark matter models
This is the Accepted Manuscript version of an article accepted for publication in Journal of Cosmology and Astroparticle Physics. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at https://doi.org/10.1088/1475-7516/2020/10/041In the absence of a clear hint of dark matter (DM) signals in the GeV regime so far, heavy, O (TeV) DM candidates are gradually earning more and more attention within the community. Among others, extra-dimensional brane-world models may produce termal DM candidates with masses up to 100 TeV. These heavy DM candidates could be detected with the next generation of very-high-energy gamma-ray observatories such as the Cherenkov Telescope Array (CTA). In this work, we study the sensitivity of CTA to branon DM via the observation of representative astrophysical DM targets, namely dwarf spheroidal galaxies. In particular, we focus on Draco and Sculptor, two well-known dwarfs visible from the Northern and Southern Hemisphere, respectively. For each of these targets, we simulated 300 h of CTA observations and studied the sensitivity of both CTA-North and CTA-South to branon annihilations using the latest publicly available instrument response functions and most recent analysis tools. We computed annihilation cross section values needed to reach a 5σ detection as a function of the branon mass. Additionally, in the absence of a predicted DM signal, we obtained 2σ upper limits on the annihilation cross section. These limits lie 1.5 - 2 orders of magnitude above the thermal relic cross section value, depending on the considered branon mass. Yet, CTA will allow to exclude a significant portion of the brane tension-mass parameter space in the 0.1 - 60 TeV branon mass range, and up to tensions of ~ 10 TeV. More importantly, CTA will significantly enlarge the region already excluded by AMS and CMS, and will provide valuable complementary information to future SKA radio observations. We conclude that CTA will possess potential to constrain brane-world models and, more in general, TeV DM candidatesThe work of AAS, VG and MASC was supported by the Spanish Agencia Estatal de Investigación
through the grants PGC2018-095161-B-I00 and IFT Centro de Excelencia Severo
Ochoa SEV-2016-0597, the Atracción de Talento contract no. 2016-T1/TIC-1542 granted
by the Comunidad de Madrid in Spain, and the MultiDark Consolider Network FPA2017-
90566-REDC. DN acknowledges support from the former Spanish Ministry of Economy, Industry, and Competitiveness / European Regional Development Fund grant FPA2015-73913-JIN and the MultiDark Consolider Network FPA2017-90566-RED
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