Effect of interchain separation on the photoinduced absorption spectra of polycarbazolyldiacetylenes

The photoinduced absorption spectra of a novel polycarbazolyldiacetylene with long aliphatic chains on the carbazolyl side groups are measured and compared with those of the unsubstituted polyDCHD. The two polymers in the blue form exhibit very similar electronic absorption spectra and Raman frequencies. This fact indicates that the conjugation length of the polydiacetylene backbone is not too affected by the long substituents. In contrast, the near steady-state photoinduced absorption spectra show that different photogeneration mechanisms are involved in the two polymers. This result can be ascribed to the role played by the interchain distance in the dynamics of the relaxation processes in polydiacetylenes

Long-lived photoexcited states in polydiacetylenes with different molecular and supramolecular organization

With the aim of determining the importance of the molecular and supramolecular organization on the excited states of polydiacetylenes, we have studied the photoinduced absorption spectra of the red form of poly[1,6-bis(3,6-didodecyl-N-carbazolyl)-2,4-hexadiyne] (polyDCHD-S) and the results compared with those of the blue form of the same polymer. An interpretation of the data is given in terms of both the conjugation length and the interbackbone separation also in relation to the photoinduced absorption spectra of both blue and red forms of poly[1,6-bis(N-carbazolyl)-2,4-hexadiyne] (polyDCHD), which does not carry the alkyl substituents on the carbazolyl side groups. Information on the above properties is derived from the analysis of the absorption and Raman spectra of this class of polydiacetylenes

Safety of Biologic-DMARDs in Rheumatic Musculoskeletal Disorders: A Population-Based Study over the First Two Waves of COVID-19 Outbreak

This study aims to explore disease patterns of coronavirus disease (COVID-19) in patients with rheumatic musculoskeletal disorders (RMD) treated with immunosuppressive drugs in comparison with the general population. The observational study considered a cohort of RMD patients treated with biologic drugs or small molecules from September 2019 to November 2020 in the province of Udine, Italy. Data include the assessment of both pandemic waves until the start of the vaccination, between February 2020 and April 2020 (first), and between September 2020 and November 2020 (second). COVID-19 prevalence in 1051 patients was 3.5% without significant differences compared to the general population, and the course of infection was generally benign with 2.6% mortality. A small percentage of COVID-19 positive subjects were treated with low doses of steroids (8%). The most used treatments were represented by anti-TNF agents (65%) and anti-IL17/23 agents (16%). More than two-thirds of patients reported fever, while gastro-intestinal symptoms were recorded in 27% of patients and this clinical involvement was associated with longer swab positivity. The prevalence of COVID-19 in RMD patients has been confirmed as low in both waves. The benign course of COVID-19 in our patients may be linked to the very low number of chronic corticosteroids used and the possible protective effect of anti-TNF agents, which were the main class of biologics herein employed. Gastro-intestinal symptoms might be a predictor of viral persistence in immunosup-pressed patients. This finding could be useful to identify earlier COVID-19 carriers with uncommon symptoms, eventually eligible for antiviral drugs

Choosing between Homologous or Heterologous COVID-19 Vaccination Regimens: A Cross-Sectional Study among the General Population in Italy

A shortage of COVID-19 vaccines and reports of side-effects led several countries to recommend a heterologous regimen for second vaccine doses. This study aimed to describe the reasons behind individuals’ choices of a homologous or a heterologous second vaccination. This cross-sectional study enrolled individuals under 60 who had received a first dose of Vaxzevria and could choose between a homologous or heterologous regimen for their second dose. Quantitative (socio-demographic, clinical characteristics) and qualitative data were collected and analysed through a generalized linear model and thematic analysis, respectively. Of the 1437 individuals included in the analysis, the majority (76.1%) chose a heterologous second dose of the COVID-19 vaccination. More females chose a heterologous vaccination regimen (p = 0.003). Younger individuals also tended to choose heterologous vaccination (p < 0.001). The main motivation in favour of heterologous vaccination was to follow the Italian Ministry of Health recommendations (n = 118; 53.9%). This study showed that most individuals, mainly younger people and females, chose a heterologous dose of COVID-19 vaccination after their first viral vector vaccine. Heterologous vaccinations could be an effective public health measure to control the pandemic as they are a safe and efficient alternative to homologous regimens

Transmission curves and effective refraction indices of MKO near infrared consortium filters at cryogenic temperatures

We report transmission measurements at cryogenic temperatures for 4 broad-band filters of the Mauna Kea Observatories (MKO) near-infrared filter set and 5 narrow-band filters. The spectral scans were collected using the multi-mode IR instrument of the TNG telescope (NICS) in which these filters are permanently mounted and commonly used for astronomical observations. We determined the transmission curves at a temperature of 78K and found no significant red-leak up to 2.6 microns, the data are available in electronic form on the TNG web page. We also estimated the variation of the wavelength response with the incidence angle and found it compatible with an effective refractive index of about 2

Exploring Brown Dwarf Disks in rho Oph

This paper discusses evidence for and properties of disks associated to brown dwarfs in the star-forming region rho-Oph. We selected nine objects fr om the ISOCAM survey of Bontemps et al. (2001) that have detections in the two mid-infrared bands (6.7 and 14.3 um), relatively low extinction and low luminosity. We present low-resolution near-infrared spectra in the J, H and K bands, and determine for each source spectral type, extinction, effective temperature a nd luminosity by comparing the spectra to those of field dwarfs and to the most recent model stellar atmospheres. The results indicate that eight objects have spectral types M6-M7.5, effective temperature of 2600-2700 K, one has a later spectral type (M8.5) and lower temperature (about 2400 K). The derived extinctions range between Av~2 and 8 mag. The location of the objects on the HR diagram, in spite of the uncertainties of the evolutionary tracks for young objects of substellar mass, indicates that all the objects are very young and have masses below about 0.08 Msun. The coolest object in our sample has mass in the range 8-12 Mjup (0.008-0.012 Msun). In all cases, the mid-infrared excess is consistent with the predictions of mode ls of disks irradiated by the central object, showing that circumstellar disks are commonly associated to young brown dwarfs and plan etary-mass objects. Finally, we discuss possible variations of the disk geometry among different objects, as well as the possibility of using these data to discriminate between various f ormation scenarios.Comment: 15 pages, A&A in press, full resolution color figures for appendix A and B are available at http://www.arcetri.astro.it/~lt/preprints/preprints.htm

The TNG Near Infrared Camera Spectrometer

NICS (acronym for Near Infrared Camera Spectrometer) is the near-infrared cooled camera-spectrometer that has been developed by the Arcetri Infrared Group at the Arcetri Astrophysical Observatory, in collaboration with the CAISMI-CNR for the TNG (the Italian National Telescope Galileo at La Palma, Canary Islands, Spain). As NICS is in its scientific commissioning phase, we report its observing capabilities in the near-infrared bands at the TNG, along with the measured performance and the limiting magnitudes. We also describe some technical details of the project, such as cryogenics, mechanics, and the system which executes data acquisition and control, along with the related software.Comment: 7 pages, 5 figures, compiled with A&A macros. A&A in pres

A Young Very Low-Mass Object surrounded by warm dust

We present a complete low-resolution (R~100) near-infrared spectrum of the substellar object GY11, member of the rho-Ophiuchi young association. The object is remarkable because of its low estimated mass and age and because it is associated with a mid-infrared source, an indication of a surrounding dusty disk. Based on the comparison of our spectrum with similar spectra of field M-dwarfs and atmospheric models, we obtain revised estimates of the spectral type, effective temperature and luminosity of the central object. These parameters are used to place the object on a Hertzprung-Russell diagram and to compare with the prediction of pre-main sequence evolutionary models. Our analysis suggests that the central object has a very low mass, probably below the deuterium burning limit and in the range 8-12MJupiter, and a young age, less than 1Myr. The infrared excess is shown to be consistent with the emission of a flared, irradiated disk similar to those found in more massive brown dwarf and TTauri systems. This result suggests that substellar objects, even the so-called isolated planetary mass objects, found in young stellar associations are produced in a similar fashion as stars, by core contraction and gravitational collapse.Comment: Accepted by ApJ Letters, 13 pages 4 figure

Gravitational waves from coalescing binaries and Doppler experiments

Doppler tracking of interplanetary spacecraft provides the only method presently available for broad-band searches of low frequency gravitational waves. The instruments have a peak sensitivity around the reciprocal of the round-trip light-time T of the radio link connecting the Earth to the space-probe and therefore are particularly suitable to search for coalescing binaries containing massive black holes in galactic nuclei. A number of Doppler experiments -- the most recent involving the probes ULYSSES, GALILEO and MARS OBSERVER -- have been carried out so far; moreover, in 2002-2004 the CASSINI spacecraft will perform three 40 days data acquisition runs with expected sensitivity about twenty times better than that achieved so far. Central aims of this paper are: (i) to explore, as a function of the relevant instrumental and astrophysical parameters, the Doppler output produced by in-spiral signals -- sinusoids of increasing frequency and amplitude (the so-called chirp); (ii) to identify the most important parameter regions where to concentrate intense and dedicated data analysis; (iii) to analyze the all-sky and all-frequency sensitivity of the CASSINI's experiments, with particular emphasis on possible astrophysical targets, such as our Galactic Centre and the Virgo Cluster.Comment: 52 pages, LaTeX, 19 Postscript Figures, submitted to Phys. Rev.