39 research outputs found
Anomalous Couplings in Double Higgs Production
The process of gluon-initiated double Higgs production is sensitive to
non-linear interactions of the Higgs boson. In the context of the Standard
Model, studies of this process focused on the extraction of the Higgs trilinear
coupling. In a general parametrization of New Physics effects, however, an even
more interesting interaction that can be tested through this channel is the
(ttbar hh) coupling. This interaction vanishes in the Standard Model and is a
genuine signature of theories in which the Higgs boson emerges from a
strongly-interacting sector. In this paper we perform a model-independent
estimate of the LHC potential to detect anomalous Higgs couplings in
gluon-fusion double Higgs production. We find that while the sensitivity to the
trilinear is poor, the perspectives of measuring the new (ttbar hh) coupling
are rather promising.Comment: 22 pages, 9 figures. v2: plots of Figs.8 and 9 redone to include
experimental uncertainty on the Higgs couplings, references adde
Higgs boson production in photon-photon collision at ILC: a comparative study in different little Higgs models
We study the process \gamma\gamma->h->bb_bar at ILC as a probe of different
little Higgs models, including the simplest little Higgs model (SLH), the
littlest Higgs model (LH), and two types of littlest Higgs models with T-parity
(LHT-I, LHT-II). Compared with the Standard Model (SM) prediction, the
production rate is found to be sizably altered in these little Higgs models
and, more interestingly, different models give different predictions. We find
that the production rate can be possibly enhanced only in the LHT-II for some
part of the parameter space, while in all other cases the rate is suppressed.
The suppression can be 10% in the LH and as much as 60% in both the SLH and the
LHT-I/LHT-II. The severe suppression in the SLH happens for a large \tan\beta
and a small m_h, in which the new decay mode h->\eta\eta (\eta is a light
pseudo-scalar) is dominant; while for the LHT-I/LHT-II the large suppression
occurs when f and m_h are both small so that the new decay mode h->A_H A_H is
dominant. Therefore, the precision measurement of such a production process at
the ILC will allow for a test of these models and even distinguish between
different scenarios.Comment: Version in JHEP (h-g-g & h-gamma-gamma expressions added
Higgs Low-Energy Theorem (and its corrections) in Composite Models
The Higgs low-energy theorem gives a simple and elegant way to estimate the
couplings of the Higgs boson to massless gluons and photons induced by loops of
heavy particles. We extend this theorem to take into account possible nonlinear
Higgs interactions resulting from a strong dynamics at the origin of the
breaking of the electroweak symmetry. We show that, while it approximates with
an accuracy of order a few percents single Higgs production, it receives
corrections of order 50% for double Higgs production. A full one-loop
computation of the gg->hh cross section is explicitly performed in MCHM5, the
minimal composite Higgs model based on the SO(5)/SO(4) coset with the Standard
Model fermions embedded into the fundamental representation of SO(5). In
particular we take into account the contributions of all fermionic resonances,
which give sizeable (negative) corrections to the result obtained considering
only the Higgs nonlinearities. Constraints from electroweak precision and
flavor data on the top partners are analyzed in detail, as well as direct
searches at the LHC for these new fermions called to play a crucial role in the
electroweak symmetry breaking dynamics.Comment: 30 pages + appendices and references, 12 figures. v2: discussion of
flavor constraints improved; references added; electroweak fit updated,
results unchanged. Matches published versio
The s ---> d gamma decay in and beyond the Standard Model
The New Physics sensitivity of the s ---> d gamma transition and its
accessibility through hadronic processes are thoroughly investigated. Firstly,
the Standard Model predictions for the direct CP-violating observables in
radiative K decays are systematically improved. Besides, the magnetic
contribution to epsilon prime is estimated and found subleading, even in the
presence of New Physics, and a new strategy to resolve its electroweak versus
QCD penguin fraction is identified. Secondly, the signatures of a series of New
Physics scenarios, characterized as model-independently as possible in terms of
their underlying dynamics, are investigated by combining the information from
all the FCNC transitions in the s ---> d sector.Comment: 54 pages, 14 eps figure
In Vivo Gene Knockdown in Rat Dorsal Root Ganglia Mediated by Self-Complementary Adeno-Associated Virus Serotype 5 Following Intrathecal Delivery
We report here in adult rat viral vector mediate-gene knockdown in the primary sensory neurons and the associated cellular and behavior consequences. Self-complementary adeno-associated virus serotype 5 (AAV5) was constructed to express green fluorescent protein (GFP) and a small interfering RNA (siRNA) targeting mammalian target of rapamycin (mTOR). The AAV vectors were injected via an intrathecal catheter. We observed profound GFP expression in lumbar DRG neurons beginning at 2-week post-injection. Of those neurons, over 85% were large to medium-diameter and co-labeled with NF200, a marker for myelinated fibers. Western blotting of mTOR revealed an 80% reduction in the lumbar DRGs (L4–L6) of rats treated with the active siRNA vectors compared to the control siRNA vector. Gene knockdown became apparent as early as 7-day post-injection and lasted for at least 5 weeks. Importantly, mTOR knockdown occurred in large (NF200) and small-diameter neurons (nociceptors). The viral administration induced an increase of Iba1 immunoreactivity in the DRGs, which was likely attributed to the expression of GFP but not siRNA. Rats with mTOR knockdown in DRG neurons showed normal general behavior and unaltered responses to noxious stimuli. In conclusion, intrathecal AAV5 is a highly efficient vehicle to deliver siRNA and generate gene knockdown in DRG neurons. This will be valuable for both basic research and clinic intervention of diseases involving primary sensory neurons
Species Interactions during Diversification and Community Assembly in an Island Radiation of Shrews
Closely related, ecologically similar species often have adjacent distributions, suggesting competitive exclusion may contribute to the structure of some natural communities. In systems such as island archipelagos, where speciation is often tightly associated with dispersal over oceanic barriers, competitive exclusion may prevent population establishment following inter-island dispersal and subsequent cladogenesis.) species in the Philippines are the result of competitive exclusion preventing secondary invasion of occupied islands. We first compare ecological niche models between two widespread, allopatric species and find statistical support for their ecological similarity, implying that competition for habitat between these species is possible. We then examine dispersion patterns among sympatric species and find some signal for overdispersion of body size, but not for phylogenetic branch length. Finally, we simulate the process of inter-island colonization under a stochastic model of dispersal lacking ecological forces. Results are dependent on the geographic scope and colonization probability employed. However, some combinations suggest that the number of inter-island dispersal events necessary to populate the archipelago may be much higher than the minimum number of colonization events necessary to explain current estimates of species richness and phylogenetic relationships. If our model is appropriate, these results imply that alternative factors, such as competitive exclusion, may have influenced the process of inter-island colonization and subsequent cladogenesis.We interpret the combined results as providing tenuous evidence that similarity in body size may prevent co-occurrence in Philippine shrews and that competitive exclusion among ecologically similar species, rather than an inability to disperse among islands, may have limited diversification in this group, and, possibly other clades endemic to island archipelagos