28 research outputs found

    Expert consensus document:Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)

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    Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of biliary tract differentiation. CCA is the second most common primary liver tumour and the incidence is increasing worldwide. CCA has high mortality owing to its aggressiveness, late diagnosis and refractory nature. In May 2015, the "European Network for the Study of Cholangiocarcinoma" (ENS-CCA: www.enscca.org or www.cholangiocarcinoma.eu) was created to promote and boost international research collaboration on the study of CCA at basic, translational and clinical level. In this Consensus Statement, we aim to provide valuable information on classifications, pathological features, risk factors, cells of origin, genetic and epigenetic modifications and current therapies available for this cancer. Moreover, future directions on basic and clinical investigations and plans for the ENS-CCA are highlighted

    “Please do not leave any notes for the cleaning lady, as many do not speak English fluently”: policy, power and language brokering in a multilingual workplace.

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    This article investigates the covert language policy and micro-language planning practices of one female Brazilian-American entrepreneur, Magda, within her multilingual cleaning company. Because Magda is plurilingual (Spolsky in Language policy. Cambridge University Press, Cambridge, 2004), she is able to draw on her metalinguistic awareness and multicompetence in order to facilitate communication between her working-class migrant employees and her English-speaking clients as well as engage in what we call “inter-employee brokering”. Magda’s position as the company’s primary language broker enhances her authoritative power in both employer-employee and company owner-customer relations. The current study addresses the need to look into language practices and micro language planning within local contexts (Nekvapil and Nekula in Language planning in local contexts. Multilingual Matters, New York, pp 268–287, 2008) as well as blue-collar workplaces (Holmes in Continuum companion to discourse analysis. Continuum, London, pp 185–198, 2011; Lþnsmann and Kraft in The Routledge handbook of language in the workplace. Routledge, New York, forthcoming), which in one way reflect macro social structures, class differences and asymmetrical power relations concerning language use, but also emphasize a deviation from these macro-level patterns through the value placed on Portuguese as the lingua franca within the cleaning company
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