11 research outputs found

    Host-directed therapy targeting the Mycobacterium tuberculosis granuloma: a review

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    Metabolism: Pathogens love the poison

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    International audienceItaconate is a metabolite secreted by activated macrophages that inhibits pathogen growth. Some pathogens use itaconate degradation enzymes to promote their survival and infectivity, highlighting metabolic pathways to be considered in host-pathogen interactions

    Pathogens love the poison

    No full text
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