806 research outputs found

    A critical review of recent progress in mid-range wireless power transfer

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    Starting from Tesla’s principles of wireless power transfer a century ago, this critical review outlines recent magneto-inductive research activities on wireless power transfer with the transmission distance greater than the transmitter coil dimension. It summarizes the operating principles of a range of wireless power research into (i) the maximum power transfer and (ii) the maximum energy efficiency principles. The differences and the implications of these two approaches are explained in terms of their energy efficiency and transmission distance capabilities. The differences between the system energy efficiency and the transmission efficiency are also highlighted. The review covers the 2-coil systems, the 4-coil systems, the systems with relay resonators and the wireless domino-resonator systems. Related issues including human exposure issues and reduction of winding resistance are also addressed. The review suggests that the use of the maximum energy efficiency principle in the 2-coil systems is suitable for short-range rather than mid-range applications, the use of the maximum power transfer principle in the 4-coil systems is good for maximizing the transmission distance, but is under a restricted system energy efficiency (< 50%); the use of the maximum energy efficiency principle in relay or domino systems may offer a good compromise for good system energy efficiency and transmission distance on the condition that relay resonators can be placed between the power source and the load.published_or_final_versio

    Recent progress in mid-range wireless power transfer

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    This is a review paper describing recent progress of mid-range applications of wireless power transfer. Starting from Tesla's principles of wireless power transfer a century ago, it outlines magneto-inductive research activities in the last decade on wireless power transfer with the transmission distance in the order of or greater than the coil dimension. It covers the basic characteristics of 2-coil systems, 4-coil systems, systems with relay resonators and the wireless domino-resonator systems. © 2012 IEEE.published_or_final_versio

    Wireless Power Domino-Resonator Systems With Noncoaxial Axes and Circular Structures

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    Effects of magnetic coupling of nonadjacent resonators on wireless power domino-resonator systems

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    In this paper, the effects of the magnetic coupling of nonadjacent resonators on the optimal frequency of wireless power transfer are addressed. A power analysis has been carried out to identify the adjacent and nonadjacent power flow components. It is found that such cross-coupling effects of nonadjacent resonators would cause the maximum efficiency operation to slightly shift away from the resonance frequency of the resonators. Theoretical reasons for such phenomena are provided and experimentally confirmed with practical measurements in a wireless power transfer system comprising several magnetically coupled resonators arranged in a straight domino form. © 2011 IEEE.published_or_final_versio

    Glucose lowering effect of transgenic human insulin-like growth factor-I from rice: in vitro and in vivo studies

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    <p>Abstract</p> <p>Background</p> <p>Human insulin-like growth factor-I (hIGF-I) is a growth factor which is highly resemble to insulin. It is essential for cell proliferation and has been proposed for treatment of various endocrine-associated diseases including growth hormone insensitivity syndrome and diabetes mellitus. In the present study, an efficient plant expression system was developed to produce biologically active recombinant hIGF-I (rhIGF-I) in transgenic rice grains.</p> <p>Results</p> <p>The plant-codon-optimized hIGF-I was introduced into rice via <it>Agrobacterium</it>-mediated transformation. To enhance the stability and yield of rhIGF-I, the endoplasmic reticulum-retention signal and glutelin signal peptide were used to deliver rhIGF-I to endoplasmic reticulum for stable accumulation. We found that only glutelin signal peptide could lead to successful expression of hIGF-I and one gram of hIGF-I rice grain possessed the maximum activity level equivalent to 3.2 micro molar of commercial rhIGF-I. <it>In vitro </it>functional analysis showed that the rice-derived rhIGF-I was effective in inducing membrane ruffling and glucose uptake on rat skeletal muscle cells. Oral meal test with rice-containing rhIGF-I acutely reduced blood glucose levels in streptozotocin-induced and Zucker diabetic rats, whereas it had no effect in normal rats.</p> <p>Conclusion</p> <p>Our findings provided an alternative expression system to produce large quantities of biologically active rhIGF-I. The provision of large quantity of recombinant proteins will promote further research on the therapeutic potential of rhIGF-I.</p

    Understanding Water Level Changes in the Great Lakes by an ICA-Based Merging of Multi-Mission Altimetry Measurements

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    Accurately monitoring spatio-temporal changes in lake water levels is important for studying the impacts of climate change on freshwater resources, and for predicting natural hazards. In this study, we applied multi-mission radar satellite altimetry data from the Laurentian Great Lakes, North America to optimally reconstruct multi-decadal lake-wide spatio-temporal changes of water level. We used the results to study physical processes such as teleconnections of El Niño and southern oscillation (ENSO) episodes over approximately the past three-and-a-half decades (1985–2018). First, we assessed three reconstruction methods, namely the standard empirical orthogonal function (EOF), complex EOF (CEOF), and complex independent component analysis (CICA), to model the lake-wide changes of water level. The performance of these techniques was evaluated using in-situ gauge data, after correcting the Glacial Isostatic Adjustment (GIA) process using a contemporary GIA forward model. While altimeter-measured water level was much less affected by GIA, the averaged gauge-measured water level was found to have increased up to 14 cm over the three decades. Our results indicate that the CICA-reconstructed 35-year lake level was more accurate than the other two techniques. The correlation coefficients between the CICA reconstruction and the in situ water-level data were 0.96, 0.99, 0.97, 0.97, and 0.95, for Lake Superior, Lake Michigan, Lake Huron, Lake Erie, and Lake Ontario, respectively; ~7% higher than the original altimetry data. The root mean squares of errors (RMSE) were 6.07 cm, 4.89 cm, 9.27 cm, 7.71 cm, and 9.88 cm, respectively, for each of the lakes, and ~44% less than differencing with the original altimetry data. Furthermore, the CICA results indicated that the water-level changes in the Great Lakes were significantly correlated with ENSO, with correlation coefficients of 0.5–0.8. The lake levels were ~25 cm higher (~30 cm lower) than normal during EI Niño (La Niña) events

    Classification of gluteal muscle contracture in children and outcome of different treatments

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    <p>Abstract</p> <p>Background</p> <p>Gluteal muscle contracture (GMC) is a clinical syndrome due to multiple etiologies in which hip movements may be severely limited. The aim of this study was to propose a detailed classification of GMC and evaluate the statistical association between outcomes of different management and patient conditions.</p> <p>Methods</p> <p>One hundred fifty-eight patients, who were treated between January 1995 and December 2004, were reviewed at a mean duration of follow-up of 4.8 years. Statistical analyses were performed using X<sup>2 </sup>and Fisher's exact tests.</p> <p>Results</p> <p>Non-operative management (NOM), as a primary treatment, was effective in 19 of 49 patients (38.8%), while operative management was effective in all 129 patients, with an excellence rating of 83.7% (108/129). The outcome of NOM in level I patients was significantly higher than in level II and III patients (<it>P </it>< 0.05). The results of NOM and operative management in the child group were better than the adolescent group (<it>P </it>< 0.05). Complications in level III were more than in level II.</p> <p>Conclusion</p> <p>NOM was more effective in level I patients than in level II and III patients. Operative management was effective in patients at all levels, with no statistical differences between levels or types. We recommend NOM as primary treatment for level I patients and operative management for level II and III patients. Either NOM or operative management should be carried out as early as possible.</p

    The value of diffusion-weighted imaging in assessing the ADC changes of tissues adjacent to breast carcinoma

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    <p>Abstract</p> <p>Background</p> <p>To define a threshold value of apparent diffusion coefficient (ADC) with which malignant breast lesions can be distinguished from benign lesions, and to evaluate the ADC change of peri-tumor tissue in breast carcinoma by echo planar-diffusion weighted imaging (EPI-DWI).</p> <p>Methods</p> <p>57 breast lesions were scanned by routine MRI and EPI-DWI. The ADC values were compared between malignant and benign lesions. The sensitivity and specificity of EPI-DWI and the threshold ADC value were evaluated by Receiver Operating Characteristic curve (ROC). The ADC values of malignant lesion and layered peri-tumor tissues (from innermost layer 1 to outermost layer 4 with 5 mm every layer) in different directions were compared and the ADC values among different layers were compared.</p> <p>Results</p> <p>The ADC value of 35 malignant lesions was statistically lower than that of 22 benign lesions (P < 0.05). In ROC curve, the threshold value was 1.24 +/- 0.25*10E-3 mm<sup>2</sup>/s (b = 500) or 1.20 +/- 0.25*10E-3 mm<sup>2</sup>/s (b = 1000). The ADC value of malignant lesions was statistically lower than that of peri-tumor tissues in different directions (P < 0.05). For peri-tumor tissues, the ADC values increased gradually from layer 1 to layer 4 and there was a significant difference between the ADC values of layer 1 and layer 2 (P < 0.05); while from layer 2 outwards, there was no statistical difference among different layers.</p> <p>Conclusion</p> <p>ADC value was a sensitive and specific parameter that could help to differentiate benign and malignant breast lesions. ADC changes in tissues adjacent to breast carcinoma could be detected by EPI-DWI, which made EPI-DWI a promising method for helping to determine surgical scope of breast carcinoma.</p
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