A validated normative model for human uterine volume from birth to age 40 years

Transabdominal pelvic ultrasound and/or pelvic Magnetic Resonance Imaging are safe, accurate and non - invasive means of determining the size and configuration of the internal female genitalia. The assessment of uterine size and volume is helpful in the assessment of many conditions including disorders of sex development, precocious or delayed puberty, infertility and menstrual disorders. Using our own data from the assessment of MRI scans in healthy young females and data extracted from four studies that assessed uterine volume using transabdominal ultrasound in healthy females we have derived and validated a normative model of uterine volume from birth to age 40 years. This shows that uterine volume increases across childhood, with a faster increase in adolescence reflecting the influence of puberty, followed by a slow but progressive rise during adult life. The model suggests that around 84% of the variation in uterine volumes in the healthy population up to age 40 is due to age alone . The derivation of a validated normative model for uterine volume from birth to age 40 years has important clinical applications by providing age-related reference values for uterine volume.Publisher PDFPeer reviewe

Juvenile megamouth shark, Megachasma pelagios, caught off the Pacific coast of Mexico, and its significance to chondrichthyan diversity in Mexico

On 16 November 2006, a female juvenile megamouth shark, Megachasma pelagios, was caught off the coast of Mexico in the Pacific Ocean, near Sebastián Vizcaíno Bay. This specimen, that has informally been referred to as “Megamouth No. 38”, measured 2265 mm in total length. It represents the third smallest female recorded for this taxon and the first report of M. pelagios off the Pacific coast of Mexico. The specimen is formally described here with basic anatomical data, and some aspects of this megamouth shark are compared with those of previously reported M. pelagios specimens. The occurrence near Sebastián Vizcaíno Bay is significant because it further emphasizes the high elasmobranch diversity in the area that should be regarded as a key region for shark conservation.