108 research outputs found
Density is in the eye of the beholder: visual versus semi-automated assessment of breast density on standard mammograms
Quantification of masking risk in screening mammography with volumetric breast density maps
The Short-Term Effect of Weight Loss Surgery on Volumetric Breast Density and Fibroglandular Volume
Purpose:
Obesity and breast density are both associated with an increased risk of breast cancer and are potentially modifiable. Weight loss surgery (WLS) causes a significant reduction in the amount of body fat and a decrease in breast cancer risk. The effect of WLS on breast density and its components has not been documented. Here, we analyze the impact of WLS on volumetric breast density (VBD) and on each of its components (fibroglandular volume and breast volume) by using three-dimensional methods.
Materials and Methods:
Fibroglandular volume, breast volume, and their ratio, the VBD, were calculated from mammograms before and after WLS by using VolparaĂąâÂą automated software.
Results:
For the 80 women included, average body mass index decreased from 46.0 ñ 7.22 to 33.7 ñ 7.06 kg/m2. Mammograms were performed on average 11.6 ñ 9.4 months before and 10.1 ñ 7 months after WLS. There was a significant reduction in average breast volume (39.4 % decrease) and average fibroglandular volume (15.5 % decrease), and thus, the average VBD increased from 5.15 to 7.87 % (p < 1 Ăâ 10ĂąËâ9) after WLS. When stratified by menopausal status and diabetic status, VBD increased significantly in all groups but only perimenopausal and postmenopausal women and non-diabetics experienced a significant reduction in fibroglandular volume.
Conclusions:
Breast volume and fibroglandular volume decreased, and VBD increased following WLS, with the most significant change observed in postmenopausal women and non-diabetics. Further studies are warranted to determine how physical and biological alterations in breast density components after WLS may impact breast cancer risk.ECU Open Access Publishing Support Fun
Preliminary evaluation of the publicly available Laboratory for Breast Radiodensity Assessment (LIBRA) software tool: comparison of fully automated area and volumetric density measures in a caseâcontrol study with digital mammography
Computer-aided detection in full-field digital mammography in a clinical population: performance of radiologist and technologists
Invasive ductolobular carcinoma of the breast: spectrum of mammographic, ultrasound and magnetic resonance imaging findings correlated with proportion of the lobular component
Not all false positive diagnoses are equal: On the prognostic implications of false-positive diagnoses made in breast MRI versus in mammography / digital tomosynthesis screening
Diminishing benefits of urban living for children and adolescentsâ growth and development
AbstractOptimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1â6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71âmillion participants, to report the height and body-mass index (BMI) of children and adolescents aged 5â19âyears on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1âkgâmâ2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified.</jats:p
Multidisciplinary Collaboration for the Development of Innovative Solutions in Health Care: The Case of the IMED Project
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