62 research outputs found

    Analysis of the Plant bos1 Mutant Highlights Necrosis as an Efficient Defence Mechanism during D. dadantii/Arabidospis thaliana Interaction

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    Dickeya dadantii is a broad host range phytopathogenic bacterium provoking soft rot disease on many plants including Arabidopsis. We showed that, after D. dadantii infection, the expression of the Arabidopsis BOS1 gene was specifically induced by the production of the bacterial PelB/C pectinases able to degrade pectin. This prompted us to analyze the interaction between the bos1 mutant and D. dadantii. The phenotype of the infected bos1 mutant is complex. Indeed, maceration symptoms occurred more rapidly in the bos1 mutant than in the wild type parent but at a later stage of infection, a necrosis developed around the inoculation site that provoked a halt in the progression of the maceration. This necrosis became systemic and spread throughout the whole plant, a phenotype reminiscent of that observed in some lesion mimic mutants. In accordance with the progression of maceration symptoms, bacterial population began to grow more rapidly in the bos1 mutant than in the wild type plant but, when necrosis appeared in the bos1 mutant, a reduction in bacterial population was observed. From the plant side, this complex interaction between D. dadantii and its host includes an early plant defence response that comprises reactive oxygen species (ROS) production accompanied by the reinforcement of the plant cell wall by protein cross-linking. At later timepoints, another plant defence is raised by the death of the plant cells surrounding the inoculation site. This plant cell death appears to constitute an efficient defence mechanism induced by D. dadantii during Arabidopsis infection

    Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry

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    Diseño de un modelo de referenciación a personas en emergencia social víctimas del conflicto armado residentes en Bogotá

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    Tesis de GradoEl propósito de la investigación fue diseñar la estructura conceptual de un modelo de referenciación para víctimas del conflicto armado atendidas en el servicio Enlace Social de la Secretaria Distrital de Integración Social residentes Bogotá. Así como, realizar la caracterización de 361 registros de la ficha del sistema de registro de beneficiarios SIRBE aplicada a VCA participantes en el servicio ES de la SDIS desde el año 2013 hasta Septiembre del 2017 y caracterización 18 instituciones y 29 programas o servicios dirigidos a VCA con el fin de identificar la oferta de servicios sociales disponibles para este grupo poblacional.1. Resumen 2. Antecedentes conceptuales y empíricos 3. Justificación 4. Objetivos 5. Método 6. Resultados 7. Discusión y conclusiones 8. Referencias 9. ApéndicesMaestríaMagister en Psicologí
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