Incidenza di adenocarcinoma tra i pazienti con Esofago di Barrett

Revisione della Letteratur

Barrett's esophagus

Barrett\u2019s esophagus is a precancerous condition associated with an increased risk of esophageal adenocarcinoma. A diagnosis of Barrett\u2019s esophagus may cause psychological stress with a negative impact on patients\u2019 quality of life. In line with the increasing prevalence of gastro-esophageal reflux disease, the incidence of Barrett\u2019s esophagus has raised dramatically over the last decades, particularly in Europe. Several international guidelines and experts consensus on the diagnosis and management of Barrett\u2019s esophagus have been published over the last years. There are still areas of controversy surrounding the diagnosis of Barrett\u2019s esophagus, in particular concerning the histological type of metaplastic epithelium, and treatment modalities, including medical therapy for chemoprevention and endoscopic techniques. The purpose of this review is to examine the current guidelines and recommendations, and report recent evidence from systematic reviews and clinical trials on epidemiology, diagnosis, surveillance and treatment of Barrett\u2019s esophagus