Biochemical mechanisms of the effect of environmental factors (diet, fluorine, alcohol and tobacco) on oral health

Nowadays, oral diseases are prevalent chronic diseases present in worldwide population. Dental caries results from a complex interaction between acid-producing bacteria, fermentable carbohydrates and host factors, including teeth and saliva. Risk factors for caries development include physical, biological, environmental, behavioral factors such as high numbers of cariogenic bacteria, inadequate salivary flow, poor oral hygiene and poor eating habits. Moreover, due to its efficacy in caries prevention, fluorine has been added to toothpaste, supplements and water. However, despite of its beneficial effect, excessive intake can lead to acute or chronic toxic effects, that depend on ingestion period and ingested amount, age, cardiovascular or renal problems and genetic changes. The most common adverse effects of excessive fluorine intake are dental and skeletal fluorosis. Another oral health problem is oral cancer, one of the most common cancers in the world and a highly relevant problem of global public health, mainly affecting lips and oral cavity. It is a preventable disease, where tobacco and alcohol, considered major risk factors, are present with a synergic effect in 90% of cases. Alcohol can act as a risk factor both locally and systemically, being causally associated with oropharyngeal and larynx cancer, esophageal cancer, among others.info:eu-repo/semantics/publishedVersio

Dirac quasinormal modes of the Reissner-Nordstr\"om de Sitter black hole

The quasinormal modes of the Reissner-Nordstr\"om de Sitter black hole for the massless Dirac fields are studied using the P\"oshl-Teller potential approximation. We find that the magnitude of the imaginary part of the quasinormal frequencies decreases as the cosmological constant or the orbital angular momentum increases, but it increases as the charge or the overtone number increases. An interesting feature is that the imaginary part is almost linearly related to the real part as the cosmological constant changes for fixed charge, and the linearity becomes better as the orbital angular momentum increases. We also prove exactly that the Dirac quasinormal frequencies are the same for opposite chirality.Comment: 10 pages, 6 figures, Phys. Rev. D in pres

Quasinormal modes for massless topological black holes

An exact expression for the quasinormal modes of scalar perturbations on a massless topological black hole in four and higher dimensions is presented. The massive scalar field is nonminimally coupled to the curvature, and the horizon geometry is assumed to have a negative constant curvature.Comment: CECS style, 11 pages, no figures. References adde

Absorption and quasinormal modes of classical fields propagating on 3D and 4D de Sitter spacetime

We extensively study the exact solutions of the massless Dirac equation in 3D de Sitter spacetime that we published recently. Using the Newman-Penrose formalism, we find exact solutions of the equations of motion for the massless classical fields of spin s=1/2,1,2 and to the massive Dirac equation in 4D de Sitter metric. Employing these solutions, we analyze the absorption by the cosmological horizon and de Sitter quasinormal modes. We also comment on the results given by other authors.Comment: 31 page

Nariai, Bertotti-Robinson and anti-Nariai solutions in higher dimensions

We find all the higher dimensional solutions of the Einstein-Maxwell theory that are the topological product of two manifolds of constant curvature. These solutions include the higher dimensional Nariai, Bertotti-Robinson and anti-Nariai solutions, and the anti-de Sitter Bertotti-Robinson solutions with toroidal and hyperbolic topology (Plebanski-Hacyan solutions). We give explicit results for any dimension D>3. These solutions are generated from the appropriate extremal limits of the higher dimensional near-extreme black holes in a de Sitter, and anti-de Sitter backgrounds. Thus, we also find the mass and the charge parameters of the higher dimensional extreme black holes as a function of the radius of the degenerate horizon.Comment: 10 pages, 11 figures, RevTeX4. References added. Published versio

Angular dependence of the bulk nucleation field Hc2 of aligned MgB2 crystallites

Studies on the new MgB2 superconductor, with a critical temperature Tc ~ 39 K, have evidenced its potential for applications although intense magnetic relaxation effects limit the critical current density, Jc, at high magnetic fields. This means that effective pinning centers must be added into the material microstructure, in order to halt dissipative flux movements. Concerning the basic microscopic mechanism to explain the superconductivity in MgB2, several experimental and theoretical works have pointed to the relevance of a phonon-mediated interaction, in the framework of the BCS theory. Questions have been raised about the relevant phonon modes, and the gap and Fermi surface anisotropies, in an effort to interpret spectroscopic and thermal data that give values between 2.4 and 4.5 for the gap energy ratio. Preliminary results on the anisotropy of Hc2 have shown a ratio, between the in-plane and perpendicular directions, around 1.7 for aligned MgB2 crystallites and 1.8 for epitaxial thin films. Here we show a study on the angular dependence of Hc2 pointing to a Fermi velocity anisotropy around 2.5. This anisotropy certainly implies the use of texturization techniques to optimize Jc in MgB2 wires and other polycrystalline components.Comment: 10 pages + 4 Figs.; Revised version accepted in Phys. Rev.

Brane Inflation, Solitons and Cosmological Solutions: I

In this paper we study various cosmological solutions for a D3/D7 system directly from M-theory with fluxes and M2-branes. In M-theory, these solutions exist only if we incorporate higher derivative corrections from the curvatures as well as G-fluxes. We take these corrections into account and study a number of toy cosmologies, including one with a novel background for the D3/D7 system whose supergravity solution can be completely determined. This new background preserves all the good properties of the original model and opens up avenues to investigate cosmological effects from wrapped branes and brane-antibrane annihilation, to name a few. We also discuss in some detail semilocal defects with higher global symmetries, for example exceptional ones, that could occur in a slightly different regime of our D3/D7 model. We show that the D3/D7 system does have the required ingredients to realise these configurations as non-topological solitons of the theory. These constructions also allow us to give a physical meaning to the existence of certain underlying homogeneous quaternionic Kahler manifolds.Comment: Harvmac, 115 pages, 9 .eps figures; v2: typos corrected, references added and the last section expanded; v3: Few minor typos corrected and references added. Final version to appear in JHE

Thermodynamic and gravitational instability on hyperbolic spaces

We study the properties of anti--de Sitter black holes with a Gauss-Bonnet term for various horizon topologies (k=0, \pm 1) and for various dimensions, with emphasis on the less well understood k=-1 solution. We find that the zero temperature (and zero energy density) extremal states are the local minima of the energy for AdS black holes with hyperbolic event horizons. The hyperbolic AdS black hole may be stable thermodynamically if the background is defined by an extremal solution and the extremal entropy is non-negative. We also investigate the gravitational stability of AdS spacetimes of dimensions D>4 against linear perturbations and find that the extremal states are still the local minima of the energy. For a spherically symmetric AdS black hole solution, the gravitational potential is positive and bounded, with or without the Gauss-Bonnet type corrections, while, when k=-1, a small Gauss-Bonnet coupling, namely, \alpha << {l}^2 (where l is the curvature radius of AdS space), is found useful to keep the potential bounded from below, as required for stability of the extremal background.Comment: Shortened to match published (PRD) version, 18 pages, several eps figure