Clinical changes in cats submitted to experimental hyperthyroidism

A relação do hipertireoidismo experimental com parâmetros clínicos foi avaliada em gatos machos e fêmeas, intactos e mantidos em estado hipertireóideo por um período de 42 dias. Os parâmetros estudados foram consumo diário de água e ração, débito urinário, o volume fecal, peso corporal, temperatura corporal, coloração de membranas mucosas, palpação de linfonodos superficiais, palpação da glândula tireóide, pulso femoral, auscultação cardíaca e respiratória, freqüência cardíaca e respiratória e palpação abdominal. Correlacionou-se as variáveis com os níveis de T3 total, T4 livre e total. O excesso dos hormônios tireoidianos acompanhou aumento da freqüência cardíaca, polifagia, polidipsia, perda de peso e aumento do volume fecal nos gatos estudados.The interrelation between experimental hyperthyroidism andclinical changes was studied in adult intact cats kept under hyperthyroidic state for 42 days. Clinical aspects evaluated were dairy food and water intake, urine output and fecal volume, body weight, temperature, mucous membranes colour, palpable lymphnodes, thyroid gland palpation, abdominal palpation, and cardiac and respiratory frequencies. These characteristics were correlated with free and total T4 and total T3 serum concentrations. Excessive circulant thyroid hormone levels resulted in increased cardiac frequency, polyuria, polidipsia, weight loss and increased fecal volume in the studied cats

Epidemiological, clinical and immunohistochemical aspects of canine lymphoma in the region of Porto Alegre, Brazil

This paper describes the epidemiological, clinical and immunohistochemical characteristics of canine lymphomas diagnosed in the region of Porto Alegre, Brazil. Thirty dogs were enrolled in the study; most of them were male (60%), mixed-breed (23%) and middle-aged or older. The majority (87%) of affected dogs showed the multicentric form. The B-cell phenotype was most frequently detected (62%); 37% of the animals were in clinical stage IV, and 83% were classified as sub-stage "b". Lymphadenopathy was observed in 67% of the cases, and dyspnea, prostration, decreased appetite and vomiting were the most common clinical signs encountered. Anemia was a frequently encountered laboratory alteration (57%), as were leukocytosis (40%), thrombocytopenia (33%), lymphopenia (30%), hyperglobulinemia (20%) and hypercalcemia (13%). The results of this study indicate that the clinical features of dogs with lymphoma in the region of Porto Alegre are similar to those observed worldwide

Retrospective study of pre-anesthetic electrocardiogram examination of 700 dogs conducted at the Veterinary Hospital of UFMG (2013-2014)

Abstract: Pre-operative electrocardiograms performed in 700 dogs were analyzed in order to establish correlation between sex, age, indication for surgery, body condition score, breed and weight. Initially a clinical questionnaire was filled out from each owner, including age, breed, sex, weight, clinical history and surgical indication. Dogs above 6 years of age or those showing any kind of cardiac auscultation disturbances were referred to electrocardiogram (ECG) evaluation. All ECG were performed and analyzed by the same veterinary specialist. Abnormalities at ECG were founnd in 364 of 700 (52%) evaluated dogs, and the most frequent variation was sinus arrhythmia, observed in 293 dogs (25.4%). No significant correlation was found between the electrocardiographic alterations with weight, sex and age of the animals. Therefore ECG should be conducted routinely regardless of age, sex, breed or surgical indication, highlighting its value for determining a safe anesthetic protocol that promotes minimal cardiopulmonary depression and allows rapid post-surgical recovery

SINAIS CLÍNICOS DO LINFOMA CANINO

O linfoma é uma neoplasia com origem nos tecidos linfóides sólidos e bastante freqüentes em cães. O objetivo deste trabalho foi descrever os sinais clínicos dos cães com diagnóstico linfoma citológico e/ou histopatológico, atendidos no Hospital Veterinário da FMVZ de Botucatu - SP. Os dados obtidos foram retirados dos prontuários de 54 cães com linfoma, atendidos num período de 28 meses (fevereiro de 1997 a maio de 1999) no referido hospital. A manifestação clínica mais comum foi linfoadenopatia generalizada em 87,04% dos cães. Os sinais clínicos também incluíram apatia (68,52%), perda de peso (68,52%) e hiporexia (42,59%). Os resultados permitem concluir que os sinais clínicos do linfoma canino são variados e inespecíficos. Clinical signs of the canine lymphoma Abstract Canine lymphoma, one of the most frequently detected tumors in dogs, is a neoplasia originating in lymphoid tissues. Over a period of 28 months (February 1997 - May 1999), 54 dogs with diagnosis of lymphoma were evaluated at the Veterinary Hospital of Botucatu, SP. The objective was to describe the clinical findings of dogs with lymphomas. Lymphadenopathy was the clinical finding of highest incidence (87.04%) among the animals studied. Apathy (68.52%), weight loss (68.52%) and hyporexia (42.59%) were the most frequent clinical findings. We conclude that the clinical findings vary as a function of anatomical classification and clinical staging of the tumor

LINFOMA CANINO – ACHADOS CLÍNICO-PATOLÓGICOS

O linfoma é uma neoplasia com origem nos tecidos hematopoiéticos sólidos e é um dos tumores mais freqüentes em cães. Os resultados dos exames laboratoriais obtidos foram retirados dos prontuários de 54 cães com diagnóstico de linfoma, atendidos num período de 28 meses (fevereiro de 1997 a maio de 1999) no Hospital - Botucatu SP. O objetivo foi descrever as alterações hematológicas, do exame de urina e do perfil bioquímico sérico nestes cães. As alterações hematológicas mais freqüentes foram anemia e leucocitose, que ocorreram em 44,44% dos casos. As alterações do exame de urina e do perfil bioquímico sérico foram infreqüentes. O aumento sérico da bilirrubina e das enzimas hepáticas sugerem invasão do fígado por células neoplásicas. A hipercalcemia e hiperglobulinemia foram as síndromes paraneoplásicas suspeitas neste estudo. Conclui-se que os achados bioquímicos e hematológicos do linfoma canino são inespecíficos e variados. Clinical pathologic alterations - canine lymphoma Abstract Canine lymphoma, one of the frequently detected tumors in dogs, is a neoplasia originating in lymphoid tissues. Over a period of 28 months (February 1997 - May 1999) the hematologic, urinalysis and biochemical alterations of 54 dogs with a clinical diagnosis of lymphoma were evaluated at the Veterinary Hospital - Botucatu, SP. Anemia and leukocytosis were the most frequent hematological changes occurring in 44.44% of the cases. Changes in the routine urinalysis or serum clinical chemistry were infrequent. Increased serum levels of bilirubin and liver enzymes suggest invasion of the liver by neoplastic cells. Hypercalcemia and hypergammaglobulinemia were suspected as paraneoplasic syndromes in this study. We conclude that the biochemical and hematological findings of canine lymphoma are nonspecific and variable