10,357 research outputs found
Critical phenomena of thick branes in warped spacetimes
We have investigated the effects of a generic bulk first-order phase
transition on thick Minkowski branes in warped geometries. As occurs in
Euclidean space, when the system is brought near the phase transition an
interface separating two ordered phases splits into two interfaces with a
disordered phase in between. A remarkable and distinctive feature is that the
critical temperature of the phase transition is lowered due to pure geometrical
effects. We have studied a variety of critical exponents and the evolution of
the transverse-traceless sector of the metric fluctuations.Comment: revtex4, 4 pages, 4 figures, some comments added, typos corrected,
published in PR
Custo de utilização de pastagens na Região Sudeste do Brasil.
bitstream/item/65403/1/COT-37-Custo-de-utilizacao-de.pd
Cell death induced by the application of alternating magnetic fields to nanoparticle-loaded dendritic cells
In this work, the capability of primary, monocyte-derived dendritic cells
(DCs) to uptake iron oxide magnetic nanoparticles (MNPs) is assessed and a
strategy to induce selective cell death in these MNP-loaded DCs using external
alternating magnetic fields (AMFs) is reported. No significant decrease in the
cell viability of MNP-loaded DCs, compared to the control samples, was observed
after five days of culture. The amount of MNPs incorporated into the cytoplasm
was measured by magnetometry, which confirmed that 1 to 5 pg of the particles
were uploaded per cell. The intracellular distribution of these MNPs, assessed
by transmission electron microscopy, was found to be primarily inside the
endosomic structures. These cells were then subjected to an AMF for 30 min, and
the viability of the blank DCs (i.e., without MNPs), which were used as control
samples, remained essentially unaffected. However, a remarkable decrease of
viability from approximately 90% to 2-5% of DCs previously loaded with MNPs was
observed after the same 30 min exposure to an AMF. The same results were
obtained using MNPs having either positive (NH2+) or negative (COOH-) surface
functional groups. In spite of the massive cell death induced by application of
AMF to MNP-loaded DCs, the amount of incorporated magnetic particles did not
raise the temperature of the cell culture. Clear morphological changes at the
cell structure after magnetic field application were observed using scanning
electron microscopy. Therefore, local damage produced by the MNPs could be the
main mechanism for the selective cell death of MNP-loaded DCs under an AMF.
Based on the ability of these cells to evade the reticuloendothelial system,
these complexes combined with an AMF should be considered as a potentially
powerful tool for tumour therapy.Comment: In Press. 33 pages, 11 figure
Efeito dos restos culturais do arroz sobre a ocorrência da "mela" e produção de feijão em Rio Branco, AC.
Este trabalho tem como objetivo avaliar o comportamento vegetativo e produtivo de feijão Phaseolus vulgaris L. em cuiltivo a lanço e plantio direto, sopbre os restos culturais do arroz.bitstream/item/145763/1/1150.pd
Tecnologia para a identificação de clones de seringueira (Hevea spp.) por meio de análise de marcadores microssatélites.
Genetic structure and assembling of core collection of tropical forage Calopogonium mucunoides.
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