11 research outputs found

    Etude ARM des veines de la base du crâne (radioanatomie,variantes,images pièges : intérêt des séquences écho de gradient rapide et temps de vol)

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    L'amélioration constante des techniques IRM permet la visualisation d'un nombre croissant de structures vasculaires. En l'absence d'une bonne connaissance radioanatomique, ces images sont source de pièges et d'erreurs. Les séquences que nous avons choisies nous permettent de visualiser les veines cranio-cervicales de la base du crâne et d'étudier leur variabilité. L'ensemble de nos données confirme les quelques études retrouvées dans la littérature et permet d'établir un protocole d'examen IRM applicable dans certaines situations clinique ou en cas de doute diagnostic sur les séquences "standards".ROUEN-BU Médecine-Pharmacie (765402102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

    Pharyngo-larynx carcinologique (bases radio-anatomiques :apport respectif de la TDM et de l'IRM)

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    Le but de ce travail est de préciser l'apport de l'imagerie en carcinologie de la filière pharyngo-laryngée. Nous rappelons tout d'abord les éléments radio-anatomiques utiles, à ne pas méconnaître afin d'interpréter au mieux les aspects radiologiques pathologiques de cette zone anatomique complexe. Nous précisons les protocoles d'imagerie au scanner et en IRM. Pour chaque étage, c'est-à-dire le naso-pharynx, l'oropharynx et le pharyngo larynx, nous rappelons les principales voies d'extension tumorale. Nous insistons, dans le cadre du bilan pré-thérapeutique, sur les éléments utiles au clinicien, afin de guider au mieux sa prise en charge. Pour chacun de ces points, nous précisons l'aspect en imagerie en comparant le scanner et l'IRM. Enfin, dans l'évaluation post-thérapeutique, nous envisageons les modifications classiques, les complications du traitement et leur imagerie et nous proposons une stratégie de surveillance.ROUEN-BU Médecine-Pharmacie (765402102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

    Deep learning analysis of contrast-enhanced spectral mammography to determine histoprognostic factors of malignant breast tumours

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    To evaluate if a deep learning model can be used to characterise breast cancers on contrast-enhanced spectral mammography (CESM)

    Diffusion-Weighted MRI is not superior to FDG-PET/CT for the detection of neck recurrence in well-differentiated thyroid carcinoma.

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    International audienceManagement of patients with well-differentiated thyroid carcinoma (WDTC) and positive Thyroglobulin (Tg) /negative iodine-131 whole body scintigraphy (WBS) remains challenging. Here, we investigate the specific role of diffusion-weighted magnetic resonance imaging of the neck (DW-MRI) as compared to rhTSH stimulated FDG-PET/CT in such patients

    Quantitative MRI to Characterize Hypoxic Tumors in Comparison to FMISO PET/CT for Radiotherapy in Oropharynx Cancers

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    Intratumoral hypoxia is associated with a poor prognosis and poor response to treatment in head and neck cancers. Its identification would allow for increasing the radiation dose to hypoxic tumor subvolumes. 18F-FMISO PET imaging is the gold standard; however, quantitative multiparametric MRI could show the presence of intratumoral hypoxia. Thus, 16 patients were prospectively included and underwent 18F-FDG PET/CT, 18F-FMISO PET/CT, and multiparametric quantitative MRI (DCE, diffusion and relaxometry T1 and T2 techniques) in the same position before treatment. PET and MRI sub-volumes were segmented and classified as hypoxic or non-hypoxic volumes to compare quantitative MRI parameters between normoxic and hypoxic volumes. In total, 13 patients had hypoxic lesions. The Dice, Jaccard, and overlap fraction similarity indices were 0.43, 0.28, and 0.71, respectively, between the FDG PET and MRI-measured lesion volumes, showing that the FDG PET tumor volume is partially contained within the MRI tumor volume. The results showed significant differences in the parameters of SUV in FDG and FMISO PET between patients with and without measurable hypoxic lesions. The quantitative MRI parameters of ADC, T1 max mapping and T2 max mapping were different between hypoxic and normoxic subvolumes. Quantitative MRI, based on free water diffusion and T1 and T2 mapping, seems to be able to identify intra-tumoral hypoxic sub-volumes for additional radiotherapy doses

    Evaluation of the capability and reproducibility of RECIST 1.1. measurements by technologists in breast cancer follow-up: a pilot study

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    Abstract The evaluation of tumor follow-up according to RECIST 1.1 has become essential in clinical practice given its role in therapeutic decision making. At the same time, radiologists are facing an increase in activity while facing a shortage. Radiographic technologists could contribute to the follow-up of these measures, but no studies have evaluated their ability to perform them. Ninety breast cancer patients were performed three CT follow-ups between September 2017 and August 2021. 270 follow-up treatment CT scans were analyzed including 445 target lesions. The rate of agreement of classifications RECIST 1.1 between five technologists and radiologists yielded moderate (k value between 0.47 and 0.52) and substantial (k value = 0.62 and k = 0.67) agreement values. 112 CT were classified as progressive disease (PD) by the radiologists, and 414 new lesions were identified. The analysis showed a percentage of strict agreement of progressive disease classification between reader-technologists and radiologists ranging from substantial to almost perfect agreement (range 73–97%). Analysis of intra-observer agreement was strong at almost perfect (k > 0.78) for 3 technologists. These results are encouraging regarding the ability of selected technologists to perform measurements according to RECIST 1.1 criteria by CT scan with good identification of disease progression
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