Transformações na estrutura produtiva dos viticultores da Serra Gaúcha: 1985/1991.

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Analysis of genetic susceptibility to mercury contamination evaluated through molecular biomarkers in at-risk amazon amerindian populations

We investigated Individual differences in susceptibility to methylmercury (MeHg) contamination and its relationship with polymorphisms of the detoxifying enzyme glutathione S-transferase (GST). In Brazil, some Amerindian tribes from the Amazon region have an increased level of mercury in their hair. Samples of hair and blood were taken from inhabitants of two villages in the Kayabi and Munduruku Amerindian communities to investigate mercury levels in association with genetic polymorphism of GSTs. Other molecular biological markers were also studied, such as hemoglobin, haptoglobin and glucose 6-phosphate dehydrogenase (G-6-PDH). Higher levels of mercury contamination were found in the Kayabi villagers, who had a null genotype (GSTM1 0/0, also denominated GSTM1 null) frequency of 26%, than in the Munduruku villagers, for which the null genotype frequency was 0%. Individuals with the GSTM1 null phenotype had higher concentrations of mercury in their hair than individuals with GSTM1+/+ phenotypes (F = 21.51, p < 0.0001). No association with other markers studied was observed. This study suggests that GSTM1 may be involved in the biotransformation of mercury in humans

Analysis of genetic susceptibility to mercury contamination evaluated through molecular biomarkers in at-risk Amazon Amerindian populations.

Made available in DSpace on 2018-05-31T00:37:32Z (GMT). No. of bitstreams: 1 ID262951.pdf: 65626 bytes, checksum: f3c270df3dbcbcacc1a3ad1f248f1d82 (MD5) Previous issue date: 2005-12-2

Analysis of genetic susceptibility to mercury contamination evaluated through molecular biomarkers in at-risk Amazon Ameridian populations.

Made available in DSpace on 2018-05-31T00:37:32Z (GMT). No. of bitstreams: 1 ID262951.pdf: 65626 bytes, checksum: f3c270df3dbcbcacc1a3ad1f248f1d82 (MD5) Previous issue date: 2005-12-2

Epidemiology of ovine toxoplasmosis and neosporosis in rams from Rio Grande do Sul, Brazil.

Although the State of Rio Grande do Sul is one of the principal sheep rearing regions in Brazil, the prevalence of Toxoplasma gondii and Neospora caninum is unknown in rams. The objective of this study was to determine the prevalence of ovine toxoplasmosis and neosporosis and the risk factors associated with the development of these diseases in rams used exclusively for breeding.September 23-28, 2018

Fatores associados à pneumonia em crianças Yanomami internadas por condições sensíveis à atenção primária na região norte do Brasil

Resumo Em países em desenvolvimento, a pneumonia é a principal causa de adoecimento e morte na infância, principalmente em grupos vulneráveis. O objetivo deste estudo foi analisar os fatores associados à pneumonia em crianças Yanomami internadas por condições sensíveis à atenção primária (ICSAP). As internações foram divididas em dois grupos: i) pneumonias e ii) demais causas, de acordo com a lista brasileira de ICSAP. Foram estimadas taxas ajustadas de ICSAP e utilizou-se a regressão logística não condicional para analisar fatores associados. Mais de 90% dos registros foram considerados ICSAP. A taxa padronizada de ICSAP foi 18,6/1.000. As chances de internação por pneumonia foram 2,7 (IC: 1,3-5,4) vezes maiores em crianças de 0,1 a 5,9 meses; 1,9 (IC: 1,1-3,3) vezes maiores nas crianças que tiveram a duração da hospitalização variando de 8 a 14 dias; e 3,0 (IC: 1,2-7,5) vezes maiores nas crianças com diagnóstico secundário de desnutrição. O excesso de internações evitáveis é um forte indício da baixa qualidade das ações em terras indígenas e do limitado acesso à atenção primária, contrariando o modelo assistencial proposto pelo subsistema de saúde indígena no Brasil que, em tese, deveria privilegiar tecnologias assistenciais ancoradas na atenção primária