Caii Plinii Secundi nouocomensis oratoris facundissimi epistolarum ...

Pie de imp. tomado de colofónSign.: a-n8, m433 línEsp. p. ini

De publicationes epistolarum

Copia digital : Junta de Comunidades de Castilla-La Mancha, 2010Pie de imprenta tomado del colofón, r. de la h. 108Sign.: b8, c10, d-f8, g10, h8, i10, k-l8, m10L. rom.30 lín.Espacios para iniciale

Phylodynamics of HIV-1 Circulating Recombinant Forms 12_BF and 38_BF in Argentina and Uruguay

<p>Abstract</p> <p>Background</p> <p>Although HIV-1 CRF12_BF and CRF38_BF are two epidemiologically important recombinant lineages circulating in Argentina and Uruguay, little is known about their population dynamics.</p> <p>Methods</p> <p>A total of 120 "CRF12_BF-like" and 20 "CRF38_BF-like" <it>pol </it>recombinant sequences collected in Argentina and Uruguay from 1997 to 2009 were subjected to phylogenetic and Bayesian coalescent-based analyses to estimate evolutionary and demographic parameters.</p> <p>Results</p> <p>Phylogenetic analyses revealed that CRF12_BF viruses from Argentina and Uruguay constitute a single epidemic with multiple genetic exchanges among countries; whereas circulation of the CRF38_BF seems to be confined to Uruguay. The mean estimated substitution rate of CRF12_BF at <it>pol </it>gene (2.5 × 10-3 substitutions/site/year) was similar to that previously described for subtype B. According to our estimates, CRF12_BF and CRF38_BF originated at 1983 (1978-1988) and 1986 (1981-1990), respectively. After their emergence, the CRF12_BF and CRF38_BF epidemics seem to have experienced a period of rapid expansion with initial growth rates of around 1.2 year^-1and 0.9 year^-1, respectively. Later, the rate of spread of these CRFs_BF seems to have slowed down since the mid-1990s.</p> <p>Conclusions</p> <p>Our results suggest that CRF12_BF and CRF38_BF viruses were generated during the 1980s, shortly after the estimated introduction of subtype F1 in South America (~1975-1980). After an initial phase of fast exponential expansion, the rate of spread of both CRFs_BF epidemics seems to have slowed down, thereby following a demographic pattern that resembles those previously reported for the HIV-1 epidemics in Brazil, USA, and Western Europe.</p

C. Pli. Caecilii Iunioris Nouocomensis Plinii Secundi veronensis nepotis libri Epistolarum nouem addito nunc et decimo cum Panegyrico in oratione de laudibus Traiani Imperatoris. Una cum luculentissima Ioannis Mariae Catanaei expositione his omnibus libris adiuncta felici sydere incipiunt: quam diligentissime nuper recogniti fidelitirque impressi

El pie de imprenta consta en colofón.Signatura: [cristus]4, a10, b-z8, [parágrafo]6, A-G8Texto con apostillas marginalesPortada con grabados xilográfiados y orla ornametal xilografiad

Liber secundus De mundi historia

Datos de publicación tomados del colofónSign.: A-Z8, a-r8, s

C. Plinii Secundi Novocomensis Epistolarum libri X. Panegyricus Traiano principi dictus. De viris illustribus in re militari. & in administranda Rep. Item Suetonii Tranquilli de claris grammaticis et rhetoribus. Iulii obsequentis Prodigiorum liber. Indices duo quorum altero nomina referuntur eorum, ad quos Plinius secribit, altero quicquiid memoratu dignum ... continetur. Latina interprtetatio dictionum & sententiarum Graecarum quibus Plinius utitur

Copia digital. Madrid : Ministerio de Educación, Cultura y Deporte. Subdirección General de Coordinación Bibliotecaria, 2013El lugar de impresión y el impresor constan en el colofónMarca tip. al final de la obraSign.: a-z8, A-D8Letras capitales ornada