Sprouting and Growth studies of Rose (Rosa) and Hibiscus (Hibiscus rosasinenis) flowering plants irrigated by distillery spentwash

Sprouting and growth of Rose (Rosa) and Hibiscus (Hibiscus rosasinenis) flowering plants was made by irrigated with distillery spentwash of different concentrations. Thespentwash i.e., primary treated spentwash (PTSW), 1:1, 1:2, and 1:3 spent wash were analyzedfor their plant nutrients such as nitrogen, phosphorous, potassium and other physical andchemical characteristics. Experimental soil was tested for its chemical and physical parameters.Rose and Hibiscus sets were planted in different pots and irrigated with raw water (RW), 1:1,1:2 and 1:3 spentwash. The nature of sprouting and growth was studied. It was found that thesprouting and growth of both plants was very good (100%) in 1:3 SW irrigation, while very poor(25%) in 1:1 SW, moderate (80%) in 1:2 SW and 95% in RW irrigation growth

Study of parameters of CSR-2 cocoon reared with V1 mulberry leaves irrigated by spentwash

CSR-2 silkworm reared with V1 variety of mulberry plants irrigated by raw water,50% PTSW and 33% PTSW. The different parameters such as raw silk (%), filamentlength (m), reelability (%), denier and shell ratio were determined at the maturity ofcocoons. It was found that the parameters werebetter in cocoon irrigated with 33%PTSWcompared to 50%PTSW and raw water irrigations. This concludes that the mulberryplants irrigated with 33%PTSW is enriched with more nutrients for the potential growthof mulberry plants which results in the potential cocoons

Stabilization of a Highly Concentrated Colloidal Suspension of Pristine Metallic Nanoparticles

A colloidal suspension containing a high concentration of metallic nanoparticles (NPs) finds potential applications in flexible electronic printing, nanofluids, healthcare, antifouling coating, and so on. Here, we demonstrate a generic, easily scalable, simple, and contamination-free cryogenic temperature grinding method, which can effectively be used to prepare pristine NPs that can be stabilized in polar liquids in high concentrations. These surfactant-free pristine NPs have been found to remain dispersed in different polar liquids (CH3OH, C2H5OH, glycol, etc.) for weeks. The long-term stability of the NPs in these liquids has been investigated using zeta potential, in situ Fourier transform infrared spectroscopy, indicating electrostatic stabilization for ultrapure, surfactant-free NPs. Furthermore, stabilization of the NPs has been probed with detailed calculations using the Derjaguin Landau Verwey Overbeek theory as well as atomistic molecular dynamics simulation (MD). Experimental measurements along with theoretical calculations categorically indicate that the electrostatic energy is helping these NPs to be stabilized in a polar liquid

Depolymerization of bagasse by Ruminococcus albus in the production of eco-friendly fuel

Ethanol production by fermentation of lignocellulosic biomass-derived sugars involves a fairly ancient art and an ever-evolving science. Production of ethanol from lignocellulosic biomass is not avant-garde, and wood ethanol plants have been in existence since at least 1915. Most current ethanol production relies on starch- and sugarbased crops as the substrate; however, limitations of these materials and competing value for human and animal feeds is renewing interest in lignocellulose  conversion.Lignocellulosic biomass contains carbohydrate fractions that can be converted into ethanol. In order to convert these fractions, the cellulose and hemicelluloses must ultimately be converted or hydrolysed into monosaccharides; it is the hydrolysis that has historically proven to be problematic. Biologically mediated processes are promising for energy conversion, in particular for the conversion of lignocellulosic biomass into  fuels. The objective of the present study is to optimise cellulosic ethanol production from bagasse by using Ruminococcus albus isolated from rumen of herbivores animals. The processing and utilization of the  lignocellulosic substrate is complex, differing in many aspects from crop-based ethanol production. Since the scientific dogma states that the breakdown or depolymerisation of lignocellulose can be achieved only by chemical or by enzymatic approach; in the present study we isolated Ruminococcus albus from rumen animals which was depolymerise cellulose and hemicellulose as well as to tolerate stress conditions. Optimum temperature, pH and substrate concentration for depolymerization were 390C, 8.8 and 3.5% respectively for Ruminococcus albus. For the feed  stock of concentration 3.5%, ethanol yield of 19.8g/l was obtained

Synthesis of Novel 3-Aryl-N-Methyl-1,2,5,6-Tetrahydropyridine Derivatives by Suzuki coupling: As Acetyl Cholinesterase Inhibitors

Alzheimer’s disease (AD) is a neurodegenerative disorder affecting the central nervous system, which is also associated with progressive loss of memory and cognition. The development of numerous structural classes of compounds with different pharmacological profile could be an evolving, promising therapeutic approach for the treatment of AD. Thus, providing a symptomatic treatment for this disease are cholinomimetics with the pharmacological profile of Acetylcholinesterase (AChE) inhibitors. In view of this, we have synthesized novel 3-aryl-N-methyl-1,2,5,6-tetrahydropyridine derivatives 5a-k by Suzuki coupling and screened the efficacy of these derivatives for their AChE inhibitor activity

Anti-tumor and anti-angiogenic activity of novel hydantoin derivatives: Inhibition of VEGF secretion in liver metastatic osteosarcoma cells

A series of new azaspiro bicyclic hydantoin derivatives has been designed and synthesized. Initially, the anti-proliferative effect of the hydantoin derivatives was evaluated against human ovarian cancer cells (SKOV-3 and OVSAHO) and murine osteosarcoma cells (LM8 and LM8G7). Among the tested compounds, 8-(3-fluorobenzyl)-1′-(4-(methylsulfonyl)benzyl)-8-azaspiro[bicyclo[3.2.1]octane-3,4′-imidazolidine]-2′,5′-dione (7h) and 8-(3,4-difluorobenzyl)-1′-(4-(methylsulfonyl)benzyl)-8-azaspiro[bicyclo[3.2.1]octane-3,4′-imidazolidine]-2′,5′-dione (7i) showed a significant anti-proliferative activity against the OVSAHO and LM8G7 cells. The real-time monitoring of the effect of the compounds 7h and 7i against the proliferation of LM8G7 was revealed that resulting IC50 values were 102 μM and 13 μM, respectively. We reasoned that the presence of fluorine atom at the 3rd position of the phenyl ring of the hydantoin side chain may determine the potency of the molecule. Furthermore, the compound 7i inhibited the tube formation of the mouse endothelial cells. Finally, the treatment of the compound 7i against the proliferation of LM8G7 cells demonstrated the down regulation of the secretion of VEGF, indicate the potential angioinhibitory effects. In conclusion, our findings demonstrate the suppression of the secretion of VEGF by LM8G7 cells by the compound 7i might contribute at least in part to the antitumor action