Microscopic calculation of the spin-dependent neutron scattering lengths on 3He

We report on the spin.dependent neutron scattering length on 3He from a microscopic calculation of p-3H, n-3He, and d-2H scattering employing the Argonne v18 nucleon-nucleon potential with and without additional three-nucleon force. The results and that of a comprehensive R-matrix analysis are compared to a recent measurement. The overall agreement for the scattering lengths is quite good. The imaginary parts of the scattering lengths are very sensitive to the inclusion of three-nucleon forces, whereas the real parts are almost insensitive.Comment: 9 pages, 1 figur

Universal Correlations in Pion-less EFT with the Resonating Group Model: Three and Four Nucleons

The Effective Field Theory "without pions" at next-to-leading order is used to analyze universal bound state and scattering properties of the 3- and 4-nucleon system. Results of a variety of phase shift equivalent nuclear potentials are presented for bound state properties of 3H and 4He, and for the singlet S-wave 3He-neutron scattering length a_0(3He-n). The calculations are performed with the Refined Resonating Group Method and include a full treatment of the Coulomb interaction and the leading-order 3-nucleon interaction. The results compare favorably with data and values from AV18(+UIX) model calculations. A new correlation between a_0(3He-n) and the 3H binding energy is found. Furthermore, we confirm at next-to-leading order the correlations, already found at leading-order, between the 3H binding energy and the 3H charge radius, and the Tjon line. With the 3H binding energy as input, we get predictions of the Effective Field Theory "without pions" at next-to-leading order for the root mean square charge radius of 3H of (1.6\pm 0.2) fm, for the 4He binding energy of (28\pm 2.5) MeV, and for Re(a_0(3He-n)) of (7.5\pm 0.6)fm. Including the Coulomb interaction, the splitting in binding energy between 3H and 3He is found to be (0.66\pm 0.03) MeV. The discrepancy to data of (0.10\mp 0.03) MeV is model independently attributed to higher order charge independence breaking interactions. We also demonstrate that different results for the same observable stem from higher order effects, and carefully assess that numerical uncertainties are negligible. Our results demonstrate the convergence and usefulness of the pion-less theory at next-to-leading order in the 4He channel. We conclude that no 4-nucleon interaction is needed to renormalize the theory at next-to-leading order in the 4-nucleon sector.Comment: 24 pages revtex4, including 8 figures as .eps files embedded with includegraphicx, leading-order results added, calculations include the LO three-nucleon interaction explicitly, comment on Wigner bound added, minor modification

Dexamethasone intravitreal implant in previously treated patients with diabetic macular edema : Subgroup analysis of the MEAD study

Background: Dexamethasone intravitreal implant 0.7 mg (DEX 0.7) was approved for treatment of diabetic macular edema (DME) after demonstration of its efficacy and safety in the MEAD registration trials. We performed subgroup analysis of MEAD study results to evaluate the efficacy and safety of DEX 0.7 treatment in patients with previously treated DME. Methods: Three-year, randomized, sham-controlled phase 3 study in patients with DME, best-corrected visual acuity (BCVA) of 34.68 Early Treatment Diabetic Retinopathy Study letters (20/200.20/50 Snellen equivalent), and central retinal thickness (CRT) 65300 \u3bcm measured by time-domain optical coherence tomography. Patients were randomized to 1 of 2 doses of DEX (0.7 mg or 0.35 mg), or to sham procedure, with retreatment no more than every 6 months. The primary endpoint was 6515-letter gain in BCVA at study end. Average change in BCVA and CRT from baseline during the study (area-under-the-curve approach) and adverse events were also evaluated. The present subgroup analysis evaluated outcomes in patients randomized to DEX 0.7 (marketed dose) or sham based on prior treatment for DME at study entry. Results: Baseline characteristics of previously treated DEX 0.7 (n = 247) and sham (n=261) patients were similar. In the previously treated subgroup, mean number of treatments over 3 years was 4.1 for DEX 0.7 and 3.2 for sham, 21.5 % of DEX 0.7 patients versus 11.1 % of sham had 6515-letter BCVA gain from baseline at study end (P = 0.002), mean average BCVA change from baseline was +3.2 letters with DEX 0.7 versus +1.5 letters with sham (P = 0.024), and mean average CRT change from baseline was -126.1 \u3bcm with DEX 0.7 versus -39.0 \u3bcm with sham(P < 0.001). Cataract-related adverse events were reported in 70.3 % of baseline phakic patients in the previously treated DEX 0.7 subgroup; vision gains were restored following cataract surgery. Conclusions: DEX 0.7 significantly improved visual and anatomic outcomes in patients with DME previously treated with laser, intravitreal anti-vascular endothelial growth factor, intravitreal triamcinolone acetonide, or a combination of these therapies. The safety profile of DEX 0.7 in previously treated patients was similar to its safety profile in the total study population

Ação do fungo Metarhizium anisopliae sobre desenvolvimento do díptero Muscina stabulans em laboratório Action of Metarhizium anisopliae fungi over the development of Muscina stabulans dipteran in laboratory

Avaliou-se o desenvolvimento de Muscina stabulans (Diptera, Muscidae) após exposição ao fungo Metarhizium anisopliae (isolado CG34), sob condições de laboratório. Suspensões de esporos foram preparadas nas concentrações de 10(5), 10(6), 10(7) e 10(8)conídeos/mL-1. Noventa larvas pós-alimentar por tratamento, distribuídas em cinco tratamentos e três repetições, foram mergulhadas por um segundo nas respectivas suspensões, transferidas para placas de Petri com papel filtro umedecido e mantidas em estufa BOD à temperatura de 25ºC, umidade relativa de 80% e fotoperíodo de 12:12 horas até a emergência dos adultos. Foram avaliados a taxa de mortalidade pupal e o período de desenvolvimento pupal. As larvas apresentaram suscetibilidade à ação de M. anisopliae em diferentes concentrações. A mortalidade pupal assim como o tempo de desenvolvimento das pupas (de 8,8 a 10 dias) aumentaram conforme o aumento da concentração de conídios (de zero a 47%). A aplicação de M. anisopliae nesta fase do ciclo biológico comprometeu o desenvolvimento de M. stabulans e interferiu no controle natural de pragas que se desenvolvem no mesmo ambiente.The development of Muscina stabulans (Diptera, Muscidae) after exposure to Metarhizium anisopliae (CG34 isolated) fungi under laboratory conditions was evaluated. Suspensions of spores were prepared in concentrations of 10(5), 10(6), 10(7), and 10(8)conidia/mL-1. Ninety postfeeding larvae per treatment, divided into five treatments and three repetitions, were dived for one second in the respective suspensions, and transferred to Petri dishes with humidified filter paper and maintained in BOD at 25 ºC with 80% relative humidity and a 12:12h photoperiod, until the emergency of adults. The rate of pupal mortality and the period of pupal development were evaluated. The larvae showed susceptibility to the action of M. anisopliae in different levels of concentration. The pupal mortality increased accordingly to the increase in the conidia concentration (from zero to 47%), as well as prolonged the time of development of the pupae (from 8.8 to 10 days). The application of M. anisopliae in this phase of the biological cycle compromised the development of M. stabulans and interfered in the natural control of pests that develop in the same environment

EFEITOS DA COMPETIÇÃO LARVAL INTRA-ESPECÍFICA SOBRE CARACTERES BIOMÉTRICOS DE MUSCINA STABULANS (FALLÉN, 1817) (DIPTERA: MUSCIDAE) EM LABORATÓRIO

RESUMO O objetivo do trabalho foi investigar o efeito da competição intra-específica sobre características biométricas de Muscina stabulans (Fallén, 1817) (Diptera, Muscidae) em condições controladas de laboratório com a finalidade de aprimorar criações desta espécie. Dez densidades, a intervalos de 100, na faixa de 100 a 1.000 larvas foram colocadas em 50 g de substrato alimentar, e seu desenvolvimento foi acompanhado até a fase adulta. A alta densidade de larvas de M. stabulans reduz a viabilidade de larvas, peso das pupas e prolonga o período de desenvolvimento larval. Foi observado que a emergência decresceu em função da densidade larval, reduzindo também peso das fêmeas, fecundidade e investimento reprodutivo. Altos níveis de competição larval produzem adultos pequenos e de baixa fecundidade.</jats:p

INFLUÊNCIA DA DIETA NO DESENVOLVIMENTO E INVESTIMENTO REPRODUTIVO DE CHRYSOMYA MEGACEPHALA (FABRICIUS, 1794) (DIPTERA: CALLIPHORIDAE)

RESUMO A dificuldade de manter-seChrysomya megacephala em laboratório está na rápida putrefação dos meios utilizados para sua criação. Para tal, o presente trabalho visou testar sob condições controladas duas dietas: peixe in natura e um meio artificial constituído por farinha de carne, serragem e água. Foram montadas três repetições, para cada dieta, com 200 larvas cada, onde observou-se que o meio constituído por peixe in natura apresentou menor período de desenvolvimento (8 dias), emergência dos adultos de 83,3%, peso médio das fêmeas fecundas de 65,185 mg, média de 220,722 ovos por fêmea, investimento reprodutivo de 3,599 e taxa de infecundidade de 43,3%. O meio artificial apresentou um período maior (10 dias), a emergência dos adultos foi de 86%, o peso médio das fêmeas fecundas foi de 64,882 mg, média de 218,515 ovos por fêmea, investimento reprodutivo de 3,364 e taxa de infecundidade de 24,4%. Verificou-se, em ambas dietas, que houve índice de relação diretamente proporcional entre o peso e o número de ovos por fêmea, concluindo-se que a dieta influi na fecundidade das fêmeas de C. megacephala.</jats:p