The effect of a founding International Baccalaureate Middle Years Programme on participating seventh grade students\u27 achievement, behavior, extra-curricular involvement, and perceptions of life skills

The purpose of this study was to determine the effect of a founding International Baccalaureate Middle Years Programme (IBMYP) on participating 7th-grade students\u27 achievement, behavior, extra-curricular involvement, and perceptions of life skills compared to 7th-grade students\u27 completing the same school\u27s standard of care traditional academic program (TAP). The study analyzed data of IBMYP and TAP students to determine if the IBMYP has significantly impacted student outcomes. Following two consecutive years of program participation IBMYP students (n = 30) demonstrated a significant pretest-posttest improvement on norm-referenced achievement test math scores but their measured language and reading achievement test scores remained consistent over this same time period. TAP students (n = 30) demonstrated no significant math, language, and reading pretest-posttest gain on norm-referenced achievement tests. IBMYP students\u27 math, language, and reading norm-referenced achievement test scores were statistically significantly greater than their TAP peers on all Posttest-Posttest comparisons. On locally developed criterion-referenced tests, both groups showed significant pretest-posttest gains in math, and the IBMYP students also showed significant gains in reading. In posttest-posttest comparisons, IBMYP students\u27 scores were statistically significantly greater on each of the test comparisons. There were no significant differences between the groups in student absence, or in self-perceptions of student life skills, but there was a significantly higher amount of extra-curricular involvement among IBMYP students. In light of the study results, local policy makers should consider expansion of the program

Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution

The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties impact the evolution of repeats and genes, we manually improved the sequence and annotated the genes on the D. erecta, D. mojavensis, and D. grimshawi F elements and euchromatic domains from the Muller D element. We find that F elements have greater transposon density (25-50%) than euchromatic reference regions (3-11%). Among the F elements, D. grimshawi has the lowest transposon density (particularly DINE-1: 2% vs. 11-27%). F element genes have larger coding spans, more coding exons, larger introns, and lower codon bias. Comparison of the Effective Number of Codons with the Codon Adaptation Index shows that, in contrast to the other species, codon bias in D. grimshawi F element genes can be attributed primarily to selection instead of mutational biases, suggesting that density and types of transposons affect the degree of local heterochromatin formation. F element genes have lower estimated DNA melting temperatures than D element genes, potentially facilitating transcription through heterochromatin. Most F element genes (~90%) have remained on that element, but the F element has smaller syntenic blocks than genome averages (3.4-3.6 vs. 8.4-8.8 genes per block), indicating greater rates of inversion despite lower rates of recombination. Overall, the F element has maintained characteristics that are distinct from other autosomes in the Drosophila lineage, illuminating the constraints imposed by a heterochromatic milieu. Keywords: codon bias; evolution of heterochromatin; gene size; melting characteristics; transposons

Attitudes and training of research fellows in surgery: national questionnaire survey

We examined the views of research fellows towards research and investigated whether the recommendations of the Calman report on research and surgical training had been adhered to

Quenching Effects in the Hadron Spectrum

Lattice QCD has generated a wealth of data in hadronic physics over the last two decades. Until relatively recently, most of this information has been within the "quenched approximation" where virtual quark--anti-quark pairs are neglected. This review presents a descriptive discussion of the effects of removing this approximation in the calculation of hadronic masses.Comment: To appear in "Lattice Hadron Physics", ed. A.C. Kalloniatis, D.B. Leinweber and A.G. William

OnRamp: a Galaxy-based platform for collaborative annotation of eukaryotic genomes

G-OnRamp provides a user-friendly, web-based platform for collaborative, end-to-end annotation of eukaryotic genomes using UCSC Assembly Hubs and JBrowse/Apollo genome browsers with evidence tracks derived from sequence alignments, ab initio gene predictors, RNA-Seq data and repeat finders. G-OnRamp can be used to visualize large genomics datasets and to perform collaborative genome annotation projects in both research and educational settings

Is Cycle 24 the Beginning of a Dalton-Like Minimum?

The unexpected development of cycle 24 emphasizes the need for a better way to model future solar activity. In this article, we analyze the accumulation of spotless days during individual cycles from 1798-2010. The analysis shows that spotless days do not disappear abruptly in the transition towards an active sun. A comparison with past cycles indicates that the ongoing accumulation of spotless days is comparable to that of cycle 5 near the Dalton minimum and to that of cycles 12, 14 and 15. It also suggests that the ongoing cycle has as much as 20 \pm 8 spotless days left, from July 2010, before it reaches the next solar maximum. The last spotless day is predicted to be in December 2012, with an uncertainty of 11 months. This trend may serve as input to the solar dynamo theories.Comment: 10 pages, 5 figures. The final publication is available at http://www.springerlink.co