421 research outputs found

    Tax Cuts and Employment Growth in New Jersey: Lessons from a Regional Analysis

    Get PDF
    The Whitman Administration’s 30 percent reduction in New Jersey’s personal income taxes from 1994-96 is prominently cited as a role model for state fiscal policy. We investigate whether the growth benefits attributed to the Whitman tax cuts are warranted. Panel data methods are applied to annual observations of county-level employment growth from New Jersey and the surrounding economic region. Our analysis does not support the hypothesis that tax cuts stimulated employment growth in New Jersey. While New Jersey did experience substantial employment growth subsequent to the tax cuts, most of this growth was shared by the nearby Economic Areas

    On the most compact regular lattice in large dimensions: A statistical mechanical approach

    Full text link
    In this paper I will approach the computation of the maximum density of regular lattices in large dimensions using a statistical mechanics approach. The starting point will be some theorems of Roger, which are virtually unknown in the community of physicists. Using his approach one can see that there are many similarities (and differences) with the problem of computing the entropy of a liquid of perfect spheres. The relation between the two problems is investigated in details. Some conjectures are presented, that need further investigation in order to check their consistency.Comment: 27 page

    Undervalued and ignored:Are humans poorly adapted to energy-dense foods?

    Get PDF
    In many species the capacity to accurately differentiate the energy density (kcal/g) of foods is critical because it greatly improves efficiency in foraging. In modern humans this ability remains intact and is expressed in a selective preference for types of fruit and vegetables that contain more calories. However, humans evolved consuming these low energy-dense foods (typically < 1.75 kcal/g) and it remains unclear whether they can also discriminate more energy-dense foods that now feature in modern Western diets. In two experiment participants (both N = 40) completed four tasks that assessed the ‘value’ of different sets of 22 foods that ranged in energy density (0.1 kcal/g–5.3 kcal/g and range 0.1 kcal/g to 6.2 kcal/g in Experiment 1 and 2, respectively). In Experiment 1 three measures (expected fullness, calorie estimation, and food choice), and in foods less than approximately 1.5 kcal/g (typically fruits and vegetables), the relationship between perceived value and energy density is linear. Above this, we observed clear compressive functions, indicating relative and progressive undervaluation of higher energy-dense foods. The fourth task (rated liking) failed to provide evidence for any relationship with energy density. In Experiment 2 the same pattern was replicated in measures of expected fullness, and in two different assessments of subjective calorie content. Consistent with the concept of ‘evolutionary discordance,’ this work indicates that modern human physiology is poorly adapted to evaluate foods that have a historically unusual (high) energy density. This has implications both for our understanding of how ‘modern’ energy-dense foods affect choice and energy intake, and for strategies aimed at removing calories from highly energy-rich foods

    Interpreting Helioseismic Structure Inversion Results of Solar Active Regions

    Full text link
    Helioseismic techniques such as ring-diagram analysis have often been used to determine the subsurface structural differences between solar active and quiet regions. Results obtained by inverting the frequency differences between the regions are usually interpreted as the sound-speed differences between them. These in turn are used as a measure of temperature and magnetic-field strength differences between the two regions. In this paper we first show that the "sound-speed" difference obtained from inversions is actually a combination of sound-speed difference and a magnetic component. Hence, the inversion result is not directly related to the thermal structure. Next, using solar models that include magnetic fields, we develop a formulation to use the inversion results to infer the differences in the magnetic and thermal structures between active and quiet regions. We then apply our technique to existing structure inversion results for different pairs of active and quiet regions. We find that the effect of magnetic fields is strongest in a shallow region above 0.985R_sun and that the strengths of magnetic-field effects at the surface and in the deeper (r < 0.98R_sun) layers are inversely related, i.e., the stronger the surface magnetic field the smaller the magnetic effects in the deeper layers, and vice versa. We also find that the magnetic effects in the deeper layers are the strongest in the quiet regions, consistent with the fact that these are basically regions with weakest magnetic fields at the surface. Because the quiet regions were selected to precede or follow their companion active regions, the results could have implications about the evolution of magnetic fields under active regions.Comment: Accepted for publication in Solar Physic

    Women, men and coronary heart disease: a review of the qualitative literature

    Get PDF
    Aim. This paper presents a review of the qualitative literature which examines the experiences of patients with coronary heart disease. The paper also assesses whether the experiences of both female and male patients are reflected in the literature and summarizes key themes. Background. Understanding patients' experiences of their illness is important for coronary heart disease prevention and education. Qualitative methods are particularly suited to eliciting patients' detailed understandings and perceptions of illness. As much previous research has been 'gender neutral', this review pays particular attention to gender. Methods. Published papers from 60 qualitative studies were identified for the review through searches in MEDLINE, EMBASE, CINAHL, PREMEDLINE, PsychINFO, Social Sciences Citation Index and Web of Science using keywords related to coronary heart disease. Findings. Early qualitative studies of patients with coronary heart disease were conducted almost exclusively with men, and tended to generalize from 'male' experience to 'human' experience. By the late 1990s this pattern had changed, with the majority of studies including women and many being conducted with solely female samples. However, many studies that include both male and female coronary heart disease patients still do not have a specific gender focus. Key themes in the literature include interpreting symptoms and seeking help, belief about coronary 'candidates' and relationships with health professionals. The influence of social roles is important: many female patients have difficulties reconciling family responsibilities and medical advice, while male patients worry about being absent from work. Conclusions. There is a need for studies that compare the experiences of men and women. There is also an urgent need for work that takes masculinity and gender roles into account when exploring the experiences of men with coronary heart disease

    First Stars. I. Evolution without mass loss

    Full text link
    The first generation of stars was formed from primordial gas. Numerical simulations suggest that the first stars were predominantly very massive, with typical masses M > 100 Mo. These stars were responsible for the reionization of the universe, the initial enrichment of the intergalactic medium with heavy elements, and other cosmological consequences. In this work, we study the structure of Zero Age Main Sequence stars for a wide mass and metallicity range and the evolution of 100, 150, 200, 250 and 300 Mo galactic and pregalactic Pop III very massive stars without mass loss, with metallicity Z=10E-6 and 10E-9, respectively. Using a stellar evolution code, a system of 10 equations together with boundary conditions are solved simultaneously. For the change of chemical composition, which determines the evolution of a star, a diffusion treatment for convection and semiconvection is used. A set of 30 nuclear reactions are solved simultaneously with the stellar structure and evolution equations. Several results on the main sequence, and during the hydrogen and helium burning phases, are described. Low metallicity massive stars are hotter and more compact and luminous than their metal enriched counterparts. Due to their high temperatures, pregalactic stars activate sooner the triple alpha reaction self-producing their own heavy elements. Both galactic and pregalactic stars are radiation pressure dominated and evolve below the Eddington luminosity limit with short lifetimes. The physical characteristics of the first stars have an important influence in predictions of the ionizing photon yields from the first luminous objects; also they develop large convective cores with important helium core masses which are important for explosion calculations.Comment: 17 pages, 24 figures, 2 table

    Analysis of microstructure effects on edge crack of thin strip during cold rolling

    Get PDF
    Edge cracks in cold rolling of the thin strip affect the strip quality and productivity significantly. In this study, an experimental and mechanical investigation on microstructures has been carried out to study the edge crack formation during cold rolling of the thin strip. The effects of the feed material microstructures on the edge crack evolution were studied employing optical microscopy and scanning electron microscopy (SEM). Experimental observation indicates that fine grain occurs in hot-rolled microstructure and coarse grain is produced in ferritic rolled microstructure. Different grain sizes affect significantly the formation mechanics of the microcrack, crack initiation, and orientation of crack extension. The grain size and grain boundaries effects on crack retardation are discussed also during edge crack initiation. During the crack growth in coarse grain, most edge crack tips will blunt, which improves the crack toughness by causing less stress concentration. Overall, the fine microstructure shows a good crack initiation resistance, whereas the coarse microstructure has a better resistance to crack propagation. This research provides additional understanding of the mechanism of microstructure influence on edge crack evolution of cold strip rolling, which could be helpful for developing defect-free thin strip

    Pharmacognostical Sources of Popular Medicine To Treat Alzheimer’s Disease

    Get PDF

    Animal models for COVID-19

    Get PDF
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the introduction of a novel coronavirus into humans late in 2019 (first detected in Hubei province, China). As of 18 September 2020, SARS-CoV-2 has spread to 215 countries, has infected more than 30 million people and has caused more than 950,000 deaths. As humans do not have pre-existing immunity to SARS-CoV-2, there is an urgent need to develop therapeutic agents and vaccines to mitigate the current pandemic and to prevent the re-emergence of COVID-19. In February 2020, the World Health Organization (WHO) assembled an international panel to develop animal models for COVID-19 to accelerate the testing of vaccines and therapeutic agents. Here we summarize the findings to date and provides relevant information for preclinical testing of vaccine candidates and therapeutic agents for COVID-19

    The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial

    Get PDF
    Objectives: To determine if lopinavir/ritonavir +/- hydroxychloroquine will reduce the proportion of participants who survive without requiring ventilatory support, 15 days after enrolment, in adult participants with non-critically ill SARS-CoV-2 infection. Trial design: ASCOT is an investigator-initiated, multi-centre, open-label, randomised controlled trial. Participants will have been hospitalised with confirmed COVID-19, and will be randomised 1:1:1:1 to receive lopinavir /ritonavir, hydroxychloroquine, both or neither drug in addition to standard of care management. Participants: Participants will be recruited from >80 hospitals across Australia and New Zealand, representing metropolitan and regional centres in both public and private sectors. Admitted patients will be eligible if aged ≥ 18 years, have confirmed SARS-CoV-2 by nucleic acid testing in the past 12 days and are expected to remain an inpatient for at least 48 hours from the time of randomisation. Potentially eligible participants will be excluded if admitted to intensive care or requiring high level respiratory support, are currently receiving study drugs or their use is contraindicated due to allergy, drug interaction or comorbidities (including baseline QTc prolongation of 470ms for women or 480ms for men), or death is anticipated imminently
    corecore