952 research outputs found
Leaf Extracts of Calocedrus formosana (Florin) Induce G2/M Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells
Calocedrus formosana (Florin) bark acetone/ethylacetate extracts are known to exert an antitumor effect on some human cancer cell lines, but the mechanism is yet to be defined. The aim of this study was to determine the effects of Florin leaf methanol extracts on the growth and apoptosis of human bladder cancer cell lines. MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay showed that the growth of these bladder cancer cells was potently inhibited by the Florin leaf extracts. The cell cycle of these extract-treated cells (TCCSUP cells) was arrested at the G2/M phase as determined by flow cytometry. Western blot analysis revealed the increases of cyclin B1 and Cdc2 kinase levels, alone with the decrease of phosphorylated Cdc2 kinase, after treating these cells with the extracts. An immunofluorescence assessment of β-tubulin showed decreased levels of polymerized tubulin in treated cells. However, the proteolytic cleavage of poly ADP-ribose polymerase and the activation of caspase-3/-8/-9 were all increased upon treatments of extracts. The concurrent increase of Bax and decrease of Bcl-2 levels indicated that the extracts could induce apoptosis in these treated cells. Taken together, these results suggest that the Florin leaf extracts may be an effective antibladder cancer agent
Kinetic energy driven superconductivity in doped cuprates
Within the t-J model, the mechanism of superconductivity in doped cuprates is
studied based on the partial charge-spin separation fermion-spin theory. It is
shown that dressed holons interact occurring directly through the kinetic
energy by exchanging dressed spinon excitations, leading to a net attractive
force between dressed holons, then the electron Cooper pairs originating from
the dressed holon pairing state are due to the charge-spin recombination, and
their condensation reveals the superconducting ground-state. The electron
superconducting transition temperature is determined by the dressed holon pair
transition temperature, and is proportional to the concentration of doped holes
in the underdoped regime. With the common form of the electron Cooper pair, we
also show that there is a coexistence of the electron Cooper pair and
antiferromagnetic short-range correlation, and hence the antiferromagnetic
short-range fluctuation can persist into the superconducting state. Our results
are qualitatively consistent with experiments.Comment: 6 pages, Revtex, two figures are included, corrected typo
Scaling predictions for radii of weakly bound triatomic molecules
The mean-square radii of the molecules He, HeLi,
HeLi and HeNa are calculated using a three-body model
with contact interactions. They are obtained from a universal scaling function
calculated within a renormalized scheme for three particles interacting through
pairwise Dirac-delta interaction. The root-mean-square distance between two
atoms of mass in a triatomic molecule are estimated to be of de order of
, where is the dimer and the
trimer binding energies, and is a constant (varying from
to ) that depends on the ratio between and . Considering
previous estimates for the trimer energies, we also predict the sizes of
Rubidium and Sodium trimers in atomic traps.Comment: 7 pages, 2 figure
Anomalous c-axis charge dynamics in copper oxide materials
Within the t-J model, the c-axis charge dynamics of the copper oxide
materials in the underdoped and optimally doped regimes is studied by
considering the incoherent interlayer hopping. It is shown that the c-axis
charge dynamics is mainly governed by the scattering from the in-plane
fluctuation. In the optimally doped regime, the c-axis resistivity is a linear
in temperatures, and shows the metallic-like behavior for all temperatures,
while the c-axis resistivity in the underdoped regime is characterized by a
crossover from the high temperature metallic-like behavior to the low
temperature semiconducting-like behavior, which are consistent with experiments
and numerical simulations.Comment: 6 pages, Latex, Three figures are adde
Managing to lead in private enterprise in China: Work values, demography and the development of trust
Previous work on trust has focused on employee trust in management. However, issues of how leaders develop trust in their followers in leader-member exchange (LMX) are under-explored. Based on theories of leader-member exchange, attribution and industrial convergence, this study investigates how the work values of leaders influence the development of their trust in followers and how this is moderated by demographic factors. A survey of 219 leaders was conducted in privately owned enterprises in China. The findings suggest that the work value of centralization is negatively related to leader trust in follower predictability. Group orientation and formalization are positively related to the development of trust in follower good faith. Moreover, age and level of formal education are found to moderate significantly the relationships between leader work values and development of their trust in followers within the context of China. Copyright © 2007 SAGE Publications
Microscopic structure and dynamics of glass forming Zr2Co melts and the impact of different late transition metals on the melt properties
We studied the short-range order and the atomic dynamics of stable and undercooled binary Zr2Co alloy melts as
well as their density and viscosity. The containerless processing technique of electrostatic levitation was used to
achieve deep undercooling and to avoid contaminations. Static structure factors are determined by combining
this technique with neutron and high energy X-ray diffraction. Co self-diffusion coefficients are measured by
quasielastic neutron scattering. Our results reveal that the short-range order of the Zr2Co melts closely resembles
that previously observed for Zr64Ni36. We consider this as the origin of the very similar melt dynamics of these
two alloys at same temperatures. On the other hand, the difference in the structure and dynamics when
compared with those of Zr2Cu and Zr2Pd shows clearly that not only the atomic sizes, but also electronic
properties or chemical bonding have an important influence on the melt properties of Zr-based glass forming
melts
Measurement of K^+K^- production in two-photon collisions in the resonant-mass region
K^+K^- production in two-photon collisions has been studied using a large
data sample of 67 fb^{-1} accumulated with the Belle detector at the KEKB
asymmetric e^+e^- collider. We have measured the cross section for the process
gamma gamma -> K^+ K^- for center-of-mass energies between 1.4 and 2.4 GeV, and
found three new resonant structures in the energy region between 1.6 and 2.4
GeV. The angular differential cross sections have also been measured.Comment: 24 pages, 8 figures, to appear in Euro. Phys. Jour.
Study of charmonia in four-meson final states produced in two-photon collisions
We report measurements of charmonia produced in two-photon collisions and
decaying to four-meson final states, where the meson is either a charged pion
or a charged kaon. The analysis is based on a 395fb^{-1} data sample
accumulated with the Belle detector at the KEKB electron-positron collider. We
observe signals for the three C-even charmonia eta_c(1S), chi_{c0}(1P) and
chi_{c2}(1P) in the pi^+pi^-pi^+pi^-, K^+K^-pi^+pi^- and K^+K^-K^+K^- decay
modes. No clear signals for eta_c(2S) production are found in these decay
modes. We have also studied resonant structures in charmonium decays to
two-body intermediate meson resonances. We report the products of the
two-photon decay width and the branching fractions, Gamma_{gamma gamma}B, for
each of the charmonium decay modes.Comment: 22 pages, 12 figure
Search for new charmonium states in the processes e+ e- --> J/psi D(*) D(*) at sqrt{s} ~ 10.6 GeV
We present a study of the X(3940) state in the process e+e- -> J/psi D* Dbar.
The X(3940) mass and width are measured to be (3942 +7 -6 +- 6)MeV/c^2 and
Gamma=(37 + 26 - 15 +- 8 MeV. In the process e+e- -> J/psi D* D*bar we have
observed another charmonium-like state, which we denote as X(4160), in the
spectrum of invariant masses of D*+ D*- combinations. The X(4160) parameters
are M= 4156 + 25 - 20 +- 15 MeV/c^2 and Gamma = 139 + 111 -61 +- 21 MeV. The
analysis is based on a data sample with an integrated luminosity of 693 /fb
recorded near the Upsilon(4S) resonance with the Belle detector at the KEKB e+
e- asymmetric-energy collider.Comment: 7 pages, 2 figures Contribution paper for conferences EPS2007 and
Lepton Photon 2007, Belle-Conference-070
Search for the Rare Decays J/Psi --> Ds- e+ nu_e, J/Psi --> D- e+ nu_e, and J/Psi --> D0bar e+ e-
We report on a search for the decays J/Psi --> Ds- e+ nu_e + c.c., J/Psi -->
D- e+ nu_e + c.c., and J/Psi --> D0bar e+ e- + c.c. in a sample of 5.8 * 10^7
J/Psi events collected with the BESII detector at the BEPC. No excess of signal
above background is observed, and 90% confidence level upper limits on the
branching fractions are set: B(J/Psi --> Ds- e+ nu_e + c.c.)<4.8*10^-5, B(J/Psi
--> D- e+ nu_e + c.c.) D0bar e+ e- + c.c.)<1.1*10^-5Comment: 10 pages, 4 figure
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