Ah, to Be a Writer!

The spectrum of low molecular weight compounds, in particular of ribonucleotides, within first cleavage stage embryos of the polar lobe-forming mollusc Nassarius reticulatus and the distribution of the compounds within the embryo at the trefoil stage of first cleavage are analysed by means of capillary isotachophoresis after 0.5 M PCA extraction. The compounds which are found in the whole trefoil embryo (T), the lobeless part (LL), and the polar lobe (PL) respectively, and the mean quantities (nmol. µl-1; n=6) are: UTP (11.5, 4.8, 5.6), ITP (8.5, 3.6, 5.0), GTP (10.3, 3.0, 9.0), ATP (29.8, 13.4, 18.8), UDP (11.8, 3.4, 8.7), CTP (8.0, 3.1, 4.5), GDP (5.3, 2.6, 3.4), ADP(16.5, 6.1, 11.6), CDP(4.0, 1.4, 2.6), GMP (4.7, 2.7,4.3), glucose-6-phosphate (G6P) (53.5, 38.8, 13.0). These compounds appear to be localized in the non-yolk cytoplasmic pool. As the volume ratio of PL/LL for total volume and for non-yolk cytoplasmic volume is about 0.74 and 0.60 respectively, the concentration of all nucleotides in PL as compared to LL is significantly higher (HO,

Comparison of methanol and perchloric acid extraction procedures for analysis of nucleotides by isotachophoresis

no abstrac

Comparison of methanol and perchloric acid extraction procedures for analysis of nucleotides by isotachophoresis

no abstrac

Symbiosis of bacteria with eggs of Dentalium at the vegetal pole

After deposition of egg cells of Dentalium dentale L., hair-like protrusions, which are Feulgen-positive, are clearly visible at the vegetal pole. On checking the American species Dentalium antillarum it appeared that similar protrusions are visible in this species

XES tools

Process mining has emerged as a new way to analyze business processes based on event logs. These events logs need to be extracted from operational systems and can subsequently be used to discover or check the conformance of processes. ProM is a widely used tool for process mining. In earlier versions of ProM, MXML was used as an input format. In future releases of ProM, a new logging format will be used: The eXtensible Event Stream (XES) format. This format has several advantages over MXML. The paper presents two tools that use this format - XESMa and ProM6 - and highlights the main innovations and the role of XES. XESMa enables domain experts to specify how the event log should be extracted from existing systems and converted to XES. ProM6 is a completely new process mining framework based on XES and enabling innovative process mining functionality

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Molecular Epidemiolog