7 research outputs found
The Self Model and the Conception of Biological Identity in Immunology
- Author
- A.A. Freitas
- A.I. Tauber
- A.I. Tauber
- A.I. Tauber
- A.M. Silverstein
- A.M. Silverstein
- C.A. Buscaglia
- D. Haig
- D. Pardoll
- D. Wiggins
- D. Wilson
- D.C. Douek
- D.W. Bianchi
- E. Seung
- E.D. Carosella
- Edgardo D. Carosella
- F. Claas
- F. Marincola
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- G. Boniolo
- G.W. Leibniz
- H. Atlan
- H.G. Wells
- H.H. Smits
- I.R. Cohen
- I.R. Cohen
- J. Klein
- J. Savill
- J.B. Murphy
- J.F.A.P. Miller
- J.W. Kappler
- K.C. Garcia
- L. Margulis
- L.S.K. Walker
- L.V. Hooper
- M.L. Albert
- N. Girones
- N. Lila
- N. Nanda
- N.K. Jerne
- P. Ehrlich
- P. Godfrey-Smith
- P. Matzinger
- P.G. Ashton-Rickardt
- R. Lewontin
- R. Medzhitov
- R. Medzhitov
- R. Owen
- R. Pedotti
- R.D. Berg
- R.E. Billingham
- R.E. Langman
- R.M. Zinkernagel
- S. Oyama
- S. Sakaguchi
- S.F. Gilbert
- T. Pradeu
- T.A. Ferguson
- Thomas Pradeu
- V.R. Aluvihare
- W. Martin
- Y. Belkaid
- Y. Belkaid
- Publication venue
- Publication date
- 01/01/2005
- Field of study
The self/non-self model, first proposed by F.M. Burnet, has dominated immunology for sixty years now. According to this model, any foreign element will trigger an immune reaction in an organism, whereas endogenous elements will not, in normal circumstances, induce an immune reaction. In this paper we show that the self/non-self model is no longer an appropriate explanation of experimental data in immunology, and that this inadequacy may be rooted in an excessively strong metaphysical conception of biological identity. We suggest that another hypothesis, one based on the notion of continuity, gives a better account of immune phenomena. Finally, we underscore the mapping between this metaphysical deflation from self to continuity in immunology and the philosophical debate between substantialism and empiricism about identity
The Self Model and the Conception of Biological Identity in Immunology
- Author
- A.A. Freitas
- A.I. Tauber
- A.I. Tauber
- A.I. Tauber
- A.M. Silverstein
- A.M. Silverstein
- C.A. Buscaglia
- D. Haig
- D. Pardoll
- D. Wiggins
- D. Wilson
- D.C. Douek
- D.W. Bianchi
- E. Seung
- E.D. Carosella
- Edgardo D. Carosella
- F. Claas
- F. Marincola
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- F.M. Burnet
- G. Boniolo
- G.W. Leibniz
- H. Atlan
- H.G. Wells
- H.H. Smits
- I.R. Cohen
- I.R. Cohen
- J. Klein
- J. Savill
- J.B. Murphy
- J.F.A.P. Miller
- J.W. Kappler
- K.C. Garcia
- L. Margulis
- L.S.K. Walker
- L.V. Hooper
- M.L. Albert
- N. Girones
- N. Lila
- N. Nanda
- N.K. Jerne
- P. Ehrlich
- P. Godfrey-Smith
- P. Matzinger
- P.G. Ashton-Rickardt
- R. Lewontin
- R. Medzhitov
- R. Medzhitov
- R. Owen
- R. Pedotti
- R.D. Berg
- R.E. Billingham
- R.E. Langman
- R.M. Zinkernagel
- S. Oyama
- S. Sakaguchi
- S.F. Gilbert
- T. Pradeu
- T.A. Ferguson
- Thomas Pradeu
- V.R. Aluvihare
- W. Martin
- Y. Belkaid
- Y. Belkaid
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Are Inventories a Buffer Against Weak Legal Systems?.
- Author
- Aoki M.
- Bayly C.A.
- Beale H.
- Bental B.
- Blinder A.
- Buscaglia E.
- Buscaglia E.
- Clague C.
- Clague C.
- Cooter R.
- De Soto H.
- Dixit A.K.
- Dudley L.
- Easterly W.
- Ellickson R.C.
- Fafchamps F.
- Greif A.
- Greif A.
- Greif A.
- Greif A.
- Heritage Foundation
- Hollis A.
- Jiang Q.-Y.
- Macaulay S.
- North D.C.
- Redding S.G.
- Rodrik D.
- Schreiner M.
- Stiglitz J.E.
- Williamson O.E.
- Williamson O.E.
- World Bank
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Efficient anisotropic adaptive discretization of the cardiovascular system
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Enzootic transmission of Trypanosoma cruzi and T. rangeli in the Federal District of Brazil
- Author
- Alexandre Ramlo Torre Palma
- BARRETT T.V.
- BARRETTO M. P.
- BOSSENO M.F.
- BRENIÉRE S.F.
- BUSCAGLIA C.A.
- CARCAVALLO R.U.
- CUBA CUBA C.A.
- César Augusto Cuba Cuba
- D'ALESSANDRO A.
- DEANE L.M.
- DEVERA R.
- DIAS J.C.P.
- DIOTAIUTI L.
- DIOTAIUTI L.A.
- Eduardo Dias Ramalho
- FERNANDES A.J.
- FERNANDES O.
- Fernando Abad-Franch
- FORATTINI O.P.
- GAUNT M.
- GAUNT M.W.
- GRISARD E.C.
- GUHL F.
- GUHL F.
- GURGEL-GONÇALVES R.
- GURGEL-GONÇALVES R.
- JANSEN A.M.
- Julio Cesar Carranza
- MACEDO A.M.
- Marco Antônio Duarte
- MELLO D.A.
- MILES M.A.
- MILES M.A.
- MILES M.A.
- MILES M.A.
- MILES M.A.
- PALMA A.R.T.
- PINHO A.P.
- RABINOVICH J.
- RAMIREZ L.E.
- RAMIREZ L.E.
- RIBEIRO J.F.
- Rodrigo Gurgel-Gonçalves
- SANTOS A.H.
- SCHWEIGMANN N.J.
- SCHWEIGMANN N.J.
- SILVEIRA A.C.
- STEINDEL M.
- TIBAYRENC M.
- VALLEJO G.A.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
In Silico Chemogenomics Drug Repositioning Strategies for Neglected Tropical Diseases
- Author
- Achenbach J.
- Agüero F.
- Alirol E.
- Altschul S.F.
- Alves V.M.
- Alves V.M.
- Andersen S.L.
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- Aubé J.
- Awadzi K.
- Bahl A.
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- Neves B.J.
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- Nightingale S.L.
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- Van de Erve J.
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- Zumaquero-RÃos J.L.
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- Publication venue
- 'Bentham Science Publishers Ltd.'
- Publication date
- Field of study
Error estimates and adaptive finite element methods
- Author
- Aalto J.
- Aalto J.
- Aalto J.
- Acosta G.
- Adamiak K.
- Ainsworth M.
- Ainsworth M.
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- Babuska I.M.
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- Baehmann P.L.
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- Baldi A.
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- Publication venue
- 'Emerald'
- Publication date
- Field of study