Migration and Final Location of Hot Super Earths in the Presence of Gas Giants

Based on the conventional sequential-accretion paradigm, we have proposed that, during the migration of first-born gas giants outside the orbits of planetary embryos, super Earth planets will form inside the 2:1 resonance location by sweeping of mean motion resonances (Zhou et al. 2005). In this paper, we study the subsequent evolution of a super Earth (m_1) under the effects of tidal dissipation and perturbation from a first-born gas giant (m_2) in an outside orbit. Secular perturbation and mean motion resonances (especially 2:1 and 5:2 resonances) between m_1 and m_2 excite the eccentricity of m_1, which causes the migration of m_1 and results in a hot super Earth. The calculated final location of the hot super Earth is independent of the tidal energy dissipation factor Q'. The study of migration history of a Hot Super Earth is useful to reveal its Q' value and to predict its final location in the presence of one or more hot gas giants. When this investigation is applied to the GJ876 system, it correctly reproduces the observed location of GJ876d around 0.02AU.Comment: 7 pages, 4 figure

Differentiation of pluripotent stem cells into endothelial cells

PURPOSE OF REVIEW: Methods to isolate endothelial cells from murine and human pluripotent stem cells continue to evolve and increasingly diverse endothelial cell populations have been generated. This review provides an update of key articles published within the past year that report on some of those advances. RECENT FINDINGS: Cooperative interactions among microRNA (miRNA), transcription factors and some downstream interacting proteins have been reported to enhance endothelial specification from embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Endothelial cell differentiation can also be modulated by various growth factor additions, Notch pathway activation or inhibition, and modulation of the microenvironment of the differentiating ESC and iPSC. Functionality of the derived endothelium has been demonstrated by a variety of in-vitro and in-vivo assays. Finally, two recent reports have identified endothelial progenitor populations with robust proliferative potential. SUMMARY: Progress in differentiating endothelial cells from ESC and iPSC has been made. The recent report of formation of endothelial colony forming cells from human ESC and iPSC provides a protocol that can generate clinically relevant numbers of cells for human cell therapy

Low-energy photoelectron transmission through aerosol overlayers

The transmission of low-energy (<1.8eV) photoelectrons through the shell of core-shell aerosol particles is studied for liquid squalane, squalene, and DEHS shells. The photoelectrons are exclusively formed in the core of the particles by two-photon ionization. The total photoelectron yield recorded as a function of shell thickness (1-80nm) shows a bi-exponential attenuation. For all substances, the damping parameter for shell thicknesses below 15nm lies between 8 and 9nm, and is tentatively assigned to the electron attenuation length at electron kinetic energies of ~0.5-1eV. The significantly larger damping parameters for thick shells (> 20nm) are presumably a consequence of distorted core-shell structures. A first comparison of aerosol and traditional thin film overlayer methods is provided

Endothelial stem and progenitor cells (stem cells): (2017 Grover Conference Series)

The capacity of existing blood vessels to give rise to new blood vessels via endothelial cell sprouting is called angiogenesis and is a well-studied biologic process. In contrast, little is known about the mechanisms for endothelial cell replacement or regeneration within established blood vessels. Since clear definitions exist for identifying cells with stem and progenitor cell properties in many tissues and organs of the body, several groups have begun to accumulate evidence that endothelial stem and progenitor cells exist within the endothelial intima of existing blood vessels. This paper will review stem and progenitor cell definitions and highlight several recent papers purporting to have identified resident vascular endothelial stem and progenitor cells

Mutants with increased sensitivity to caffeine

Mutants with increased sensitivity to caffein

Guanine-requiring mutants

Guanine-requiring mutant